MCOM Labs Directory
Espana Lab
The Espana Corneal Extracellular Matrix Laboratory
We investigate corneal biology by creating corneal wounds in different mouse models, deficient or inducible in different types of collagens, cell cultures, molecular biology techniques and advanced microscopy techniques including electron microscopy, second harmonics, live in vivo confocal microscopy and regular confocal microscopy. The long term goal is to modulate wound healing and scar formation to maintain corneal transparency.
Laboratory Areas of Interest
- Regulation of structure and function by FACIT collagens.
- Regulation of stromal regeneration by collagens V and XII.
- Regulation of the Posterior Stroma-Endothelial niche by the extracellular matrix.
Publications
View our publications on PubMed.
Lab Members
Sheila Adams
Mei Sun
Devon Cogswell
Research Associate
I cut(cryosection) and stain tissue with antibodies for immunofluorescence, assist in surgeries on the mice, culture primary and immortalized cell lines for experiments like luciferase assays, cell migration studies, and cell staining for immunofluorescence. My current interest in the lab is to elucidate the role of Collagen V fragments after injury.
Thomas A. Weppelmann
Cornea Fellow
