Byrd Alzheimer’s Institute publications for the past five (5) years.

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Mok SA, Condello C, Freilich R, Gillies A, Arhar T, Oroz J, etc al. Mapping interactions with the chaperone network reveals factors that protect against tau aggregation. Nat Struct Mol Biol 25(5): 384-393. 2018. https://www.ncbi.nlm.nih.gov/pubmed/29728653

Gulick D, Gamsby JJ. Racing the clock: The role of circadian rhrythmicity in addiction across the lifespan. Pharmacol Ther. 2018. https://www.ncbi.nlm.nih.gov/pubmed/29551440

Criado-Marrero M, Rein T, Binder EB, Porter JT, Koren J, Blair LJ. Hsp90 and FKBP51: complex regulators of psychiatric diseases. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 373(1738). 2018. http://www.ncbi.nlm.nih.gov/pubmed/29203717

Klinger RY, James OG, Borges-Neto S, Bisanar T, Li YJ, Qi W, Berger M, et al. 18-F-florbetapir positron emission tomography-determined cerebral beta-amyloid deposition and neurocognitive performance after cardiac surgery. Anesthesiology 128(4): 728-744. 2018. https://www.ncbi.nlm.nih.gov/pubmed/29389750

Kim D Cho S Woo JA Liggett SB. A CREB-mediated increase in miRNA let-7f during prolonged β-agonist exposure: a novel mechanism of β2-adrenergic receptor down-regulation in airway smooth muscle. FASEB J. 2018. https://www.ncbi.nlm.nih.gov/pubmed/29455573

El Hokayem J, Weeber E, Nawaz Z. Loss of Angelman syndrome protein E6AP disrupts a novel antagonistic estrogen-retinoic acid transcriptional crosstalk in neurons. Mol Neurobiol. 2018. https://www.ncbi.nlm.nih.gov/pubmed/29388081

Liggett SB. Genetic vulnerability of GPCRs: A call to action. Trends Biochem Sci 43(4):227-229. 2018. https://www.ncbi.nlm.nih.gov/pubmed/29605062

Huard DJE, Crowley VM, Du Y, Cordova RA, Sun Z, Tomlin MO, Dickey CA, Koren J 3rd, Blair L, Fu H, Blagg BSJ, Lieberman RL. Trifunctional high-throughput screen identifies promising scaffold to inhibit Grp94 and treat myocilin-associated glaucoma. ACS Chem Biol 13(4): 933-941. 2018. https://www.ncbi.nlm.nih.gov/pubmed/29402077

Panettieri RA, Pera T, Liggett SB, Benovic JL, Penn RB. Pepducins as a potential treatment strategy for asthma and COPD. Curr Opin Pharmacol 40: 120-125. 2018. https://www.ncbi.nlm.nih.gov/pubmed/29729548

Xu H Dorn II GW Shetty A Parihar A Dave T Robinson SW Gottlieb SS Donahue MP Tomaselli GF Kraus WE Mitchell BD Liggett SB. A genome-wide association study of idiopathic dilated cardiomyopathy in African Americans. J Pers Med.. 8(11) : doi:10.3390/jpm8010011, 2018. https://www.ncbi.nlm.nih.gov/pubmed/29495422

An SS Liggett SB. Taste and smell GPCRs in the lung: Evidence for a previously unrecognized widespread chemosensory system. Cell Signal.. 41: 82-88, 2018. https://www.ncbi.nlm.nih.gov/pubmed/28167233

Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer’s disease. Nature Genetics. 49(9): 1373-1384. 2017. https://www.ncbi.nlm.nih.gov/pubmed/28714976

Baker JD, Shelton LB, Zheng D, Favretto F, Nordhues BA, Darling A, Sullivan LE, Sun Z, Solanki PK, Martin MD, Suntharalingam A, Sabbagh JJ, Becker S, Mandelkow E, Uversky VN, Zweckstetter M, Dickey CA, Koren J, Blair LJ. Human cyclophilin 40 unravels neurotoxic amyloids. PLoS biology. 15(6) : e2001336, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28654636

Witas R, Chaput D, Khan H, Stevens SM, Kang D. Isolation and Proteomic Analysis of Microvesicles and Exosomes from HT22 Cells and Primary Neurons. Methods in molecular biology (Clifton, N.J.). 1598: 255-267, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28508366

