Clinical Research

Our physicians and support staff work tirelessly to ensure safety and efficacy of medication and other treatment regimens meant to prevent and treat diseases in the pediatric and adolescent population.

Below, please find some highlights from the clinical research happening in our divisions.

  •  For more information on HOT DOCS and DOCS K-5, visit

    • Claudia Espinosa, MD, MSc: Her research interests include perinatal infections, surveillance of respiratory infections, and infection prevention. 

      She is currently PI for the following studies:

      1. A neonatal enterovirus ad human parechovirus viral sepsis study to define the natural history and predictors of morbidity and mortality of these infections in neonates NIAID/University Cincinnati
      2. A prospective study of Acute Flaccid Myelitis to define natural history, risk factors, and pathogenic mechanisms of this disease. UAB/NIH
      3. A phase 2 randomized, double blind, placebo-controlled, study to evaluate an antiviral in children infected with RSV
      4. A phase 3, multicenter, randomized, partially blinded, palivizumab controlled study to evaluate the safety, efficacy, and pharmacokinetics of a monoclonal antibody in infants and children at increased risk for severe RSV disease
      5. A phase 2 open-label, uncontrolled, single-dose study to evaluate the safety and tolerability, pharmacokinetics, occurrence of antidrug antibody, and efficacy of nirsevimab in immunocompromised children who are ≤ 24 months of age at the time of dose administration