Neurosurgery & Brain Repair

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Center of Excellence for Aging & Brain Repair

* (Neurosurgery CEABR Profile)

Cesario Borlongan

Cesario Borlongan, MA, PHD

Director, Center of Excellence for Aging & Brain Repair

Contact Info

Education

  • PHD, Psychology, Keio University, 1994

Interdisciplinary and Emerging Signature Programs

  • Allergy, Immunology & Infectious Disease
  • Biomedical Engineering & Nanomedicine
  • Cellular and Molecular Biology
  • Metabolic Regulation and Disorders
  • Neurodegenerative Disease
  • Neuroscience

Research Interests

  • CESAR V. BORLONGAN, Ph.D. is a world leader in stem cell therapy for stroke. His translational bench to clinic research has led to 6 FDA-approved clinical trials of cell transplantation, including the world's first cell therapy in stroke patients. He served as an NIH Staff Fellow for 5 years, joined the academe in 2002, and obtained Tenured Professorship in the Department of Neurology at the Medical College of Georgia, with continuous federal funding from VA, DoD, and NIH. He is an author of 500 peer-reviewed publications, lead editor of 2 books, and serves as editor of solid scientific journals, including Stem Cells, Stroke, JCBFM, Translational Stroke Research, FASEB J, Scientific Reports, Brain Research, and PLoS One. He is a regular study section member of NIH, VA, DOD,and AHA, chairs the State of Maryland Stem Cell Research Funds. He is AAAS and AIMBE Fellow, previous President of ASNTR, and current President of IPLASS. He was featured in The Lancet Neurology “Lifeline” 2008.

Awards/Honors

  • Everfront Award (Pan Pacific Symposium on Stem Cells and Cancer Research - 2017)
  • Award for Outstanding Global Research (USF - 2017)
  • Oustanding Supervisor Award (USF - 2017)
  • Donald D. Matson Lecture (AANS/CNS - 2016)

Memberships

  • Member (Society for Neuroscience, 2017 - Present)
  • Fellow (American Institute for Medical and Biological Engineering, 2017 - Present)
  • President Elect (International Placenta Stem Cell Society, 2015 - Present)
  • Fellow (Association for Psychological Science, 2015 - Present)
  • Past President (American Society for Neural Therapy and Repair, 2015 - Present)
  • Fellow (American Association for the Advancement of Science, 2015 - Present)

