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* (OBGYN Education & Research Profile)

Umit Kayisli, MSc, PhD

Umit Kayisli, MSc, PhD

Professor, Obstetrics and Gynecology

Contact Info

  • 12901 Bruce B Downs Blvd
    Tampa FL 33612
  • Academic Email:
  • Academic Phone: 8139743192
  • View My C.V.


  • PhD, Histology and Embryology, Akdeniz University, 2003

Interdisciplinary and Emerging Signature Programs

  • Women & Children's Health

Recent Publications

  • Shapiro JP, Guzeloglu-Kayisli O, Kayisli UA, Semerci N, Huang SJ, Arlier S, Larsen K, Fadda P, Schatz F, Lockwood CJ. Thrombin impairs human endometrial endothelial angiogenesis; implications for progestin-only contraceptive-induced abnormal uterine bleeding. Contraception. 95(6) : 592-601, 2017.
  • Yen CF, Kim SH, Liao SK, Atabekoglu C, Uckac S, Arici A, Arlier S, Lee CL, Wang HS, Kayisli UA. Increased expression of integrin-linked kinase during decidualization regulates the morphological transformation of endometrial stromal cells. Fertility and sterility. 107(3) : 803-812, 2017.
  • Yen CF Liao SK Huang SJ Tabak S Arcuri F Lee CL Arici A Petraglia F Wang HS and Kayisli UA. Decreased Endometrial Expression of Leukemia Inhibitory Factor Receptor Disrupts the STAT3 Signaling in Adenomyosis During the Implantation Window. Reprod. Sci.. 1: 1933719116681515. doi: 10.1177/1933719116681515., 2017.
  • Schatz F, Guzeloglu-Kayisli O, Arlier S, Kayisli UA, Lockwood CJ. The role of decidual cells in uterine hemostasis, menstruation, inflammation, adverse pregnancy outcomes and abnormal uterine bleeding. Human reproduction update. 22(4) : 497-515, 2016.
  • Yen CF, Liao SK, Huang SJ, Tabak S, Arcuri F, Lee CL, Arici A, Petraglia F, Wang HS, Kayisli UA. Decreased Endometrial Expression of Leukemia Inhibitory Factor Receptor Disrupts the STAT3 Signaling in Adenomyosis During the Implantation Window. Reproductive sciences (Thousand Oaks, Calif.). : 1933719116681515, 2016.
  • Guzeloglu-Kayisli O, Kayisli UA, Semerci N, Basar M, Buchwalder LF, Buhimschi CS, Buhimschi IA, Arcuri F, Larsen K, Huang JS, Schatz F, Lockwood CJ. Mechanisms of chorioamnionitis-associated preterm birth: interleukin-1β inhibits progesterone receptor expression in decidual cells. The Journal of pathology. 237(4) : 423-34, 2015.
  • Guzeloglu Kayisli O, Kayisli UA, Basar M, Semerci N, Schatz F, Lockwood CJ. Progestins Upregulate FKBP51 Expression in Human Endometrial Stromal Cells to Induce Functional Progesterone and Glucocorticoid Withdrawal: Implications for Contraceptive- Associated Abnormal Uterine Bleeding. PloS one. 10(10) : e0137855, 2015.
  • Schatz F, Guzeloglu-Kayisli O, Basar M, Buchwalder LF, Ocak N, Guzel E, Guller S, Semerci N, Kayisli UA, Lockwood CJ. Enhanced Human Decidual Cell-Expressed FKBP51 May Promote Labor-Related Functional Progesterone Withdrawal. The American journal of pathology. 185(9) : 2402-11, 2015.
  • Kayisli UA, Basar M, Guzeloglu-Kayisli O, Semerci N, Atkinson HC, Shapiro J, Summerfield T, Huang SJ, Prelle K, Schatz F, Lockwood CJ. Long-acting progestin-only contraceptives impair endometrial vasculature by inhibiting uterine vascular smooth muscle cell survival. Proceedings of the National Academy of Sciences of the United States of America. 112(16) : 5153-8, 2015.
  • Cetinkaya BO, Pamuk F, Keles GC, Ayas B, Ozfidan GK, Kayisli U, Arik N, Horton H. The role of phosphatase and tensin homolog in drug-induced gingival overgrowth. Journal of Periodontal Research. 49(3) : 307-13, 2014.
  • Doherty LF, Martin JR, Kayisli U, Sakkas D, Patrizio P. Fresh transfer outcome predicts the success of a subsequent frozen transfer utilizing blastocysts of the same cohort. Reproductive Biomedicine Online. 28(2) : 204-8, 2014.
