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Otolaryngology - Head & Neck Surgery

Head and Neck Surgical Oncology


Head and neck cancers are a diverse group of diseases that affect the mouth, throat, voice box, salivary glands, nose, sinuses, skin, thyroid, and other structures of the head and neck. Many of these conditions are uncommon and often benefit from treatment at a specialized academic cancer center. 

The USF Health Head and Neck Cancer Program, in partnership with Tampa General Hospital, provides comprehensive care for patients with head and neck cancers as well as complex benign conditions, including thyroid disease, salivary gland tumors, neck masses, and skull base disorders. Our fellowship-trained surgeons offer expertise in advanced cancer surgery, minimally invasive techniques, robotic surgery, skull base surgery, and complex reconstruction aimed at restoring function and quality of life after treatment. 

Highlights of our program 

  • Multidisciplinary care in coordination with the TGH Cancer Institute 

  • Transoral robotic surgery (TORS) and other minimally invasive techniques 

  • Expertise in thyroid, parotid, and salivary gland surgery 

  • Advanced microvascular and other reconstructive techniques 

  • Access to clinical trials and emerging therapies 

  • Comprehensive speech, swallowing, nutrition, rehabilitation, and survivorship services 

Comprehensive care from diagnosis through survivorship 

Every patient's cancer is unique. Treatment options continue to evolve and may include surgery, radiation therapy, chemotherapy, immunotherapy, targeted therapy, or a combination of these approaches. At USF Health and Tampa General Hospital, patients have access to established treatments as well as emerging therapies and clinical trials when appropriate. Our team continuously evaluates new evidence and treatment advances to ensure patients receive the highest standard of care. 

Head and neck cancers can affect speaking, swallowing, breathing, nutrition, appearance, and many aspects of daily life. Because of this, effective treatment requires a coordinated team of specialists focused on every stage of care. 

The USF Health and Tampa General Head and Neck Program brings together head and neck surgeons, medical oncologists, radiation oncologists, radiologists, pathologists, speech-language pathologists, nutrition specialists, rehabilitation providers, nurse navigators, and supportive care teams within a single integrated academic health system. The close integration of our surgical, medical, radiation, rehabilitation, and supportive care teams allow patients to receive comprehensive cancer care within one coordinated program. 

In addition to cancer treatment, patients have access to specialized speech and swallowing rehabilitation, nutrition support, reconstructive surgery, survivorship resources, and clinical trials throughout their care journey. 

From diagnosis through treatment, recovery, and survivorship, our team works together to create a personalized care plan focused not only on achieving the best possible cancer outcomes, but also on preserving speech, swallowing, appearance, nutrition, and overall quality of life. 

Whether treatment involves surgery, radiation, chemotherapy, immunotherapy, or a combination of therapies, patients benefit from coordinated care delivered across the full continuum of cancer treatment and recovery. 

Grateful Patient Stories

USF Health doctor saves a child's life with a rare head and neck cancer

For most children, a loose tooth usually means a visit from the Tooth Fairy. But for Aubrey Romero of Bradenton, it was a sign of something more serious, cancer.

Aubrey, 8, had Odontogenic Ghost Cell Carcinoma, a very rare head and neck cancer. Less than 100 cases have been documented in the last 50 years and almost none involved children.

USF physicians treat an aggressive ENT cancer for car enthusiast

Allen Parent, of Brookville, Fla., was diagnosed with squamous cell mouth cancer, a head and neck cancer, and referred for treatment to Dr. Matthew Mifsud, a USF Health head and neck surgeon and otolaryngologist, and Dr. Julia Toman, a USF Health facial plastic surgeon. Watch to see Mr. Parent's journey from cancer diagnosis, to treatment and to the removal of his scars from the treatments.

Conditions, treatments and care

Head and neck cancers 

  • Oral cavity cancer (tongue, gums, floor of mouth, cheek, and palate) 

  • HPV-related throat cancer (oropharyngeal cancer) 

  • Laryngeal and hypopharyngeal cancer 

  • Nasopharyngeal cancer 

  • Nasal cavity and sinus cancer 

  • Salivary gland cancer 

  • Thyroid cancer 

  • Advanced skin cancer and melanoma involving the head, face, and neck 

  • Sarcomas and other rare head and neck tumors 

  • Recurrent head and neck cancer 

  • Cancer that has spread to lymph nodes in the neck 

Benign and complex head and neck conditions 

  • Thyroid nodules and thyroid tumors 

  • Parotid and salivary gland tumors 

  • Neck masses and enlarged lymph nodes 

  • Congenital neck cysts and developmental neck masses 

  • Osteoradionecrosis and osteomyelitis of the jaw 

  • Benign tumors of the mouth, neck, and salivary glands 

  • Vascular malformations and vascular tumors 

  • Skull base tumors 

  • Facial and jaw conditions requiring reconstruction 

We provide the following treatments:

  • Thyroid surgery and thyroidectomy 

  • Minimally invasive parotidectomy and salivary gland surgery 

  • Surgical treatment of oral cavity, tongue, jaw, and throat cancers 

  • Transoral robotic surgery (TORS) 

  • Laser surgery for selected head and neck tumors 

  • Neck dissection and lymph node surgery 

  • Sentinel lymph node biopsy for selected cancers 

  • Skull base and sinonasal tumor surgery 

  • Mandibular and maxillary reconstruction 

  • Microvascular free-flap reconstruction 

  • Facial and soft tissue reconstruction 

  • Treatment of recurrent and previously treated head and neck cancers 

  • Surgery for complex benign tumors and neck masses 

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For more questions about care or to schedule an appointment by phone, please call: (813) 821-8029.