Currently, there are very few treatment options for those with Alzheimer’s disease (AD). Clinical trials are the only way for new treatments to be developed that can prevent progression of the disease. Clinical trials also help us learn more about AD. At the Byrd Institute, we are involved in several research studies, adding new studies regularly. We offer a range of participation options including prevention studies for older people without memory loss and studies that include treatment of mild cognitive impairment (MCI) and mild to moderate AD. Some of our trials are observation-only, while others involve pills, injections, or infusions. Additionally, many trials include special blood tests, cognitive testing, and brain imaging (PET scans) to detect the protein accumulation associated with memory loss. Below is a list of opportunities to participate in our studies.

The Byrd Institute is very pleased to announce a new study
we are currently conducting that is aimed to delay or prevent Alzheimer's. 

Please read this article for more information .

 

Currently Enrolling Clinical Trials

> For Individuals WITH Memory Loss

• A 2.5-year confirmatory trial to verify the clinical benefit of aducanumab compared with placebo in participants with Alzheimer’s disease. This study is for patients 60-85 years old with mild cognitive impairment due to Alzheimer’s disease or mild Alzheimer’s disease. 

• A 20.5-month trial investigating an oral treatment which may slow the progression of symptoms of early Alzheimer’s disease. This study is for patients 50-89 years old with mild cognitive impairment due to Alzheimer’s disease or mild Alzheimer’s disease.

> For Individuals WITHOUT Memory Loss

• A 5-year study involving cognitive testing and neuroimaging, which is intended to help recruit for future Alzheimer's prevention studies. This study is for individuals 50-85 years old who currently have no memory problems.
  
  
•  A 4-year “prevention” study investigating an infusion-based treatment that may reduce amyloid plaque in the brain. This study is for individuals 55-80 years old who currently have no memory problems. 

 

Upcoming Clinical Trials

 > For Individuals WITH Memory Loss

• A multi-year observational study involving cognitive testing and neuroimaging, which may help to learn more about Alzheimer’s disease.
               
• A 72-week trial investigating two doses of an oral treatment which may improve cognition and function in patients with early Alzheimer’s disease. This study is for patients 50-85 years old with mild cognitive impairment due to Alzheimer’s disease or mild Alzheimer’s disease.

> For Individuals WITHOUT Memory Loss

•  A multi-year observational study involving cognitive testing and neuroimaging, which may help to learn more about Alzheimer’s disease.

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We always have new trials just around the corner. Please check back with us for updates!

For more information about our clinical research, contact
Anna Sladky at (813) 974-4904 or asladky@usf.edu

Links for Finding Clinical Trials

• Alzheimer's Association
• National Institutes of Health
• USF Cognitive Aging Lab