Recent Publications

  • Xu K Lee JY Kaneko Y Tuazon JP Vale F van Loveren H Borlongan CV. Human stem cells transplanted into the rat stroke brain migrate to the spleen via lymphatic and inflammation pathways. Haematologica. 104(5) : 1062-1073, 2019.
  • Lee JY Acosta S Tuazon JP Xu K Nguyen H Lippert T Liska MG Semechkin A Garitaonandia I Gonzalez R Kern R Borlongan CV. Human parthenogenetic neural stem cell grafts promote multiple regenerative processes in a traumatic brain injury model. Theranostics. 9(4) : 1029-1046, 2019.
  • Borlongan CV. Concise Review: Stem Cell Therapy for Stroke Patients: Are We There Yet? Stem Cells Translational Medicine. : 2019 May 16. doi: 10.1002/sctm.19-0076. [Epub ahead of print], 2019.
  • Nguyen H, Lee JY, Sanberg PR, Napoli E, Borlongan CV. Eye Opener in Stroke: Mitochondrial Dysfunction and Stem Cell Repair in Retinal Ischemia Stroke. 50(8) : 2197-2206, 2019.
  • Shinozuka K, Tajiri N, Ishikawa H, Tuazon JP, Lee JY, Sanberg PR, Zarriello S, Corey S, Kaneko Y, Borlongan CV. Empathy in stroke rats is modulated by social settings. Journal of Cerebral Blood Flow and Metabolism. : Aug 1:271678X19867908. doi: 10.1177/0271678X19867908., 2019.
  • Borlongan CV. Fatty acid chemical mediator provides insights into the pathology and treatment of Parkinson''s disease Proc Natl Acad Sci U S A.. 115(25) : 6322-6324, 2018.
  • Uchida H, Niizuma K, Kushida Y, Wakao S, Tominaga T, Borlongan CV, Dezawa M. Human Muse Cells Reconstruct Neuronal Circuitry in Subacute Lacunar Stroke Model. Stroke. 48(2) : 428-435, 2017.
  • Stonesifer C, Corey S, Ghanekar S, Diamandis Z, Acosta SA, Borlongan CV. Stem cell therapy for abrogating stroke-induced neuroinflammation and relevant secondary cell death mechanisms. Progress in neurobiology. 158: 94-131, 2017.
  • Li H, Wu J, Shen H, Yao X, Liu C, Pianta S, Han J, Borlongan CV, Chen G. Autophagy in hemorrhagic stroke: Mechanisms and clinical implications. Progress in neurobiology. , 2017.
  • Napoli E, Borlongan CV. Cell Therapy in Parkinson''s Disease: Host Brain Repair Machinery Gets a Boost From Stem Cell Grafts. Stem cells (Dayton, Ohio). 35(6) : 1443-1445, 2017.
  • Acosta SA, Tajiri N, Sanberg PR, Kaneko Y, Borlongan CV. Increased Amyloid Precursor Protein and Tau Expression Manifests as Key Secondary Cell Death in Chronic Traumatic Brain Injury. Journal of cellular physiology. 232(3) : 665-677, 2017.
  • Tajiri N, Quach DM, Kaneko Y, Wu S, Lee D, Lam T, Hayama KL, Hazel TG, Johe K, Wu MC, Borlongan CV. NSI-189, a Small Molecule with Neurogenic Properties, Exerts Behavioral and Neurostructural Benefits in Stroke Rats. Journal of cellular physiology. , 2017.
  • Tajiri N, De La Peña I, Acosta SA, Kaneko Y, Tamir S, Landesman Y, Carlson R, Shacham S, Borlongan CV. A Nuclear Attack on Traumatic Brain Injury: Sequestration of Cell Death in the Nucleus. CNS Neuroscience & Therapeutics. 22(4) : 306-15, 2016.
  • Tajiri N, Borlongan CV, Kaneko Y. Cyclosporine A Treatment Abrogates Ischemia-Induced Neuronal Cell Death by Preserving Mitochondrial Integrity through Upregulation of the Parkinson''s Disease-Associated Protein DJ-1. CNS Neuroscience & Therapeutics. 22(7) : 602-10, 2016.
  • Napoli E, Borlongan CV. Recent Advances in Stem Cell-Based Therapeutics for Stroke. Translational stroke research. , 2016.
  • Borlongan CV. Age of PISCES: stem-cell clinical trials in stroke. Lancet (London, England). 388(10046) : 736-8, 2016.
  • Toyoshima A, Yasuhara T, Kameda M, Morimoto J, Takeuchi H, Wang F, Sasaki T, Sasada S, Shinko A, Wakamori T, Okazaki M, Kondo A, Agari T, Borlongan CV, Date I. Intra-Arterial Transplantation of Allogeneic Mesenchymal Stem Cells Mounts Neuroprotective Effects in a Transient Ischemic Stroke Model in Rats: Analyses of Therapeutic Time Window and Its Mechanisms. PloS One. 10(6) : e0127302, 2015.
  • Garbuzova-Davis S, Haller E, Tajiri N, Thomson A, Barretta J, Williams SN, Haim ED, Qin H, Frisina-Deyo A, Abraham JV, Sanberg PR, Van Loveren H, Borlongan CV. Blood-Spinal Cord Barrier Alterations in Subacute and Chronic Stages of a Rat Model of Focal Cerebral Ischemia. Journal of Neuropathology and experimental neurology. 75(7) : 673-88, 2016.
  • Liska MG, Crowley MG, Nguyen H, Borlongan CV. Implication of biobridge concept in stem cell therapy for ischemic stroke. Journal of Neurosurgical sciences. , 2016.