Woo JA, Liu T, Trotter C, Fang CC, De Narvaez E, LePochat P, Maslar D, Bukhari A, Zhao X, Deonarine A, Westerheide SD, Kang DE. Loss of function CHCHD10 mutations in cytoplasmic TDP-43 accumulation and synaptic integrity. Nature communications. 8: 15558, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28585542

Russo MJ, Campos J, Vázquez S, Sevlever G, Allegri RF, et al. Adding recognition discriminability index to the delayed recall is useful to predict conversion from mild cognitive impairment to Alzheimer’s disease in the Alzheimer’s disease neuroimaging initiative. Front Aging Neurosci. 9: 46. 2017. https://www.ncbi.nlm.nih.gov/pubmed/28344552

Stothert AR, Suntharalingam A, Tang X, Crowley VM, Mishra SJ, Webster JM, Nordhues BA, Huard DJE, Passaglia CL, Lieberman RL, Blagg BSJ, Blair LJ, Koren J 3rd, Dickey CA. Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma. Sci Rep 7(1): 17951. 2017. https://www.ncbi.nlm.nih.gov/pubmed/29263415

Liu T, Wang F, LePochat P, Woo JA, Bukhari MZ, Hong KW, Trotter C, Kang DE. Cofilin-mediated Neuronal Apoptosis via p53 Translocation and PLD1 Regulation. Scientific reports. 7(1) : 11532, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28912445

Kim D, Woo JA, Geffken E, An SS, Liggett SB. Coupling of Airway Smooth Muscle TAS2Rs to Intracellular Signaling and Relaxation is via Gαi1,2,3. American journal of respiratory cell and molecular biology. , 2017. http://www.ncbi.nlm.nih.gov/pubmed/28145731

Woo JA, Liu T, Zhao X, Trotter C, Yrigoin K, Cazzaro S, Narvaez E, Khan H, Witas R, Bukhari A, Makati K, Wang X, Dickey C, Kang DE. Enhanced tau pathology via RanBP9 and Hsp90/Hsc70 chaperone complexes. Human molecular genetics. 26(20) : 3973-3988, 2017. http://www.ncbi.nlm.nih.gov/pubmed/29016855

Grimmig B, Kim SH, Nash K, Bickford PC, Douglas Shytle R. Neuroprotective mechanisms of astaxanthin: a potential therapeutic role in preserving cognitive function in age and neurodegeneration. GeroScience. 39(1) : 19-32, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28299644

Born HA, Dao AT, Levine AT, Lee WL, Mehta NM, Mehra S, Weeber EJ, Anderson AE. Strain-dependence of the Angelman Syndrome phenotypes in Ube3a maternal deficiency mice. Scientific reports. 7(1) : 8451, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28814801

Stevanovic K, Yunus A, Joly-Amado A, Gordon M, Morgan D, Gulick D, Gamsby J. Disruption of normal circadian clock function in a mouse model of tauopathy. Experimental neurology. 294: 58-67, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28461004

Smith-McLallen A, Heller D, Vernisi K, Gulick D, Cruz S, Snyder RL. Comparative Effectiveness of Two Walking Interventions on Participation, Step Counts, and Health. American journal of health promotion: AJHP. 31(2) : 119-127, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28423931

Shelton LB, Baker JD, Zheng D, Sullivan LE, Solanki PK, Webster JM, Sun Z, Sabbagh JJ, Nordhues BA, Koren J, Ghosh S, Blagg BSJ, Blair LJ, Dickey CA. Hsp90 activator Aha1 drives production of pathological tau aggregates. Proceedings of the National Academy of Sciences of the United States of America. 2017. http://www.ncbi.nlm.nih.gov/pubmed/28827321

Fontaine SN, Zheng D, Sabbagh JJ, Martin MD, Chaput D, Darling A, Trotter JH, Stothert AR, Nordhues BA, Lussier A, Baker J, Shelton L, Kahn M, Blair LJ, Stevens SM, Dickey CA. DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins. The EMBO journal. 35(14) : 1537-49, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27261198

