The Florida Perinatal Quality Collaborative was established in 2010 to improve Florida’s maternal and infant health outcomes through the delivery of high quality, evidence-based perinatal care.In order to achieve this goal, the FPQC consists of statewide partnerships with perinatal-related organizations, individuals, health professionals, advocates, policymakers, hospitals and payers (FPQC stakeholders). These stakeholders have been working voluntarily in data-driven, population-based, quality improvement (QI) processes focused on some of the most critical perinatal health issues in Florida. Led by a Steering Committee and a leadership team, the FPQC engages all of its stakeholders to identify the priority perinatal QI issues and to determine which initiatives are appropriate, feasible, engaging, measurable and supportable. The FPQC seeks to create an all-inclusive culture of cooperation and transparency across the specialties of obstetrics, neonatology, pediatrics and all fields engaged in maternal and infant health care by bringing together the specific expertise of physicians, nurses, nurse-midwives and all specialists involved with perinatal-related health care. By promoting this teamwork, information sharing and variety across disciplines and professions, the FPQC continues to move forward towards achieving its vision of delivering the highest quality of health care outcomes for Florida’s mothers and infants.