  • Sullivan R, Duncan K, Dailey T, Kaneko Y, Tajiri N, Borlongan CV. A possible new focus for stroke treatment - migrating stem cells. Expert Opinion on Biological Therapy. 15(7) : 949-58, 2015.
  • Sullivan R, Dailey T, Duncan K, Abel N, Borlongan CV. Peripheral Nerve Injury: Stem Cell Therapy and Peripheral Nerve Transfer. International journal of molecular sciences. 17(12) , 2016.
  • Ohi Y, Kato D, Mizuno M, Sato T, Ueki Y, Borlongan CV, Ojika K, Haji A, Matsukawa N. Enhancement of long-term potentiation via muscarinic modulation in the hippocampus of HCNP precursor transgenic mice. Neuroscience Letters. 597: 1-6, 2015.
  • Kaelber S, Pantcheva P, Borlongan CV. Drug- and cell-based therapies for targeting neuroinflammation in traumatic brain injury. Neural regeneration research. 11(10) : 1575-1576, 2016.
  • Watson N, Ji X, Yasuhara T, Date I, Kaneko Y, Tajiri N, Borlongan CV. No pain, no gain: lack of exercise obstructs neurogenesis. Cell Transplantation. 24(4) : 591-7, 2015.
  • Diamandis T, Borlongan CV. One, two, three steps toward cell therapy for stroke. Stroke; A journal of cerebral circulation. 46(2) : 588-91, 2015.
  • Mashkouri S, Crowley MG, Liska MG, Corey S, Borlongan CV. Utilizing pharmacotherapy and mesenchymal stem cell therapy to reduce inflammation following traumatic brain injury. Neural regeneration research. 11(9) : 1379-1384, 2016.
  • Kikuchi Y Yasuhara T Agari T Kondo A Kuramoto S Kameda M Kadota T Baba T Tajiri N Wang F Tayra JT Liang H Miyoshi Y Borlongan CV Date I. Urinary 8-OHdG elevations in a partial lesion rat model of Parkinson''s disease correlate with behavioral symptoms and nigrostriatal dopaminergic depletion. J Cell Physiol. 226(5) : 1390-8, 2011.
  • Rodrigues MC, Lippert T, Nguyen H, Kaelber S, Sanberg PR, Borlongan CV. Menstrual Blood-Derived Stem Cells: In Vitro and In Vivo Characterization of Functional Effects. Advances in experimental medicine and biology. 951: 111-121, 2016.
  • Duncan K, Gonzales-Portillo GS, Acosta SA, Kaneko Y, Borlongan CV, Tajiri N. Stem cell-paved biobridges facilitate stem transplant and host brain cell interactions for stroke therapy. Brain Research. 1623: 160-5, 2015.
  • Borlongan CV Glover LE Tajiri N Kaneko Y Freeman TB. The great migration of bone marrow-derived stem cells toward the ischemic brain: therapeutic implications for stroke and other neurological disorders. Prog Neurobiol.. 95(2) : 213-28, 2011.
  • Borlongan CV. Preliminary Reports of Stereotaxic Stem Cell Transplants in Chronic Stroke Patients. Molecular therapy : the journal of the American Society of Gene Therapy. 24(10) : 1710-1711, 2016.
  • Reyes S, Tajiri N, Borlongan CV. Developments in intracerebral stem cell grafts. Expert Review of Neurotherapeutics. 15(4) : 381-93, 2015.
  • Kaneko Y, Pappas C, Tajiri N, Borlongan CV. Oxytocin modulates GABAAR subunits to confer neuroprotection in stroke in vitro. Scientific reports. 6: 35659, 2016.
  • Sanberg PR, Borlongan CV. Announcing a New Open Access Journal: Cell Medicine, Part B of Cell Transplantation. Cell medicine. 1(1) : 1-2, 2010.
  • Lozano D, Gonzales-Portillo GS, Acosta S, de la Pena I, Tajiri N, Kaneko Y, Borlongan CV. Neuroinflammatory responses to traumatic brain injury: etiology, clinical consequences, and therapeutic opportunities. Neuropsychiatric Disease and Treatment. 11: 97-106, 2015.
  • Kaneko Y, Eve DJ, Yu S, Shojo H, Bae EC, Park DH, Roschek B, Alberte RS, Sanberg PR, Sanberg CD, Bickford PC, Borlongan CV. Acute Treatment With Herbal Extracts Provides Neuroprotective Benefits in In Vitro and In Vivo Stroke Models, Characterized by Reduced Ischemic Cell Death and Maintenance of Motor and Neurological Functions. Cell Medicine. 1(3) : 137-142, 2010.
  • Yu G, Borlongan CV, Ou Y, Stahl CE, Yu S, Bae E, Kaneko Y, Yang T, Yuan C, Fang L. In vitro non-viral lipofectamine delivery of the gene for glial cell line-derived neurotrophic factor to human umbilical cord blood CD34+ cells. Brain Research. 1325: 147-54, 2010.
  • De La Peña I, Sanberg PR, Acosta S, Lin SZ, Borlongan CV. G-CSF as an adjunctive therapy with umbilical cord blood cell transplantation for traumatic brain injury. Cell Transplantation. 24(3) : 447-57, 2015.
  • Kaneko Y, Sullivan R, Dailey T, Vale FL, Tajiri N, Borlongan CV. Kainic Acid-Induced Golgi Complex Fragmentation/Dispersal Shifts the Proteolysis of Reelin in Primary Rat Neuronal Cells: An In Vitro Model of Early Stage Epilepsy. Molecular Neurobiology. 53(3) : 1874-83, 2016.