Song S, Kong X, Sava V, Cao C, Acosta S, Borlongan C, Sanchez-Ramos J. Transient Micro-needle Insertion into Hippocampus Triggers Neurogenesis and Decreases Amyloid Burden in a Mouse Model of Alzheimer's Disease. Cell transplantation. , 2016. http://www.ncbi.nlm.nih.gov/pubmed/26892497

Burger C, Nash KR. Small-Scale Recombinant Adeno-Associated Virus Purification. Methods in molecular biology (Clifton, N.J.). 1382: 95-106, 2016. http://www.ncbi.nlm.nih.gov/pubmed/26611581

Nash KR, Gordon MN. Convection Enhanced Delivery of Recombinant Adeno-associated Virus into the Mouse Brain. Methods in molecular biology (Clifton, N.J.). 1382: 285-95, 2016. http://www.ncbi.nlm.nih.gov/pubmed/26611595

Grewal R, Haghighi M, Huang S, Smith AG, Cao C, Lin X, Lee DC, Teten N, Hill AM, Selenica MB. Identifying biomarkers of dementia prevalent among amnestic mild cognitively impaired ethnic female patients. Alzheimers Res Ther 8(1): 43. 2016. https://www.ncbi.nlm.nih.gov/pubmed/27756387

Selenica MB, Reid P, Pena G, Alvarez J, Hunt JB, Nash KR, Morgan D, Gordon MN, Lee DC. Adeno associated viral-mediated intraosseous labeling of bone marrow derived cells for CNS tracking. Journal of immunological methods. , 2016. http://www.ncbi.nlm.nih.gov/pubmed/26784524

Grieco JC, Bahr RH, Schoenberg MR, Conover L, Mackie LN, Weeber EJ. Quantitative Measurement of Communication Ability in Children with Angelman Syndrome. Journal of applied research in intellectual disabilities : JARID. , 2016. http://www.ncbi.nlm.nih.gov/pubmed/27990716

Lussier AL, Weeber EJ, Rebeck GW. Reelin Proteolysis Affects Signaling Related to Normal Synapse Function and Neurodegeneration. Frontiers in Cellular Neuroscience. 10: 75, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27065802

Ciarlone SL, Grieco JC, D'Agostino DP, Weeber EJ. Ketone ester supplementation attenuates seizure activity, and improves behavior and hippocampal synaptic plasticity in an Angelman syndrome mouse model. Neurobiology of disease. 96: 38-46, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27546058

Ciarlone S L, and Weeber EJ. Towards targeted therapy for Angelman syndrome. Exp Opin on Orphan Drugs.. 4(3) : 317-325., 2016.

Ciarlone SL, Wang X, Rogawski MA, Weeber EJ. Effects of the synthetic neurosteroid ganaxolone on seizure activity and behavioral deficits in an Angelman syndrome mouse model.Neuropharmacology. 116: 142-150, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27986596

Grimmig B, Morganti J, Nash K, Bickford PC. Immunomodulators as Therapeutic Agents in Mitigating the Progression of Parkinson's Disease. Brain sciences. 6(4) , 2016. http://www.ncbi.nlm.nih.gov/pubmed/27669315

Zheng D, Sabbagh JJ, Blair LJ, Darling AL, Wen X, Dickey CA. MicroRNA-511 Binds to FKBP5 mRNA, Which Encodes a Chaperone Protein, and Regulates Neuronal Differentiation. The Journal of biological chemistry. 291(34) : 17897-906, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27334923

Lin L, Skakavac N, Lin X, Lin D, Borlongan MC, Borlongan CV, Cao C. Acupuncture-Induced Analgesia: The Role of Microglial Inhibition. Cell transplantation. 25(4) : 621-8, 2016. http://www.ncbi.nlm.nih.gov/pubmed/26849399

Sabbagh JJ, Fontaine SN, Shelton LB, Blair LJ, Hunt JB, Zhang B, Gutmann JM, Lee DC, Lloyd JD, Dickey CA. Noncontact Rotational Head Injury Produces Transient Cognitive Deficits but Lasting Neuropathological Changes. Journal of neurotrauma. 33(19) : 1751-1760, 2016. http://www.ncbi.nlm.nih.gov/pubmed/26739819

Andreasson KI, Bachstetter AD, Colonna M, Ginhoux F,et al. Targeting innate immunity for neurodegenerative disorders of the central nervous system. J Neurochem 138(5): 653-93. 2016. https://www.ncbi.nlm.nih.gov/pubmed/27248001

Narayan M, Kirouac L, Chaput D, Stevens S, Padmanabhan J, Jinwal U,K. Identification of Novel Cdc37 Interacting Proteins and Pathways in Human Alzheimer’s Disease Brain Tissue using Mass Spectrometry. Journal of Data Mining in Genomics & Proteomics. 7: 193, 2016.

