Byrd Alzheimer’s Center and Research Institute

Welcome to the USF Health
Byrd Alzheimer’s Center and Research Institute

The USF Health Byrd Alzheimer’s Center and Research Institute is dedicated to the prevention, treatment and cure of Alzheimer’s disease and related disorders.

The institute is a multi-disciplinary center of excellence at the University of South Florida that provides compassionate family-centered patient care, performs cutting edge research and delivers quality public and professional education. With a state-of-the-art building and a highly qualified team of researchers, doctors, clinicians and educators, the institute is at the forefront of Alzheimer's research and care.

Key Activities

Laboratory Research

Clinical Trials

Family Caregiver Support

Professional Services

Byrd Investigator Dr. Alexa Woo launches a new NIH-funded research program

The Byrd Institute announces the award of a $1.8 million National Institutes of Health (NIH) grant to Jung A (Alexa) Woo, PhD, an Assistant Professor of Molecular Pharmacology and Physiology and a Byrd Investigator. Dr. Woo’s grant focuses on beta-arrestins, which are proteins classically known to bind and modify the function of cell surface receptors called GPCRs. Over the next five years, this grant will allow her to investigate how beta-arrestins alter the tau tangle protein to mitigate the pathogenesis of Alzheimer’s disease (AD), possibly leading to new AD therapies.

Interview with Dr. Laura Blair featured by eNeuro Press

The April 2019 issue of the eNeuro Journal an official online scientific journal for the Society for Neuroscience, has featured an interview with Dr. Laura Blair, a Byrd investigator. In the interview, Dr. Blair talks about her recent publication in eNeuro describing the cellular and behavioral deficits in a transgenic mouse model in which the FKBP5 gene is overexpressed. Increased FKBP5 has been associated with several psychiatric disorders. The interview goes on to describe her research philosophy and the focus of her laboratory. Full detailed transcript of the interview and paper can be found here.

Byrd Institute welcomes new researcher

Dr. Lianchun Wang recently joined the Byrd Institute as a Professor of Molecular Pharmacology & Physiology. His research focuses on heparan sulfate (HS), a linear sugar present at the surface of cells and extracellular matrix. He has worked to understand the functions and related structures of HS in inflammation, blood vessel development, cancer, and stem cell biology. Dr. Wang’s research also extends to Alzheimer’s, with a focus on the aberrant expression of HS as a potential biomarker for the diagnosis and prognosis of the disease. This NIH-funded research examines the role of HS in the regulation of amyloid beta metabolism and neuroinflammation attributing to the pathogenesis of Alzheimer’s.

Dr. Krishna Bhat launches NIH-funded research program

We are excited to announce a $1.5 million research grant from the National Institutes of Health (NIH) awarded to Krishna Bhat, MD, PhD, Professor of Molecular Medicine and Byrd Institute Investigator. This grant will allow him to conduct research on genes and proteins that regulate the division of neuronal stem cells. His findings could reveal how the brain is formed during development and provide key insights to new therapies that induce the generation of new brain cells in the adult brain. This could help treat many degenerative conditions of the brain, including Alzheimer’s.

Clinical Research Challenges

Dr. Amanda Smith, Director of Clinical Research at the Byrd Institute, discussed difficulties faced when trying to enroll people into clinical studies. Transportation concerns and fear of the unknown sometimes keep people away. These obstacles are problematic because the need for clinical trials participants has never been greater. See the article on TampaBay.com to learn more.

Welcome

On behalf of the University of South Florida’s Morsani College of Medicine and the USF Health Neuroscience Institute, welcome to the Byrd Alzheimer’s Center and Research Institute website. Throughout these pages, we hope that you will find inspiration, direction and hope from the work that our team is doing in our laboratories, through our clinical trials programs and with our community educational services.