  • Sagisaka T, Matsukawa N, Toyoda T, Uematsu N, Kanamori T, Wake H, Borlongan CV, Ojika K. Directed neural lineage differentiation of adult hippocampal progenitor cells via modulation of hippocampal cholinergic neurostimulating peptide precursor expression. Brain Research. 1327: 107-17, 2010.
  • Sanberg PR, Borlongan CV. Announcing a new open access Journal Cell Medicine: Cell Transplantation Part B. Cell Transplantation. 19(1) : 1-2, 2010.
  • Uchida H, Morita T, Niizuma K, Kushida Y, Kuroda Y, Wakao S, Sakata H, Matsuzaka Y, Mushiake H, Tominaga T, Borlongan CV, Dezawa M. Transplantation of Unique Subpopulation of Fibroblasts, Muse Cells, Ameliorates Experimental Stroke Possibly via Robust Neuronal Differentiation. Stem Cells (Dayton, Ohio). 34(1) : 160-73, 2016.
  • Borlongan CV. Remyelinating the transected peripheral nerve by fabricated Schwann cells derived from bone marrow. Experimental Neurology. 225(2) : 243-5, 2010.
  • Lozano D Gonzales-Portillo GS Acosta S de la Pena I Tajiri N Kaneko Y Borlongan CV. Neuroinflammatory responses to traumatic brain injury: etiology, clinical consequences, and therapeutic opportunities. Neuropsychiatr Dis Treat. 11: 97-106, 2015.
  • Watson N, Diamandis T, Gonzales-Portillo C, Reyes S, Borlongan CV. Melatonin as an Antioxidant for Stroke Neuroprotection. Cell Transplantation. 25(5) : 883-91, 2016.
  • Borlongan CV, Jolkkonen J, Detante O. The future of stem cell therapy for stroke rehabilitation. Future Neurology. 10(4) : 313-319, 2015.
  • Sanberg PR, Divers R, Mehindru A, Mehindru A, Borlongan CV. Delayed Umbilical Cord Blood Clamping: First Line of Defense Against Neonatal and Age-Related Disorders. Wulfenia. 21(6) : 243-249, 2014.
  • Sasaki T, Liu K, Agari T, Yasuhara T, Morimoto J, Okazaki M, Takeuchi H, Toyoshima A, Sasada S, Shinko A, Kondo A, Kameda M, Miyazaki I, Asanuma M, Borlongan CV, Nishibori M, Date I. Anti-high mobility group box 1 antibody exerts neuroprotection in a rat model of Parkinson''s disease. Experimental Neurology. 275(1) : 220-31, 2016.
  • Masuda T, Maki M, Hara K, Yasuhara T, Matsukawa N, Yu S, Bae EC, Tajiri N, Chheda SH, Solomita MA, Weinbren N, Kaneko Y, Kirov SA, Hess DC, Hida H, Borlongan CV. Peri-hemorrhagic degeneration accompanies stereotaxic collagenase-mediated cortical hemorrhage in mouse. Brain Research. 1355: 228-39, 2010.
  • Sanberg PR, Borlongan CV. The proliferation and differentiation of stem cell journals. Stem Cell Reviews. 6(4) : 497-9, 2010.
  • Cerecedo-López CD, Kim-Lee JH, Hernandez D, Acosta SA, Borlongan CV. Insulin-associated neuroinflammatory pathways as therapeutic targets for traumatic brain injury. Medical Hypotheses. 82(2) : 171-4, 2014.
  • Eve DJ, Fillmore R, Borlongan CV, Sanberg PR. Stem cells have the potential to rejuvenate regenerative medicine research. Medical Science Monitor : International medical journal of experimental and clinical research. 16(10) : RA197-217, 2010.
  • Gonzales-Portillo C, Ishikawa H, Shinozuka K, Tajiri N, Kaneko Y, Borlongan CV. Stroke and cardiac cell death: Two peas in a pod. Clinical Neurology and Neurosurgery. 142: 145-7, 2016.
  • Tajiri N, Duncan K, Borlongan MC, Pabon M, Acosta S, de la Pena I, Hernadez-Ontiveros D, Lozano D, Aguirre D, Reyes S, Sanberg PR, Eve DJ, Borlongan CV, Kaneko Y. Adult stem cell transplantation: is gender a factor in stemness? International Journal of Molecular Sciences. 15(9) : 15225-43, 2014.
  • Ou Y, Yu S, Kaneko Y, Tajiri N, Bae EC, Chheda SH, Stahl CE, Yang T, Fang L, Hu K, Borlongan CV, Yu G. Intravenous infusion of GDNF gene-modified human umbilical cord blood CD34+ cells protects against cerebral ischemic injury in spontaneously hypertensive rats. Brain Research. 1366: 217-25, 2010.
  • Shojo H, Kaneko Y, Mabuchi T, Kibayashi K, Adachi N, Borlongan CV. Genetic and histologic evidence implicates role of inflammation in traumatic brain injury-induced apoptosis in the rat cerebral cortex following moderate fluid percussion injury. Neuroscience. 171(4) : 1273-82, 2010.
  • Tajiri N, Lee JY, Acosta S, Sanberg PR, Borlongan CV. Breaking the blood brain barrier to aid stem cell therapeutics in the chronic stroke brain. Cell Transplantation. , 2016.