Narayan M, Seeley K, W, Jinwal U, . ) Identification of Apo B48 and other novel biomarkers in amyotrophic lateral sclerosis patient fibroblasts. Biomarkers in Medicine. 10: 453-462, 2016. https://www.ncbi.nlm.nih.gov/pubmed/27141953

Narayan M, Seeley K, W, Jinwal U, K. Data from SILAC-based quantitative analysis of lysates from mouse microglial cells treated with Withaferin A (WA). Data in Brief. 7: 747-750, 2016. https://www.ncbi.nlm.nih.gov/pubmed/27054189

Klionsky D, J, …, , Jinwal U, K, …, , Zughaier S, M, et, al, . Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1 -222, 2016. https://www.ncbi.nlm.nih.gov/pubmed/26799652

Young ZT Rauch JN Assimon VA Jinwal UK, Ahn M Li X Dunyak BM Ahmad A Carlson GA Srinivasan SR Zuiderweg ER Dickey CA Gestwicki JE. Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy. Cell Chemical Biology. 23: 1-10, 2016. https://www.ncbi.nlm.nih.gov/pubmed/27499529

An SS, Mitzner W, Tang WY, Ahn K, Yoon AR, Huang J, Kilic O, Yong HM, Fahey JW, Kumar S, Biswal S, Holgate ST, Panettieri RA, Solway J, Liggett SB. An inflammation-independent contraction mechanophenotype of airway smooth muscle in asthma. The Journal of allergy and clinical immunology. 138(1) : 294-297.e4, 2016. http://www.ncbi.nlm.nih.gov/pubmed/26936804

Koziol-White CJ, Yoo EJ, Cao G, Zhang J, Papanikolaou E, Pushkarsky I, Andrews A, Himes BE, Damoiseaux RD, Liggett SB, Di Carlo D, Kurten RC, Panettieri RA. Inhibition of Phosphoinositide 3-Kinase (PI3K) promotes dilation of human small airways in a Rho kinase-dependent manner.British journal of pharmacology. , 2016. http://www.ncbi.nlm.nih.gov/pubmed/27352269

Kim D, Pauer SH, Yong HM, An SS, Liggett SB. β2-adrenergic Receptors Chaperone Trapped Bitter Taste Receptor 14 to the Cell Surface as a Heterodimer and Exert Unidirectional Desensitization of Taste Receptor Function. The Journal of biological chemistry. , 2016. http://www.ncbi.nlm.nih.gov/pubmed/27342779

Lin D, Wu Q, Lin X, Borlongan CV, He ZX, Tan J, Cao C, Zhou SF. Brain-derived Neurotrophic Factor Signaling Pathway: Modulation by Acupuncture in Telomerase Knockout Mice. Alternative therapies in health and medicine. 21(6) : 36-46. http://www.ncbi.nlm.nih.gov/pubmed/26567448

Hao Y, Bai G, Wang J, Zhao L, Sutherland K, Cai J, Cao C. Identifiable biomarker and treatment development using HIV-1 long term non-progressor sera. BMC immunology. 16: 25, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25927639

Blair LJ, Baker JD, Sabbagh JJ, Dickey CA. The emerging role of peptidyl-prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease. Journal of neurochemistry. 133(1) : 1-13, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25628064

Martin MD, Calcul L, Smith C, Jinwal UK, Fontaine SN, Darling A, Seeley K, Wojtas L, Narayan M, Gestwicki JE, Smith GR, Reitz AB, Baker BJ, Dickey CA. Synthesis, stereochemical analysis, and derivatization of myricanol provide new probes that promote autophagic tau clearance. ACS chemical biology. 10(4) : 1099-109, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25588114

Gamsby JJ Gulick D1. Chronic shifts in the length and phase of the light cycle increase intermittent alcohol drinking in C57BL/6J mice. Front Behav Neurosci. 9: 9, 2015.

