Dr. Wang's laboratory focuses on the molecular mechanisms of cardiac, smooth and skeletal muscle development and diseases. They revealed that myocardin is essential for cardiovascular development. Over the past decade, the Wang lab studies non-coding RNAs, in particular microRNAs (miRNAs) and they have demonstrated that miRNAs play a critical role in controlling cardiac and skeletal muscle proliferation and differentiation. Their lab also studies the function and molecular mechanisms of long non-coding RNAs (lncRNAs) in the heart and cardiovascular disease. Dr. Wang has made substantial contribution to our understanding of the molecular mechanisms underlying heart development and disease.
Dr. Wang's discovery of myocardin represents a landmark which has opened an entire new area in the cardiovascular biology and has now become the focus of intense investigation by many laboratories around the world.