  • Tajiri N, Acosta S, Portillo-Gonzales GS, Aguirre D, Reyes S, Lozano D, Pabon M, Dela Peña I, Ji X, Yasuhara T, Date I, Solomita MA, Antonucci I, Stuppia L, Kaneko Y, Borlongan CV. Therapeutic outcomes of transplantation of amniotic fluid-derived stem cells in experimental ischemic stroke. Frontiers in Cellular Neuroscience. 8: 227, 2014.
  • Hsueh KW, Chiou TW, Chiang SF, Yamashita T, Abe K, Borlongan CV, Sanberg PR, Huang AY, Lin SZ, Harn HJ. Autophagic down-regulation in motor neurons remarkably prolongs the survival of ALS mice. Neuropharmacology. 108: 152-60, 2016.
  • Gonzales-Portillo GS, Reyes S, Aguirre D, Pabon MM, Borlongan CV. Stem cell therapy for neonatal hypoxic-ischemic encephalopathy. Frontiers in Neurology. 5: 147, 2014.
  • Antonucci I, Provenzano M, Rodrigues M, Pantalone A, Salini V, Ballerini P, Borlongan CV, Stuppia L. Amniotic Fluid Stem Cells: A Novel Source for Modeling of Human Genetic Diseases. International Journal of Molecular Sciences. 17(4) , 2016.
  • de la Peña I, Sanberg PR, Acosta S, Lin SZ, Borlongan CV. Umbilical cord blood cell and granulocyte-colony stimulating factor: combination therapy for traumatic brain injury. Regenerative Medicine. 9(4) : 409-12, 2014.
  • Smith AJ, Kim SH, Tan J, Sneed KB, Sanberg PR, Borlongan CV, Shytle RD. Plasma and Brain Pharmacokinetics of Previously Unexplored Lithium Salts. RSC Advances. 4(24) : 12362-12365, 2014.
  • Shinko A, Agari T, Kameda M, Yasuhara T, Kondo A, Tayra JT, Sato K, Sasaki T, Sasada S, Takeuchi H, Wakamori T, Borlongan CV, Date I. Spinal cord stimulation exerts neuroprotective effects against experimental Parkinson''s disease. PloS One. 9(7) : e101468, 2014.
  • Tajiri N, Duncan K, Antoine A, Pabon M, Acosta SA, de la Pena I, Hernadez-Ontiveros DG, Shinozuka K, Ishikawa H, Kaneko Y, Yankee E, McGrogan M, Case C, Borlongan CV. Stem cell-paved biobridge facilitates neural repair in traumatic brain injury. Frontiers in Systems Neuroscience. 8: 116, 2014.
  • Nguyen H, Aum D, Mashkouri S, Rao G, Vega Gonzales-Portillo JD, Reyes S, Borlongan CV. Growth factor therapy sequesters inflammation in affording neuroprotection in cerebrovascular diseases. Expert Review of Neurotherapeutics. 16(8) : 915-26, 2016.
  • Pabón MM, Acosta S, Guedes VA, Tajiri N, Kaneko Y, Borlongan CV. Brain Region-Specific Histopathological Effects of Varying Trajectories of Controlled Cortical Impact Injury Model of Traumatic Brain Injury. CNS Neuroscience & Therapeutics. 22(3) : 200-11, 2016.
  • Acosta SA, Tajiri N, de la Pena I, Bastawrous M, Sanberg PR, Kaneko Y, Borlongan CV. Alpha-synuclein as a pathological link between chronic traumatic brain injury and Parkinson''s disease. Journal of Cellular Physiology. 230(5) : 1024-32, 2015.
  • Acosta SA, Tajiri N, Hoover J, Kaneko Y, Borlongan CV. Intravenous Bone Marrow Stem Cell Grafts Preferentially Migrate to Spleen and Abrogate Chronic Inflammation in Stroke. Stroke; A journal of cerebral circulation. 46(9) : 2616-27, 2015.
  • Eve DJ, Fillmore RW, Borlongan CV, Sanberg PR. Stem cell research in cell transplantation: sources, geopolitical influence, and transplantation. Cell Transplantation. 19(11) : 1493-509, 2010.
  • de la Pena I, Pabon M, Acosta S, Sanberg PR, Tajiri N, Kaneko Y, Borlongan CV. Oligodendrocytes engineered with migratory proteins as effective graft source for cell transplantation in multiple sclerosis. Cell Medicine. 6(3) : 123-127, 2014.
  • Pabon M, Tamboli C, Tamboli S, Acosta S, De La Pena I, Sanberg PR, Tajiri N, Kaneko Y, Borlongan CV. ESTROGEN REPLACEMENT THERAPY FOR STROKE. Cell Medicine. 6(3) : 111-122, 2014.
  • Zhang Y, Ying G, Ren C, Jizhang Y, Brogan D, Liu Z, Li S, Ding Y, Borlongan CV, Zhang J, Ji X. Administration of human platelet-rich plasma reduces infarction volume and improves motor function in adult rats with focal ischemic stroke. Brain Research. 1594: 267-73, 2015.
  • Tajiri N, Staples M, Kaneko Y, Kim SU, Zesiewicz TA, Borlongan CV. Autologous stem cell transplant with gene therapy for Friedreich ataxia. Medical Hypotheses. 83(3) : 296-8, 2014.
  • Emerich DF Silva E Ali O Mooney D Bell W Yu SJ Kaneko Y Borlongan CV. Injectable VEGF hydrogels produce near complete neurological and anatomical protection following cerebral ischemia in rats. Cell Transplant. , 2010.
  • Dela Peña I, Sanberg PR, Acosta S, Tajiri N, Lin SZ, Borlongan CV. Stem cells and G-CSF for treating neuroinflammation in traumatic brain injury: aging as a comorbidity factor. Journal of Neurosurgical sciences. 58(3) : 145-9, 2014.
