Molecular Pharmacology and Physiology


Recent Publications

Fibroblasts repair blood-brainbarrier damage and hemorrhagic brain injury via TIMP2

Xu L, Nirwane A, Xu T, Kang M, Devasani K, Yao Y. Cell Rep. 2022 Nov 22

Modulation of P2X4 receptor activity by ivermectin and 5-BDBD has no effect on the development of ARPKD in PCK rats

Xu B, Nikolaienko O, Levchenko V, Choubey AS, Isaeva E, Staruschenko A, Palygin O. Physiol Rep. 2022 Nov 10

ElevatedLDL-cholesterol levels among lean mass hyper-responders on low-carbohydrateketogenic diets deserve urgent clinical attention and further research

Norwitz NG, Mindrum MR, Giral P, Kontush A, Soto-Mota A, Wood TR, D'Agostino DP, Manubolu VS, Budoff M, Krauss RM. J Clin Lipidol. 2022 Nov 2

TheMicrovascular-Lymphatic Interface and Tissue Homeostasis: Critical QuestionsThat Challenge Current Understanding

Lampejo AO, Jo M, Murfee WL, Breslin JW. J Vasc Res. 2022 Oct 31

IKACh isconstitutively active via PKC epsilon in aging mediated atrial fibrillation

Chang M, Gada KD, Chidipi B, Tsalatsanis A, Gibbons J, Remily-Wood E, Logothetis DE, Oberstaller J, Noujaim SF. iScience. 2022 Oct 25

Anti-atherosclerotic therapies: Milestones, challenges, and emerging innovations

Hetherington I, Totary-Jain H. Mol Ther. 2022 Oct 5

TacrolimusCauses Hypertension by Increasing Vascular Contractility via RhoA (Ras HomologFamily Member A)/ROCK (Rho-Associated Protein Kinase) Pathway in Mice

Wang X, Jiang S, Fei L, Dong F, Xie L, Qiu X, Lei Y, Guo J, Zhong M, Ren X, Yang Y, Zhao L, Zhang G, Wang H, Tang C, Yu L, Liu R, Patzak A, Persson PB, Hultström M, Wei Q, Lai EY, Zheng Z. Hypertension. 2022 Oct

Impact of Goreisan componentson rat mesenteric collecting lymphatic vessel pumping

Jo M, Trujillo AN, Shibahara N, Breslin JW. Microcirculation. 2022 Sep 28

The Arf6/PIP5K pathway activates IKACh in cigarette smoke mediated atrialfibrillation

Chidipi B, Chang M, Abou-Assali O, Reiser M, Tian Z, Allen-Gipson D, Noujaim SF. Cell Signal. 2022 Sep 20

Concentrationand proteolysis of CX3CL1 may regulate the microglial response to CX3CL1

Finneran D, Li Q, Subbarayan MS, Joly-Amado A, Kamath S, Dengler DG, Gordon MN, Jackson MR, Morgan D, Bickford PC, Smith LH, Nash KR. Glia. 2022 Sep 15

Knockoutof the Circadian Clock Protein PER1 (Period1) Exacerbates Hypertension andIncreases Kidney Injury in Dahl Salt-Sensitive Rats

Zietara A, Spires DR, Juffre A, Costello HM, Crislip GR, Douma LG, Levchenko V, Dissanayake LV, Klemens CA, Nikolaienko O, Geurts AM, Gumz ML, Staruschenko A. Hypertension. 2022 Sep 12

Sodiumphosphate cotransporter 2a inhibitors: potential therapeutic uses

Xue J, Thomas L, Dominguez Rieg JA, Rieg T. Curr Opin Nephrol Hypertens. 2022 Sep 1



MPP News:

USF awarded five-year, $1.35 million NIH institutional grant to train scientists in vascular inflammation and injury research

Trainees will benefit from USF Health’s increase in nationally recognized faculty with research expertise in blood vessel inflammation linked to heart, lung, and other diseases TAMPA, Fla […]


Deletion of single gene promotes growth of functional lymphatic valves

Targeting the gene Foxo1 may offer an early treatment approach for hereditary lymphedema, USF Health preclinical study reports Tampa, FL (Aug. 9, 2021) — A University of South […]

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Cell-selective nanotherapy prevents vessel renarrowing and promotes healing of arteries opened by angioplasty

A USF Health preclinical study indicates nanoparticles containing a micro-RNA switch offers promising biotechnology to advance the fight against atherosclerotic cardiovascular disease Tampa, FL (Feb. 9, 2021) – […]

Angioplasty with a stent