" This Laboratory is studying a group of Cardiac Hormones called natriuretic peptides because they are hormones secreted by the heart that increase the excretion of sodium (Na) by the kidneys (uretic).
" These hormones are part of a naturally occurring mechanism that is important in regulating blood volume and blood pressure.
Salt Intake ® Blood Volume Expansion and Stretch of the Atria ® atrial natriuretic peptide (ANP) Secretion.
ANP increases salt and water excretion to reduce blood volume and blood pressure.
ANP also directly dilates blood vessels which helps to lower blood pressure.
Work in this area over the past 20 years has already resulted in new drugs to treat hypertension and heart failure.
Awards/Honors
USF Presidents Award for Faculty Excellence (University of South Florida - 2003)
Outstanding Contrib. to USF Coll. of Med. Teaching Award (University of South Florida - 2000)
USF Teaching Incentive Program (TIP) Award (University of South Florida - 1998)
Distinguished Teacher Award - USF Medical Class of 1996 (University of South Florida - 1996)
Memberships
Member (American Physiological Society, 1979 - Present)
Recent Publications
Dietz JR. Mechanisms of atrial natriuretic peptide secretion from the atrium.Cardiovascular research. 68(1) : 8-17, 2005.
Dietz JR. Using Willie''s acid-base box for blood gas analysis.Advances in physiology education. 35(4) : 454-5, 2011.
Dietz JR, Stevenson FT. Active learning in a large medical classroom setting for teaching renal physiology.Advances in physiology education. 35(4) : 456-9, 2011.
Addisu A, Gower WR, Serrano M, Villarreal D, Dietz JR. Heart failure mice exhibit decreased gastric emptying and intestinal absorption.Experimental biology and medicine (Maywood, N.J.). 236(12) : 1454-60, 2011.
Kshatriya, K, Reams, GP, Spear, RM, Freeman, RH, DIETZ, JR, Villarreal, D. Obesity-Hypertension: The Emerging Role of Leptin in Renal and Cardiovascular DyshomeostasisCurrent Opinion in Nephrology and Hypertension. 19(1) : 72-78, 2010.
Jacob VA, Harbaugh CM, Dietz JR, Fenton RA, Kim SM, Castrop H, Schnermann J, Knepper MA, Chou CL, Anderson SA. Magnetic resonance imaging of urea transporter knockout mice shows renal pelvic abnormalities.Kidney international. 74(9) : 1202-8, 2008.
Addisu A, Gower WR, Landon CS, DIETZ JR. B-Type Natriuretic Peptide Decreases Gastric Emptying and AbsorptionExp Biol Med. 233(4) : 475-482, 2008.
Wall SM, Knepper MA, Hassell KA, Fischer MP, Shodeinde A, Shin W, Pham TD, Meyer JW, Lorenz JN, Beierwaltes WH, Dietz JR, Shull GE, Kim YH. Hypotension in NKCC1 null mice: role of the kidneys.American journal of physiology. Renal physiology. 290(2) : F409-16, 2006.
Positions Held
Professor (Molecular Pharmacology & Physiology, USF, College of Medicine 2006 - 2007)
Professor (Physiology & Biophysics, USF, College of Medicine 1993 - 2006)
Assistant Professor (Physiology & Biophysics, USF, College of Medicine 1982 - 1997)
Associate Professor (Physiology & Biophysics, USF, College of Medicine 1988 - 1993)
Research Associate (Physiology, Medicine, Univ Missouri 1979 - 1982)