  • Watson N, Divers R, Kedar R, Mehindru A, Mehindru A, Borlongan MC, Borlongan CV. Discarded Wharton jelly of the human umbilical cord: a viable source for mesenchymal stromal cells. Cytotherapy. 17(1) : 18-24, 2015.
  • Bachstetter AD Jernberg J Schlunk A Vila JL Hudson C Cole MJ Shytle RD Tan J Sanberg PR Sanberg CD Borlongan CV Kaneko Y Tajiri N Gemma C Bickford PC. Spirulina promotes stem cell genesis and protects against LPS induced declines in neural stem cell proliferation. PLoS One.. 5(5) : e10496, 2010.
  • dela Peña IC, Yoo A, Tajiri N, Acosta SA, Ji X, Kaneko Y, Borlongan CV. Granulocyte colony-stimulating factor attenuates delayed tPA-induced hemorrhagic transformation in ischemic stroke rats by enhancing angiogenesis and vasculogenesis. Journal of Cerebral Blood Flow and Metabolism : Official journal of the International Society of Cerebral Blood Flow and Metabolism. 35(2) : 338-46, 2015.
  • Tajiri N, Quach DM, Kaneko Y, Wu S, Lee D, Lam T, Hayama KL, Hazel TG, Johe K, Wu MC, Borlongan CV. Behavioral and histopathological assessment of adult ischemic rat brains after intracerebral transplantation of NSI-566RSC cell lines. PloS One. 9(3) : e91408, 2014.
  • Parolini O Alviano F Bergwerf I Boraschi D De Bari C De Waele P Dominici M Evangelista M Falk W Hennerbichler S Hess DC Lanzoni G Liu B Marongiu F McGuckin C Mohr S Nolli ML Ofir R Ponsaerts P Romagnoli L Solomon A Soncini M Strom S Surbek D Venkatachalam S Wolbank S Zeisberger S Zeitlin A Zisch A Borlongan CV. Toward cell therapy using placenta-derived cells: disease mechanisms, cell biology, preclinical studies, and regulatory aspects at the round table. Stem Cells Dev.. 19(2) : 143-54, 2010.
  • Garbuzova-Davis S, Haller E, Williams SN, Haim ED, Tajiri N, Hernandez-Ontiveros DG, Frisina-Deyo A, Boffeli SM, Sanberg PR, Borlongan CV. Compromised blood-brain barrier competence in remote brain areas in ischemic stroke rats at the chronic stage. The Journal of Comparative neurology. 522(13) : 3120-37, 2014.
  • Pabón MM, Ji XM, Fernandez JW, Borlongan CV. Gender-linked stem cell alterations in stroke and postpartum depression. CNS Neuroscience & Therapeutics. 21(4) : 348-56, 2015.
  • Tajiri N, Hernandez D, Acosta S, Shinozuka K, Ishikawa H, Ehrhart J, Diamandis T, Gonzales-Portillo C, Borlongan MC, Tan J, Kaneko Y, Borlongan CV. Suppressed cytokine expression immediatey following traumatic brain injury in neonatal rats indicates an expeditious endogenous anti-inflammatory response. Brain Research. 1559: 65-71, 2014.
  • Kaneko Y, Tajiri N, Staples M, Reyes S, Lozano D, Sanberg PR, Freeman TB, van Loveren H, Kim SU, Borlongan CV. Bone marrow-derived stem cell therapy for metastatic brain cancers. Cell Transplantation. 24(4) : 625-30, 2015.
  • Lin D, De La Pena I, Lin L, Zhou SF, Borlongan CV, Cao C. The neuroprotective role of acupuncture and activation of the BDNF signaling pathway. International Journal of Molecular Sciences. 15(2) : 3234-52, 2014.
  • Gonzales-Portillo GS, Sanberg PR, Franzblau M, Gonzales-Portillo C, Diamandis T, Staples M, Sanberg CD, Borlongan CV. Mannitol-enhanced delivery of stem cells and their growth factors across the blood-brain barrier. Cell Transplantation. 23(4) : 531-9, 2014.
  • Tolosa JN, Park DH, Eve DJ, Klasko SK, Borlongan CV, Sanberg PR. Mankind''s first natural stem cell transplant. Journal of Cellular and Molecular Medicine. 14(3) : 488-95, 2010.
  • Antonucci I, Di Pietro R, Alfonsi M, Centurione MA, Centurione L, Sancilio S, Pelagatti F, D''Amico MA, Di Baldassarre A, Piattelli A, Tetè S, Palka G, Borlongan CV, Stuppia L. Human second trimester amniotic fluid cells are able to create embryoid body-like structures in vitro and to show typical expression profiles of embryonic and primordial germ cells. Cell Transplantation. 23(12) : 1501-15, 2014.
  • Li S, Ma C, Shao G, Esmail F, Hua Y, Jia L, Qin J, Ren C, Luo Y, Ding Y, Borlongan CV, Ji X. Safety and Feasibility of Remote Limb Ischemic Preconditioning in Patients With Unilateral Middle Cerebral Artery Stenosis and Healthy Volunteers. Cell Transplantation. 24(9) : 1901-11, 2015.
  • Borlongan CV Parolini O. International Placenta Stem Cell Society: Planting the Seed for Placenta Stem Cell Research. Cell Transplant. , 2009.
