PhD, Biochemistry, University of Mississippi, 2012
Interdisciplinary and Emerging Signature Programs
Allergy, Immunology & Infectious Disease
Biomedical Engineering & Nanomedicine
Cardiovascular
Cellular and Molecular Biology
Metabolic Regulation and Disorders
Research Interests
My research is focused on the regulation of blood pressure and renal function. The aim of my research is to better understand the mechanisms in control of renal hemodynamics and salt-water balance under physiological and pathophysiological conditions and the renal mechanisms for kidney injury and graft dysfunction after kidney transplantations. The goal of my studies is to identify potential therapeutic targets contributing to the improvement of renal function. Methods applied to my studies include: microperfusion of kidney tubules and arterioles in vitro, whole-animal physiology, acute and chronic measurements of arterial pressure, renal function reservation assessment in anesthetized and awake mice, implantation of transmitters in rats and mice for telemetry blood pressure measurement, organ (kidney,liver and lung) transplantation in rodents.
Recent Publications
Wang L, Wei J, Jiang S, Li HH, Fu L, Zhang J, Liu R. Effects of different storage solutions on renal ischemia tolerance after kidney transplantation in mice.American journal of physiology. Renal physiology. 314(3) : F381-F387, 2018.
Wang L, Wang X, Jiang S, Wei J, Buggs J, Fu L, Zhang J, Liu R. Graft function assessment in mouse models of single- and dual-kidney transplantation.American journal of physiology. Renal physiology. 315(3) : F628-F636, 2018.
Song J, Wang L, Fan F, Wei J, Zhang J, Lu Y, Fu Y, Wang S, Juncos LA, Liu R. Role of the Primary Cilia on the Macula Densa and Thick Ascending Limbs in Regulation of Sodium Excretion and Hemodynamics.Hypertension (Dallas, Tex. : 1979). 70(2) : 324-333, 2017.
Wang L, Wang X, Qu HY, Jiang S, Zhang J, Fu L, Buggs J, Pang B, Wei J, Liu R. Role of Kidneys in Sex Differences in Angiotensin II-Induced Hypertension.Hypertension (Dallas, Tex. : 1979). 70(6) : 1219-1227, 2017.
Wei J, Song J, Jiang S, Zhang G, Wheeler D, Zhang J, Wang S, Lai EY, Wang L, Buggs J, Liu R. Role of intratubular pressure during the ischemic phase in acute kidney injury.American journal of physiology. Renal physiology. 312(6) : F1158-F1165, 2017.
Wang L, Song J, Buggs J, Wei J, Wang S, Zhang J, Zhang G, Lu Y, Yip KP, Liu R. A new mouse model of hemorrhagic shock-induced acute kidney injury.American journal of physiology. Renal physiology. 312(1) : F134-F142, 2017.
Wang L, Song J, Wang S, Buggs J, Chen R, Zhang J, Wang L, Rong S, Li W, Wei J, Liu R. Cross-sex transplantation alters gene expression and enhances inflammatory response in the transplanted kidneys.American journal of physiology. Renal physiology. 313(2) : F326-F338, 2017.
Wang X, Chandrashekar K, Wang L, Lai EY, Wei J, Zhang G, Wang S, Zhang J, Juncos LA, Liu R. Inhibition of Nitric Oxide Synthase 1 Induces Salt-Sensitive Hypertension in Nitric Oxide Synthase 1α Knockout and Wild-Type Mice.Hypertension (Dallas, Tex. : 1979). 67(4) : 792-9, 2016.
Wang L, Shen C, Liu H, Wang S, Chen X, Roman RJ, Juncos LA, Lu Y, Wei J, Zhang J, Yip KP, Liu R. Shear stress blunts tubuloglomerular feedback partially mediated by primary cilia and nitric oxide at the macula densa.American journal of physiology. Regulatory, integrative and comparative physiology. 309(7) : R757-66, 2015.
Lu Y, Zhang R, Ge Y, Carlstrom M, Wang S, Fu Y, Cheng L, Wei J, Roman RJ, Wang L, Gao X, Liu R. Identification and function of adenosine A3 receptor in afferent arterioles.American journal of physiology. Renal physiology. 308(9) : F1020-5, 2015.
