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Cao Lab

Research

Our Focus

Major research focus is to study the role of immune system in disease development and find a cure to treat diseases through immune modulation approach including vaccination and natural product. I am currently working on vaccine for Alzheimer's disease and Parkinson's disease.

Selected Publications

Song G, Yang H, Pham P, Brown B, Lin X, Hong Y, Sinu P, Cai J, Li X, Leon M, Gordon M, Morgan D, Zhang S, and Cao C. An Immunomodulatory Therapeutic Vaccine Targeting Oligomeric Amyloid Beta. J Alzheimers Dis. 2020. PMID: 32925044.

Shen N, Song G, Yang H, Lin X, Brown B, Hong Y, Cai J, Cao C. Identifying the Pathological Domain of Alpha- Synuclein as a Therapeutic for Parkinson’s Disease Int J Mol Sci. 2019 May 11;20(9). pii: E2338.

Chen Y, Yang JL, Xue ZZ, Cai QC, Hou C, Li HJ, Zhao LX, Zhang Y, Gao CW, Cong L, Wang TZ, Chen DM, Luo SQ, Yao Q, Zhu QS, Cao C Effects and mechanism of microRNA-218 against lung cancer Molecular Medicine Reports 2020 https://doi.org/10.3892/mmr.2020.11666

Wang M, Gao R, Sang P, Zheng M, Shi Y, Xu H, Cao C, and Cai J,. Dimeric γ-AApeptides with Potent and Selective Antibacterial Activity Front. Chem. 2020|

Su, M., Wang, M., Hong, Y., Nimmagadda, A., Shen, N., Shi, Y., Gao, R., Zhang, E. Cao, C., Cai, J. 2019. Polymyxin derivatives as broad-spectrum antibiotic agents. Chemical Communications, 55(87), 13104-13107.

Perez A, Li T, Hernandez S, Zhang RY, and Cao C. The Rationale of using Coffee and Melatonin as Alternative Treatment for Alzheimer’s disease. J of Alz Dis and Parkinsonism. Jan 2016, 6:205

Lin X, Bai G, Sutherland K, Costanza F, Breitenkamp K, Sill K, Cai J, Cao C. Polymer-Encapsulated Aβ Peptide Fragments as an Oligomeric-Specific Vaccine for Alzheimer’s disease. J. Biomed. Nanotechnol., 2016 Jul 12(7), 1421-1430.

Cao, C., Li, Y., Liu, H., Bai, G., Mayl, J., Lin, X., Sutherland, K., Nabar, N., Cai, J., 2014. The potential therapeutic effects of THC on Alzheimer’s disease. J. Alzheimers Dis. JAD 42, 973–984.

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