  • Sawmiller D, Li S, Shahaduzzaman M, Smith AJ, Obregon D, Giunta B, Borlongan CV, Sanberg PR, Tan J. Luteolin reduces Alzheimer''s disease pathologies induced by traumatic brain injury. International Journal of Molecular Sciences. 15(1) : 895-904, 2014.
  • Tajiri N, Acosta SA, Shahaduzzaman M, Ishikawa H, Shinozuka K, Pabon M, Hernandez-Ontiveros D, Kim DW, Metcalf C, Staples M, Dailey T, Vasconcellos J, Franyuti G, Gould L, Patel N, Cooper D, Kaneko Y, Borlongan CV, Bickford PC. Intravenous transplants of human adipose-derived stem cell protect the brain from traumatic brain injury-induced neurodegeneration and motor and cognitive impairments: cell graft biodistribution and soluble factors in young and aged rats. The Journal of Neuroscience : the official journal of the Society for Neuroscience. 34(1) : 313-26, 2014.
  • Jacotte-Simancas A, Costa-Miserachs D, Coll-Andreu M, Torras-Garcia M, Borlongan CV, Portell-Cortés I. Effects of voluntary physical exercise, citicoline, and combined treatment on object recognition memory, neurogenesis, and neuroprotection after traumatic brain injury in rats. Journal of Neurotrauma. 32(10) : 739-51, 2015.
  • Mimura O Ishikawa H Kimura N Kimura A Borlongan CV. Retrospective study of recession of four horizontal rectus muscle in periodic alternating nystagmus. Clin Ophthalmol. 8: 2523-8, 2014.
  • Gonzales-Portillo GS, Lozano D, Aguirre D, Reyes S, Borlongan CV, Tajiri N, Kaneko Y. An update on the use of melatonin as a stroke therapeutic. Minerva Medica. 106(3) : 169-75, 2015.
  • Savitz SI Cramer SC Wechsler L; STEPS 3 Consortium. Stem cells as an emerging paradigm in stroke 3: enhancing the development of clinical trials. Stroke.. 45(2) : 634-9, 2014.
  • Lawton C, Acosta S, Watson N, Gonzales-Portillo C, Diamandis T, Tajiri N, Kaneko Y, Sanberg PR, Borlongan CV. Enhancing endogenous stem cells in the newborn via delayed umbilical cord clamping. Neural Regeneration Research. 10(9) : 1359-62, 2015.
  • Poulos SG, Richie WD, Bailey RK, Lee A, Dela Peña I, Sanberg PR, Borlongan CV. The potential of neural stem cell transplantation for the treatment of fetal alcohol spectrum disorder. Progress in Neuro-Pychopharmacology & Biological Psychiatry. 54: 149-56, 2014.
  • Elias M, Hoover J, Nguyen H, Reyes S, Lawton C, Borlongan CV. Stroke therapy: the potential of amniotic fluid-derived stem cells. Future Neurology. 10(4) : 321-326, 2015.
  • Acosta SA, Tajiri N, Shinozuka K, Ishikawa H, Sanberg PR, Sanchez-Ramos J, Song S, Kaneko Y, Borlongan CV. Combination therapy of human umbilical cord blood cells and granulocyte colony stimulating factor reduces histopathological and motor impairments in an experimental model of chronic traumatic brain injury. PloS One. 9(3) : e90953, 2014.
  • Pantcheva P, Reyes S, Hoover J, Kaelber S, Borlongan CV. Treating non-motor symptoms of Parkinson''s disease with transplantation of stem cells. Expert Review of Neurotherapeutics. 15(10) : 1231-40, 2015.
  • Kaneko Y, Shojo H, Burns J, Staples M, Tajiri N, Borlongan CV. DJ-1 ameliorates ischemic cell death in vitro possibly via mitochondrial pathway. Neurobiology of Disease. 62: 56-61, 2014.
  • Pantcheva P, Elias M, Duncan K, Borlongan CV, Tajiri N, Kaneko Y. The role of DJ-1 in the oxidative stress cell death cascade after stroke. Neural Regeneration Research. 9(15) : 1430-3, 2014.
  • Borlongan CV, Burns J, Tajiri N, Stahl CE, Weinbren NL, Shojo H, Sanberg PR, Emerich DF, Kaneko Y, van Loveren HR. Epidemiological survey-based formulae to approximate incidence and prevalence of neurological disorders in the United States: a meta-analysis. PloS One. 8(10) : e78490, 2013.
  • Ishikawa H, Akura J, Uchida K, Ikeda N, Ikeda T, Borlongan CV, Mimura O. A case with transient refractive change after removal of pituitary tumor. BMC Ophthalmology. 13: 65, 2013.
  • Sato K, Kameda M, Yasuhara T, Agari T, Baba T, Wang F, Shinko A, Wakamori T, Toyoshima A, Takeuchi H, Sasaki T, Sasada S, Kondo A, Borlongan CV, Matsumae M, Date I. Neuroprotective effects of liraglutide for stroke model of rats. International Journal of Molecular Sciences. 14(11) : 21513-24, 2013.
  • Dailey T, Mosley Y, Pabon M, Acosta S, Tajiri N, van Loveren H, Kaneko Y, Borlongan CV. Advancing critical care medicine with stem cell therapy and hypothermia for cerebral palsy. Neuroreport. 24(18) : 1067-71, 2013.
