Molecular Pharmacology & Physiology

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Research in the Molecular Pharmacology & Physiology concentration in the PhD Program in Integrated Biomedical Sciences is focused on interdisciplinary approaches to the study of nervous and cardiovascular systems and related disorders, including Alzheimer’s disease, neurodegenerative disorders, cardiovascular disease, stroke, diabetes, and neuropsychiatric disorders such as depression and drug addiction. Training will include a unique interdisciplinary blend of didactic coursework, journal clubs, seminar series, as well as significant research experience. The goal of the research programs in the Department of Molecular Pharmacology & Physiology is to translate studies that decipher mechanisms of diseases or discover novel diagnostic/therapeutic targets into improved healthcare.   

Courses

In addition to the coursework required for all students in the PhD Program in Integrated Biomedical Sciences, students will take courses in their chosen concentration. 

Required

  • GMS 6440 Basic Medical Physiology
  • GMS 6505 Basic Medical Pharmacology
  • GMS 7930 Advanced Medical Physiology or Advanced Medical Pharmacology 

Sample of Electives 

  • GMS 6707 Neuroscience 
  • GMS 7930 Advanced Neuroscience
  • GMS 6401 Kidney, Fluids and Electrolytes
  • GMS 6403 Endocrine Mechanisms 
  • GMS 6404 Systems Neurophysiology 

Faculty & Research

Current research interests include: 

  • Renal Pathophysiology and Hypertension
  • Microcirculation, Lymphatic Biology, Cell and Matrix Molecular Biology
  • Glycobiology
  • Hyperbaric Neurophysiology 
  • Cellular and Molecular Mechanisms of CNS Oxygen Toxicity
  • Neural Plasticity with neurodegenerative disease and after brain injury

Learn more about our faculty and their research here

Affiliated Institutes & Facilities

Neuroscience Institute


Concentration Spotlights

News

Jay Lockhart presents at research day

Fifth year PhD student, Jay Lockhart was selected to give an oral presentation at USF Health Research Day. 







Recent Publications 

    • Lockhart J Canfield J Mong EF VanWye J Totary-Jain. Nucleotide Modification Alters MicroRNA-Dependent Silencing of MicroRNA Switches Mol Ther Nucleic Acids. 12(7) : 339-350, 2018. https://doi.org/10.1016/j.omtn.2018.12.007
    • Canfield J Arlier S Mong EF Lockhart J VanWye J Guzelogu-Kayisli O Schatz F Magness RR Lockwood CJ Tsibris JCM Kayisli USF Totary-Jain H. Decreased LIN28B in preeclampsia impairs human trophoblast differentiation and migration FASEB J., 2018. https://doi.org/10.1096/fj.201801163R 
    • Modulation of LIN28B/Let-7 Signaling by Propranolol Contributes to Infantile Hemangioma Involution Ezinne Francess Mong, Kemal Marc Akat, John Canfield, John Lockhart, Jeffrey VanWye, Andrew Matar, John C.M. Tsibris, June K. Wu, Thomas Tuschl, Hana Totary-Jain
      Arteriosclerosis, Thrombosis, and Vascular Biology. 2018;38:1321-1332 Originally published May 3, 2018. https://doi.org/10.1161/ATVBAHA.118.310908 
    • Glucose dilates renal afferent arterioles via glucose transporter-1 Jie Zhang, Shan Jiang, Jin Wei, Kay-Pong Yip, Lei Wang, En Yin Lai, and Ruisheng Liu. 01 JUL 2018. https://doi.org/10.1152/ajprenal.00409.2017
    • Wang L, Song J, Buggs J, Wei J, Wang S, Zhang J, Zhang G, Lu Y, Yip KP, Liu R. A new mouse model of hemorrhagic shock-induced acute kidney injury. American journal of physiology. Renal physiology. 312(1) : F134-F142, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28042109

More Information

For information about the PhD Program in Integrated Biomedical Sciences, contact 813-974-2836 or biomedphd@health.usf.edu. 

Apply Now 

Please note, students do not apply directly to a concentration. Interested students should submit an application for the PhD in Medical Sciences. Concentrations are typically selected during the first year of study.