USF Heart Institute
Travis Jackson, Ph.D.
Associate Professor, College of Medicine Molecular Pharmacology & Physiology
Contact Info
12901 Bruce B Downs BLVD
Tampa FL 33612
Academic Email: tcjackson@usf.edu
Academic Phone:(813) 974-2899
Education
- PhD, Biomedical Science, University of Florida, 2010
- BS, Neuroscience, University of Pittsburgh, 2005
Interdisciplinary and Emerging Signature Programs
- Allergy, Immunology & Infectious Disease
- Cardiovascular Sciences
- Cellular and Molecular Biology
- Neuroscience
Research Interests
- My laboratory uses in vitro and in vivo models of acute CNS injury to investigate novel cell signaling mechanisms contributing to axonal and neuronal damage in the brain. We use transgenic mice, lentivirus-based approaches, and experimental small-molecule drugs to study potential neuroprotective therapies. Germane to specific targets of interest, we are currently funded by the National Institute of Neurological Disorders and Stroke (NINDS) on a project to elucidate the role of the pro-death splicing factor RNA binding motif 5 (RBM5) in traumatic brain injury (TBI). In addition, my laboratory is developing potential strategies to enhance the neuroprotective efficacy of therapeutic hypothermia (TH). Namely, we are investigating methods to optimize the induction of cold-shock proteins (CSPs) and cold-stress hormones (CSHs), to increase the benefits of cerebroprotective cooling.
Recent Publications
- Jackson TC, Herrmann JR, Garman RH, Kang RD, Vagni VA, Gorse K, Janesko-Feldman K, Stezoski J, Kochanek PM Hypoxia-ischemia-mediated effects on neurodevelopmentally regulated cold-shock proteins in neonatal mice under strict temperature control Pediatric Research. , 2022.
- Farooq J Snyder K, Janesko-Feldman K, Gorse K, Vagni V, Kochanek PM, Jackson T RNA Binding Motif 5 Gene Deletion Modulates Cell Signaling in a Sex-Dependent Manner but not Hippocampal Cell Death J Neurotrauma. , 2022.
- Jeremy R, Herrmann Ericka L, Fink Anthony Fabio Alicia K, Au Rachel P, Berger Keri Janesko-Feldman Robert S, B, Clark Patrick M, Kochanek Travis C, Jackso. Serum levels of the cold stress hormones FGF21 and GDF-15 after cardiac arrest in infants and children enrolled in single center therapeutic hypothermia clinical trials Advanced Online Publication. , 2021.
- Jackson T, C, Gorse K, Herrmann J, R, et al, . Hippocampal and Prefrontal Cortical Brain Tissue Levels of Irisin and GDF15 Receptor Subunits in Children Mol Neurobiol. , 2021.
- Travis C, Jackson Keri Janesko-Feldman Shaun W Carlson Shawn E Kotermanski Patrick M Kockanek. Robust RBM3 and β-klotho expression in developing neurons in the human brain Sage Journals. , 2019.