Molecular Pharmacology & Physiology

Research in the Molecular Pharmacology & Physiology concentration in the PhD Program in Integrated Biomedical Sciences is focused on interdisciplinary approaches to the study of nervous and cardiovascular systems and related disorders, including Alzheimer’s disease, neurodegenerative disorders, cardiovascular disease, stroke, diabetes, and neuropsychiatric disorders such as depression and drug addiction. Training will include a unique interdisciplinary blend of didactic coursework, journal clubs, seminar series, as well as significant research experience. The goal of the research programs in the Department of Molecular Pharmacology & Physiology is to translate studies that decipher mechanisms of diseases or discover novel diagnostic/therapeutic targets into improved healthcare.   

Concentration Spotlights

News

Fifth year PhD student, Jay Lockhart was selected to give an oral presentation at USF Health Research Day. 

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Recent Publications 

• Lockhart J Canfield J Mong EF VanWye J Totary-Jain. Nucleotide Modification Alters MicroRNA-Dependent Silencing of MicroRNA Switches Mol Ther Nucleic Acids. 12(7) : 339-350, 2018. https://doi.org/10.1016/j.omtn.2018.12.007
• Canfield J Arlier S Mong EF Lockhart J VanWye J Guzelogu-Kayisli O Schatz F Magness RR Lockwood CJ Tsibris JCM Kayisli USF Totary-Jain H. Decreased LIN28B in preeclampsia impairs human trophoblast differentiation and migration FASEB J., 2018. https://doi.org/10.1096/fj.201801163R 
• Modulation of LIN28B/Let-7 Signaling by Propranolol Contributes to Infantile Hemangioma Involution Ezinne Francess Mong, Kemal Marc Akat, John Canfield, John Lockhart, Jeffrey VanWye, Andrew Matar, John C.M. Tsibris, June K. Wu, Thomas Tuschl, Hana Totary-Jain
  Arteriosclerosis, Thrombosis, and Vascular Biology. 2018;38:1321-1332 Originally published May 3, 2018. https://doi.org/10.1161/ATVBAHA.118.310908 
• Glucose dilates renal afferent arterioles via glucose transporter-1 Jie Zhang, Shan Jiang, Jin Wei, Kay-Pong Yip, Lei Wang, En Yin Lai, and Ruisheng Liu. 01 JUL 2018. https://doi.org/10.1152/ajprenal.00409.2017
• Wang L, Song J, Buggs J, Wei J, Wang S, Zhang J, Zhang G, Lu Y, Yip KP, Liu R. A new mouse model of hemorrhagic shock-induced acute kidney injury. American journal of physiology. Renal physiology. 312(1) : F134-F142, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28042109