Woo JA, Boggess T, Uhlar C, Wang X, Khan H, Cappos G, Joly-Amado A, De Narvaez E, Majid S, Minamide LS, Bamburg JR, Morgan D, Weeber E, Kang DE. RanBP9 at the intersection between cofilin and Aβ pathologies: rescue of neurodegenerative changes by RanBP9 reduction. Cell death & disease. 6: 1676, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25741591

Woo JA, Zhao X, Khan H, Penn C, Wang X, Joly-Amado A, Weeber E, Morgan D, Kang DE. Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers. Cell death and differentiation. , 2015. http://www.ncbi.nlm.nih.gov/pubmed/25698445

Fontaine SN, Rauch JN, Nordhues BA, Assimon VA, Stothert AR, Jinwal UK, Sabbagh JJ, Chang L, Stevens SM, Zuiderweg ER, Gestwicki JE, Dickey CA. Isoform-selective Genetic Inhibition of Constitutive Cytosolic Hsp70 Activity Promotes Client Tau Degradation Using an Altered Co-chaperone Complement. The Journal of biological chemistry. 290(21) : 13115-27, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25864199

DiBattista AM, Dumanis SB, Song JM, Bu G, Weeber E, Rebeck GW, Hoe HS. Very low density lipoprotein receptor regulates dendritic spine formation in a RasGRF1/CaMKII dependent manner. Biochimica et Biophysica Acta. 1853(5) : 904-17, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25644714

Hethorn WR, Ciarlone SL, Filonova I, Rogers JT, Aguirre D, Ramirez RA, Grieco JC, Peters MM, Gulick D, Anderson AE, L Banko J, Lussier AL, Weeber EJ. Reelin supplementation recovers synaptic plasticity and cognitive deficits in a mouse model for Angelman syndrome. The European Journal of Neuroscience. 41(10) : 1372-80, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25864922

Narayan M, Zhang J, Braswell K, Gibson C, Zitnyar A, Lee DC, Varghese-Gupta S, Jinwal UK. Withaferin A regulates LRRK2 levels by interfering with the Hsp90-Cdc37 chaperone complex.Current aging science. 8: 259-65, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25989799

Shahaduzzaman MD, Nash KR, Hudson C, Sharif M, Grimmig B, Lin X, Bai G, Liu H, Ugen KE, Cao C, & Bickford PC. Anti-human α-synuclein N-terminal peptide antibody protects against dopaminergic cell death and ameliorates behavioral deficits in an AAV-α-synuclein rat model of Parkinson’s Disease PLoS One. 10(2) : e0116841, 2015.

Hunt JB, Nash KR, Placides D, Moran P, Selenica ML, Abuqalbeen F, Ratnasamy K, Slouha N, Rodriguez-Ospina S, Savlia M, Ranaweera Y, Reid P, Dickey CA, Uricia R, Yang CG, Sandusky LA, Gordon MN, Morgan D, Lee DC. Sustained Arginase 1 Expression Modulates Pathological Tau Deposits in a Mouse Model of Tauopathy. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(44) : 14842-60, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26538654

Narayan M, Peralta DA, Gibson C, Zitnyar A, Jinwal UK. An optimized InCell Western screening technique identifies hexachlorophene as a novel potent TDP43 targeting drug. Journal of biotechnology. 207: 34-8, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25987361

Narayan M, Seeley K, W, Jinwal U, . Identification and Characterization of Cellular Proteins Affected by Treatment with Withaferin A using a SILAC-based Proteomics Approach. Journal of Ethnopharmacology. 175: 86-92, 2015.https://www.ncbi.nlm.nih.gov/pubmed/26392330

Ugen KE, Lin X, Bai G, Liang Z, Cai J, Li K, Song S, Cao C, Sanchez-Ramos J. Evaluation of an α synuclein sensitized dendritic cell based vaccine in a transgenic mouse model of Parkinson disease. Human vaccines & immunotherapeutics. 11(4) : 922-30, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25714663

Gamsby JJ, Gulick D. Chronic shifts in the length and phase of the light cycle increase intermittent alcohol drinking in C57BL/6J mice. Frontiers in Behavioral Neuroscience. 9: 9, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25691862

