USF Institute on Microbiomes

Microbiome Research Award 2021

Ignite Award

This award is intended to accelerate progress for microbiome research projects. These awards are intended to be small, rapid-access awards to 1) help investigative teams maintain momentum on feasibility projects with high probability of traversing research gaps related to microbiome research, 2) obtain pilot data that will allow for the submission of a subsequent, larger extramural grant application, or 3) provide internal funding for new research projects that have been peer-reviewed and scored to help move grants to a fundable range. Funds will be awarded for up to $5,000 to be spent within a maximum of 3 months.  Applications are accepted on a rolling monthly basis. 

Click HERE for the full announcement. 


Past Awards

External Funding Opportunities

Below is a list of external grant opportunities in the field of microbiomes.  They include grants that specifically support microbiome research, as well as those that, while not microbiome-specific, would certainly be applicable.  

If you see a microbiomes-related funding opportunity that is not listed here, please send it to and it will be added to the list. 

(Click on each category to expand.)

  • National Institutes of Health (NIH)

    Notice of Special Interest (NOSI): The Functional Oral Microbiome

    Due Date: February 5, 2022
    For more information:   

    Notice of Special Interest: Development of Swallowable Smart Pills or Devices for Precision Nutrition, Microbiome and Digestive Disease Applications

    Due Date: January 08, 2023
    For more information:

    Notice of Special Interest (NOSI): Methods Development in Natural Products Research (SBIR/STTR)

    Due Date: September 05, 2023
    For more information: 

    Identification and Characterization of Bioactive Microbial Metabolites for Advancing Research on Microbe-Diet-Host Interactions (R01 Clinical Trial Not Allowed)

    FOA Number: PAR-21-253
    Due Date:  May 20, 2022
    For more information:

    Prevention Research in Mid-Life Adults (R01 Clinical Trial Optional)

    FOA Number: PA-18-849
    Due Date: Standard dates apply.
    Relevance to Microbiomes: "Research projects of interest include, but are not limited to, those that:...Elucidate how age-related perturbations in the microbiome influence biological processes that predispose mid-life adults to chronic illness; develop and test interventions that shift the microbiome toward a protective state."
    For more information: 

    Modulating Human Microbiome Function to Enhance Immune Responses Against Cancer (R01 Clinical Trial Not Allowed)

    FOA Number: PAR-22-061
    Due Date: January 05, 2022
    For more information:

    Development of Microbiome-Related Approaches for Diagnosis/Mitigation/Treatment of Radiation Injuries (U01 Clinical Trial Not Allowed)

    FOA Number: RFA-AI-21-068
    Due Date: February 09, 2022 (LOI due 30 days prior)
    For more information:

    NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed)

    FOA Number: PAR-20-060
    Due Date: Standard dates apply. 
    Relevance to Microbiomes: "Examples of studies that might be supported by this FOA include, but are not limited to:...Applications of cohort studies assessing associations of psychosocial and behavioral factors with -omics changes (including epigenetic modifications to the human genome and/or oral microbiome alterations) and impact of the associations upon oral diseases and conditions.  Applications of cohort studies that analyze interaction of the human genome and oral microbiome in response to environmental stimuli and impact of the interaction on oral diseases and conditions."
    For more information

    Development of the Fetal Immune System (R01 Clinical Trial Not Allowed)

    FOA Number: PAR-20-298
    Due Date: December 7, 2021
    Expiration Date: December 08, 2023
    Relevance to Microbiomes: "The scope of this FOA can be covered under these following broad topics and is not limited to:  Understand the contribution of specific elements of materno-fetal milieu that can control and affect secondary lymphoid system development and homeostasis leading to commensal microbiome fitness in the fetus and early infancy."

    "Applications not responsive to this FOA will not be reviewed....Applications proposing to focus exclusively on effects of maternal microbiome and not studying the relevance of these effects on fetal immune system development."
    For more information:

    New Research Directions that Advance the NHLBI Strategic Vision Normal Biology (R21 - Clinical Trial Not Allowed)

    FOA Number: PA-19-049
    Due Date: Standard dates apply.  
    Expiration Date:  January 8, 2022
    Relevance to Microbiomes: Specific areas of research interest include: "Determining the influence of the microbiome (including virome and fungome) on the immune system and on HLBS health and resilience, including developmental processes, across the lifespan."
    For more information

    Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of the NIDDK (R21 Clinical Trial Not Allowed)

    FOA Number: PAR-21-062
    Due Date: Standard AIDS dates apply. 
    Relevance to Microbiomes: “The scope of this FOA includes but is not limited to: The impact of HIV or its treatment on the gastrointestinal or penile microbiome, pathogenic enteric microbes, male genital tract infections, or co-infection with hepatitis viruses.”
    For more information:

    Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)

