College is a time for growth, exploration and independence. It is also a time where young adults may face challenges to their health and well-being due to experiencing behavioral-associated threats to health that are unique to college life. For most students, not only do "college-appropriate" behavior patterns (e.g., unhealthy eating, poor sleep, sedentary behaviors) typically become predictors of overall health in adulthood, they frequently lead to less healthy and often stressful behaviors, such as smoking and drinking. The Center for Transdisciplinary Research in College Health and Well-being seeks to create new paradigms for college health, well-being and success through innovative transdisciplinary research and practice.