Hethorn WR, Ciarlone SL, Filonova I, Rogers JT, Aguirre D, Ramirez RA, Grieco JC, Peters MM, Gulick D, Anderson AE, L Banko J, Lussier AL, Weeber EJ. Reelin supplementation recovers synaptic plasticity and cognitive deficits in a mouse model for Angelman syndrome. The European Journal of Neuroscience. 41(10) : 1372-80, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25864922

Chau DT, Khokhar JY, Gulick D, Dawson R, Green AI. Desipramine enhances the ability of paliperidone to decrease alcohol drinking. Journal of Psychiatric Research. 69: 9-18, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26343589

Shahaduzzaman M, Nash K, Hudson C, Sharif M, Grimmig B, Lin X, Bai G, Liu H, Ugen KE, Cao C, Bickford PC. Anti-human α-synuclein N-terminal peptide antibody protects against dopaminergic cell death and ameliorates behavioral deficits in an AAV-α-synuclein rat model of Parkinson's disease. PloS one. 10(2) : e0116841, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25658425

Chu L, Zhao H, Fang J, Li C, Liu Z, Cui R, Hu F, Zhang X, Chen Y, Han H, Cao C, Xu Q. The traditional Chinese medicinal formula BDL301 suppresses tumor growth by inhibiting STAT3 pathway and inducing apoptosis in colorectal cancer cells. DNA and cell biology. 34(3) : 178-88, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25607688

Zhang LF, Zhou ZW, Wang ZH, Du YH, He ZX, Cao C, Zhou SF. Coffee and caffeine potentiate the antiamyloidogenic activity of melatonin via inhibition of Aβ oligomerization and modulation of the Tau-mediated pathway in N2a/APP cells. Drug design, development and therapy. 9: 241-72, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25565776

Cheng J, Zhou ZW, Sheng HP, He LJ, Fan XW, He ZX, Sun T, Zhang X, Zhao RJ, Gu L, Cao C, Zhou SF. An evidence-based update on the pharmacological activities and possible molecular targets of Lycium barbarum polysaccharides. Drug design, development and therapy. 9: 33-78, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25552899

Citron BA, Saykally JN, Cao C, Dennis JS, Runfeldt M, Arendash GW. Transcription factor Sp1 inhibition, memory, and cytokines in a mouse model of Alzheimer's disease. American journal of neurodegenerative disease. 4(2) : 40-8, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26807343

Cheng J, Lin X, Morgan D, Gordon M, Chen X, Wang ZH, Li HN, He LJ, Zhou SF, Cao C. Dendritic and Langerhans cells respond to Aβ peptides differently: implication for AD immunotherapy.Oncotarget. 6(34) : 35443-57, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26473448

Li Y, Wu H, Teng P, Bai G, Lin X, Zuo X, Cao C, Cai J. Helical Antimicrobial Sulfono-γ-AApeptides.Journal of medicinal chemistry. 58(11) : 4802-11, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26020456

Blair LJ, Frauen HD, Zhang B, Nordhues BA, Bijan S, Lin YC, Zamudio F, Hernandez LD, Sabbagh JJ, Selenica ML, Dickey CA. Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy. Acta neuropathologica communications. 3: 8, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25775028

Camoretti-Mercado B, Pauer SH, Yong HM, Smith DC, Deshpande DA, An SS, Liggett SB. Pleiotropic Effects of Bitter Taste Receptors on [Ca2+]i Mobilization, Hyperpolarization, and Relaxation of Human Airway Smooth Muscle Cells. PloS One. 10(6) : e0131582, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26121686

Bridges TM, Scheraga RG, Tulapurkar ME, Suffredini D, Liggett SB, Ramarathnam A, Potla R, Singh IS, Hasday JD. Polymorphisms in human heat shock factor-1 and analysis of potential biological consequences. Cell Stress Chaperones. 20(1) : 47-59, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25023647

Fox CS, Hall JL, Arnett DK, Ashley EA, Delles C, Engler MB, Freeman MW, Johnson JA, Lanfear DE, Liggett SB, Lusis AJ, Loscalzo J, MacRae CA, Musunuru K, Newby LK, O'Donnell CJ, Rich SS, Terzic A. Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association. Circulation. 131(19) : 1715-36, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25882488