A child or individual has a personal or family history of:

• One or more birth defects such as congenital heart defects, spina bifida, and cleft lip.
• Altered growth patterns.
• Developmental delay, mental retardation or certain neurological disorders.
• A known or suspected genetic or chromosomal disorder, such as cystic fibrosis, muscular dystrophy or Down syndrome neurofibromatosis or Marfan syndrome.
• Major behavioral/psychiatric problem.
• Seizure disorder.
• Certain types of cancer, such as early onset breast or colon cancer, ovarian cancer at any age. 

A couple with:

• Multiple pregnancy losses.
• Ethnic backgrounds associated with an increased risk for genetic disease.
• Consanguinity.
• Advanced parental age.
• Abnormal prenatal test results, including ultrasound, serum marker screening and/or prenatal diagnosis results.
• Infertility, including egg donor screening.

Cancer genetic counseling is also available through the Moffitt Cancer Center Lifetime Cancer Screening Center.