CONCLUSIONS: Prior studies have indicated that metabolic and bariatric surgery is effective in treating class III obesity and the decline of co-morbidities. Here, we show that the benefits of metabolic and bariatric surgery on diabetes and HLD are enhanced with preoperative weight loss in the immediate postoperative period. Understanding these changes in co-morbidities after surgery will be important in effectively advising patients on preoperative weight loss and helping them manage their...

CONCLUSION: This case highlights the need for careful evaluation of cervical spine instability in pediatric patients with motor delay. Neurosurgeons should avoid prematurely attributing deficits to cerebral palsy or underlying syndromic disorders and should maintain a high index of suspicion for potentially reversible cervical pathology. Early diagnosis and surgical treatment can lead to substantial neurological recovery.

BACKGROUND: Efgartigimod is a human immunoglobulin (IgG1) antibody Fc fragment that reduces IgG levels through neonatal Fc receptor blockade. ADAPT-SC+ assessed the long-term safety, tolerability, and efficacy of subcutaneous (SC) efgartigimod PH20 in adult participants with generalized myasthenia gravis (gMG). Previously, ADAPT-SC demonstrated noninferiority of efgartigimod PH20 SC to intravenous efgartigimod.

One of the great advancements in ophthalmic surgery during the 20th century was the development of the artificial intraocular lens (IOL). There is remarkably little historical information on the trends in IOL innovation based on what inventors believed was worthy of patent protection in the United States (U.S.). We explored the topic of patentable IOL innovations by obtaining information through a global patent database. Patents issued for IOLs in the U.S. during the 20th century were...