Welcome to the USF Health
- We focus on the mechanistic understanding of cardiac normal and abnormal electrical impulse propagation. We strive to further explore, from the molecular, to the whole organ level, the determinants of cardiac excitability and arrhythmias. Along with our collaborators, our scientific investigations employ multidisciplinary approaches that include molecular and cellular biology, cellular and whole organ electrophysiology, and structural biology of ion channels, in order to investigate the mechanisms and therapeutics of cardiac pathoelectrophysiology. Our areas of scientific interest include:
- 1- The mechanisms of arrhythmogenesis in pathological conditions associated with intracellular Ca overload.
- 2- The role of the intrinsic cardiac nervous system in the generation of abnormal heart rhythm.
- 3- The role of the inward rectifier potassium channels in atrial and ventricular tachyarrhythmias.
Congratulations to Mr. John Lockhart!
We would like to congratulate Mr. John Lockhart, who has been awarded with the 2019 Keystone Symposia Scholarship and has also been invited to give a short talk about his submitted abstract entitled, “Effective Delivery of Therapeutic mRNA using Peptide-Based Nanoparticles.” This work was done in collaboration with the laboratories of Dr. Hua Pan and Dr. Samuel Wickline using a novel-based peptide nanoparticle system for oligonucleotide delivery. Mr. Lockhart is a Ph.D. candidate being mentored, by Dr. Hana Totary-Jain, who is an Assistant Professor in the Department of Molecular Pharmacology & Physiology. The Keystone Symposia will take place on April 7 – 10, 2019 in Steamboat Springs, Colorado. We are very proud of Mr. Lockhart’s accomplishments - Congratulations!