  • Lockwood CJ, Huang SJ, Chen CP, Huang Y, Xu J, Faramarzi S, Kayisli O, Kayisli U, Koopman L, Smedts D, Buchwalder LF, Schatz F. Decidual cell regulation of natural killer cell-recruiting chemokines: implications for the pathogenesis and prediction of preeclampsia. The American Journal of Pathology. 183(3) : 841-56, 2013.
  • Kayisli UA, Guzeloglu-Kayisli O, Guzel E, Arici A. Genistein inhibits cell proliferation and stimulates apoptosis in human coronary artery endothelial cells. Gynecologic and Obstetric Investigation. 75(4) : 235-42, 2013.
  • Lockwood CJ, Kayisli UA, Stocco C, Murk W, Vatandaslar E, Buchwalder LF, Schatz F. Abruption-induced preterm delivery is associated with thrombin-mediated functional progesterone withdrawal in decidual cells. The American Journal of Pathology. 181(6) : 2138-48, 2012.
  • Fragouli E, Wells D, Iager AE, Kayisli UA, Patrizio P. Alteration of gene expression in human cumulus cells as a potential indicator of oocyte aneuploidy. Human Reproduction (Oxford, England). 27(8) : 2559-68, 2012.
  • Schatz F, Kayisli UA, Vatandaslar E, Ocak N, Guller S, Abrahams VM, Krikun G, Lockwood CJ. Toll-like receptor 4 expression in decidual cells and interstitial trophoblasts across human pregnancy. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 68(2) : 146-53, 2012.
  • Ucar AY, Kayisli UA, Demir N. The c-Abl expression in uterine epithelium during the mouse estrus cycle. Journal of Molecular Histology. 43(1) : 107-13, 2012.
  • Guzel E, Basar M, Ocak N, Arici A, Kayisli UA. Bidirectional interaction between unfolded-protein-response key protein HSPA5 and estrogen signaling in human endometrium. Biology of Reproduction. 85(1) : 121-7, 2011.
  • Yaba A, Kayisli UA, Johnson J, Demir R, Demir N. The Abelson tyrosine kinase (c-Abl) expression on the mouse uterus and placenta during gestational period. Journal of Molecular Histology. 42(2) : 91-6, 2011.
  • Fischer CP1 Kayisli U Taylor HS. HOXA10 expression is decreased in endometrium of women with adenomyosis. Fertil Steril.. 95(3) : 1133-1136, 2011.
  • Karipcin FS, Ensari TA, Kayisli UA, Guzel E, Kallen CB, Seli E. The mRNA-binding protein HuR is regulated in the menstrual cycle and repressed in ectopic endometrium. Reproductive Sciences (Thousand Oaks, Calif.). 18(2) : 145-55, 2011.
  • Uz YH, Murk W, Bozkurt I, Kizilay G, Arici A, Kayisli UA. Increased c-Jun N-terminal kinase activation in human endometriotic endothelial cells. Histochemistry and Cell Biology. 135(1) : 83-91, 2011.
  • Uz YH, Murk W, Yetkin CE, Kayisli UA, Arici A. Expression and role of interleukin-23 in human endometrium throughout the menstrual cycle and early pregnancy. Journal of Reproductive Immunology. 87(1) : 21-7, 2010.
  • Basar M, Yen CF, Buchwalder LF, Murk W, Huang SJ, Godlewski K, Kocamaz E, Arda O, Schatz F, Lockwood CJ, Kayisli UA. Preeclampsia-related increase of interleukin-11 expression in human decidual cells. Reproduction (Cambridge, England). 140(4) : 605-12, 2010.
  • Lockwood CJ, Murk WK, Kayisli UA, Buchwalder LF, Huang SJ, Arcuri F, Li M, Gopinath A, Schatz F. Regulation of interleukin-6 expression in human decidual cells and its potential role in chorioamnionitis. The American Journal of Pathology. 177(4) : 1755-64, 2010.
  • Lockwood CJ, Stocco C, Murk W, Kayisli UA, Funai EF, Schatz F. Human labor is associated with reduced decidual cell expression of progesterone, but not glucocorticoid, receptors. The Journal of Clinical Endocrinology and Metabolism. 95(5) : 2271-5, 2010.
  • Luk J Seval Y Ulukus M Ulukus EC Arici A Kayisli UA. Regulation of monocyte chemotactic protein-1 expression in human endometrial endothelial cells by sex steroids: a potential mechanism for leukocyte recruitment in endometriosis. Reprod Sci. 17(3) : 278-87, 2010.