    Funding Opportunity Announcement (FOA) Number: PAR-21-233
    Due Dates: February 9, 2022, August 9, 2022, February 9, 2023, August 9, 2023, February 9, 2024 (Letter of Intent due 30 days prior to due date).
    Relevance to Microbiomes: “This Funding Opportunity Announcement (FOA) supports preclinical discovery and development of potential therapeutic Biotechnology Products and Biologics including, but not limited to, large biologic macromolecules, (e.g., proteins, antibodies, and peptides), gene-based therapies (i.e., oligonucleotide- and viral-based), cell therapies, and novel emerging therapies (e.g., microbial and microbiome therapies).”
    For more information: 

    Microbial-based Cancer Therapy -Bugs as Drugs (R01 Clinical Trial Not Allowed)

    Notice Number: PAR-19-193
    Due Dates: Standard dates apply. Expiration date: May 8, 2022
    For more information
    R-21 also available 

    Notice of Special Interest (NOSI): Investigations on Inborn Errors of Immunity/Primary Immunodeficiencies Notice Number: NOT-AI-21-032

    Due Date: May 07, 2024 
    Relevance to Microbiomes: “Research areas supported by this NOSI include,but are NOT limited to…Investigating the role of gut microbiome in the pathogenesis of inborn errors of immunity.”
    For more information

  • National Science Foundation (NSF)

    Division of Molecular and Cellular Biosciences: Investigator-initiated research projects (MCB)

    Funding Opportunity Number:  NSF 18-585
    Due Date: Continuous
    Anticipated Funding Amount: $90,000,000 Pending availability of funds, approximately $90M will be committed for the total budget of all new awards in each fiscal year.  
    For more information:

    Division of Integrative Organismal Systems Core Programs

    Due Dates:  Continuous
    Anticipated Funding Amount: $60,000,000 IOS estimates that approximately $60,000,000 will be available for new and continuing awards per fiscal year. Estimated program budget, number of awards and average award size/duration are subject to the availability of funds.
    For more information

    Disability and Rehabilitation Engineering (DARE)

    Notice Number:  PD 20-5342
    Due Dates:  Continuous 
    For more information:

    Cellular and Biochemical Engineering

    Notice Number: PD 20-1491
    Due Date:  Continuous
    For more information:

    Engineering of Biomedical Systems

    Notice Number: PD 20-5345
    Due Date:  Continuous.
    For more information:  

    Plant Biotic Interactions

    Notice Number: NSF 18-590
    Due Date:  Continuous.
    Approximate Funding Amount: $18,500,000 depending on availability of funds$10.5M from NSF for new standard or continuing grant awards, and approximately $8M from USDA/NIFA for new awards. Both estimates depend on availability of appropriations. USDA/NIFA will support projects for up to four years in duration. Although there are no formal upper or lower limits to award amounts, they typically range from $50,000 to $300,000 per year, with durations of two to four years (and five years for CAREER awards). Enactment of additional continuing resolutions or an appropriations act may affect the availability or level of funding for this program.
    For more information: 

    Transitions to Excellence in Molecular and Cellular Biosciences Research (Transitions) 

    Notice Number: NSF 21-508
    Due Date:  Continuous.  
    Anticipated Funding Amount: $6,000,000 Pending availability of funds
    For more information:  

     Engineering of Biomedical Systems

    Notice Number: PD 20-5345
    Due Date: Continuous
    For more information:


  • United States Department of Agriculture (USDA)

    Agriculture and Food Research Initiative - Foundational and Applied Science Program - Crosscutting Programs - Agricultural Microbiomes in Plant Systems and Natural Resources

    Deadline: October 6, 2022
    For more information:

    ERDC Broad Agency Announcement - Biogeochemical Processes in Earth Materials Technical Area (CRREL-3)

    Deadline:  February 28, 2022
    For more information

  • Department of Defense (DOD)

    US Army Combat Capabilities Development Command Broad Agency Announcement

    Issued by: Department of Defense
    Due Date(s): Feb 28, 2025
    Funding Opportunity Number: W911QY20R0022
    For more information:

  • Private / Foundations

    NOSTER & Science Microbiome Prize 

    Sponsor: American Association for the Advancement of Science
    Due Date: January 24, 2022
    For more information:

    American Gastroenterological Association Grants

    Due Date: Varies
    For list of Grants

    Grants for Research in the Life Sciences

    Sponsor: G. Harold and Leila Y. Mathers Charitable Foundation
    Relevance to Microbiomes: "The foundation is primarily interested in supporting immunology, microbiome, genomics, structural biology, cellular physiology, neuroscience, etc. are some noteworthy examples of current research support. The Foundation primarily supports basic science, ideally with potential translational applications. The Foundation does not support clinical or drug discovery." Application
    Due Date: Continuous
    For more information