USF Heart Institute

Congratulations to Mr. John Lockhart!

We would like to congratulate Mr. John Lockhart, who has been awarded with the 2019 Keystone Symposia Scholarship and has also been invited to give a short talk about his submitted abstract entitled, “Effective Delivery of Therapeutic mRNA using Peptide-Based Nanoparticles.” This work was done in collaboration with the laboratories of Dr. Hua Pan and Dr. Samuel Wickline using a novel-based peptide nanoparticle system for oligonucleotide delivery. Mr. Lockhart is a Ph.D. candidate being mentored, by Dr. Hana Totary-Jain, who is an Assistant Professor in the Department of Molecular Pharmacology & Physiology. The Keystone Symposia will take place on April 7 – 10, 2019 in Steamboat Springs, Colorado. We are very proud of Mr. Lockhart’s accomplishments - Congratulations!


Dr. Bibhu Mohanty - Tips on Heart Health
Surface TAS2R14-WT expression with DPD treatment in HEK293T cells

Articles

A Genome-Wide Association Study of Idiopathic Dilated Cardiomyopathy in African Americans

Plot of the odds of developing idiopathic dilated cardiomyopathy (a form of heart failure) from various genetic variations on chromosome 2. A variation in a calcium channel subunit (CACNB4) showed the greatest risk for developing the disease. The population is African-American, and the results are from a recent study published from the Heart Institute.

Modulation of LIN28B/Let-7 Signaling by Propranolol Contributes to Infantile Hemangioma Involution

Infantile hemangiomas (IHs) are the most common benign vascular neoplasms of infancy, characterized by a rapid growth phase followed by a spontaneous involution, or triggered by propranolol treatment by poorly understood mechanisms. LIN28/let-7 axis plays a central role in the regulation of stem cell self-renewal and tumorigenesis. However, the role of LIN28B/let-7 signaling in IH pathogenesis has not yet been elucidated.

USF Health Institute News

12/4/2019
New USF Health research on endothelial-derived microvesicles, using models of sepsis, may be useful for better diagnosis and treatment of inflammatory or infectious diseases A new preclinical study by the University of South Florida Health (USF Health) Morsani College of Medicine sheds light on how … [read more]
11/26/2019
USF Health’s pathobiology expert Sarah Y. Yuan, PhD, is among nine USF researchers, and 450 from across the country, named new fellows of the American Association for the Advancement of Science (AAAS). The honor, announced Nov. 26, is one of the most prestigious among academic researchers worldwide. … [read more]
11/15/2019
//www.youtube.com/watch?v=xAWQcqqrnIs USF Health has established a Neurocardiogenetics Clinic focused on improving the quality of life for patients with hereditary neuromuscular disorders who are at risk for or already experiencing cardiac complications. Innovative genetic research is a central com … [read more]
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