  • Shinozuka K, Dailey T, Tajiri N, Ishikawa H, Kaneko Y, Borlongan CV. Stem cell transplantation for neuroprotection in stroke. Brain Sciences. 3(1) : 239-61, 2013.
  • Yu S, Tajiri N, Franzese N, Franzblau M, Bae E, Platt S, Kaneko Y, Borlongan CV. Stem cell-like dog placenta cells afford neuroprotection against ischemic stroke model via heat shock protein upregulation. PloS One. 8(9) : e76329, 2013.
  • Shinozuka K, Dailey T, Tajiri N, Ishikawa H, Kim DW, Pabon M, Acosta S, Kaneko Y, Borlongan CV. Stem Cells for Neurovascular Repair in Stroke. Journal of Stem Cell Research & therapy. 4(4) : 12912, 2013.
  • Franzblau M, Gonzales-Portillo C, Gonzales-Portillo GS, Diamandis T, Borlongan MC, Tajiri N, Borlongan CV. Vascular damage: a persisting pathology common to Alzheimer''s disease and traumatic brain injury. Medical Hypotheses. 81(5) : 842-5, 2013.
  • Diamandis T, Gonzales-Portillo C, Gonzales-Portillo GS, Staples M, Borlongan MC, Hernandez D, Acosta S, Borlongan CV. Diabetes insipidus contributes to traumatic brain injury pathology via CD36 neuroinflammation. Medical Hypotheses. 81(5) : 936-9, 2013.
  • Staples M, Acosta S, Tajiri N, Pabon M, Kaneko Y, Borlongan CV. Delta opioid receptor and its peptide: a receptor-ligand neuroprotection. International Journal of Molecular Sciences. 14(9) : 17410-9, 2013.
  • Shahaduzzaman M, Acosta S, Bickford PC, Borlongan CV. α-Synuclein is a pathological link and therapeutic target for Parkinson''s disease and traumatic brain injury. Medical Hypotheses. 81(4) : 675-80, 2013.
  • Dailey T, Tajiri N, Kaneko Y, Borlongan CV. Regeneration of neuronal cells following cerebral injury. Frontiers of Neurology and Neuroscience. 32: 54-61, 2013.
  • Kim DW, Staples M, Shinozuka K, Pantcheva P, Kang SD, Borlongan CV. Wharton''s jelly-derived mesenchymal stem cells: phenotypic characterization and optimizing their therapeutic potential for clinical applications. International Journal of Molecular Sciences. 14(6) : 11692-712, 2013.
  • Shinozuka K, Staples M, Borlongan CV. Melatonin-based therapeutics for neuroprotection in stroke. International Journal of Molecular Sciences. 14(5) : 8924-47, 2013.
  • Tajiri N, Dailey T, Metcalf C, Mosley YI, Lau T, Staples M, van Loveren H, Kim SU, Yamashima T, Yasuhara T, Date I, Kaneko Y, Borlongan CV. In vivo animal stroke models: a rationale for rodent and non-human primate models. Translational Stroke Research. 4(3) : 308-21, 2013.
  • Garbuzova-Davis S, Rodrigues MC, Hernandez-Ontiveros DG, Tajiri N, Frisina-Deyo A, Boffeli SM, Abraham JV, Pabon M, Wagner A, Ishikawa H, Shinozuka K, Haller E, Sanberg PR, Kaneko Y, Borlongan CV. Blood-brain barrier alterations provide evidence of subacute diaschisis in an ischemic stroke rat model. PloS One. 8(5) : e63553, 2013.
  • Pabon MM, Borlongan CV. ADVANCES IN THE CELL-BASED TREATMENT OF NEONATAL HYPOXIC-ISCHEMIC BRAIN INJURY. Future Neurology. 8(2) : 193-203, 2013.
  • Hernandez-Ontiveros DG, Tajiri N, Acosta S, Giunta B, Tan J, Borlongan CV. Microglia activation as a biomarker for traumatic brain injury. Frontiers in Neurology. 4: 30, 2013.
  • Kaneko Y, Pabon MM, Dailey T, Weinbren NL, Rizzi J, Tamboli C, Vasconcellos J, Kuzmin-Nichols N, Sanberg PR, Eve DJ, Tajiri N, Borlongan CV. The battle of the sexes for stroke therapy: female- versus male-derived stem cells. CNS & Neurological Disorders drug targets. 12(3) : 405-12, 2013.
  • Ishikawa H, Caputo M, Franzese N, Weinbren NL, Slakter A, Patel M, Stahl CE, Jacotte MA, Acosta S, Franyuti G, Shinozuka K, Tajiri N, van Loveren H, Kaneko Y, Borlongan CV. Stroke in the eye of the beholder. Medical Hypotheses. 80(4) : 411-5, 2013.
  • Dailey T Metcalf C Mosley YI Sullivan R Shinozuka K Tajiri N Pabon M Acosta S Kaneko Y van Loveren H Borlongan CV. An Update on Translating Stem Cell Therapy for Stroke from Bench to Bedside. J Clin Med.. 2(4) : 220-241, 2013.
  • Hong SH Lee HJ An J Lim I Borlongan C Aboody KS Kim SU. Human neural stem cells expressing carboxyl esterase target and inhibit tumor growth of lung cancer brain metastases. Cancer Gene Ther.. 20(12) : 678-82, 2013.
  • Shinozuka K Staples M Borlongan CV. Melatonin-based therapeutics for neuroprotection in stroke. Int J Mol Sci.. 14(5) : 8924-47, 2013.
  • Liu R Zhang Z Lu Z Borlongan CV Pan J Chen J Qian L Liu Z Zhu L Zhang J Xu Y. Human Umbilical Cord Stem Cells Ameliorate Experimental Autoimmune Encephalomyelitis by Regulating Immunoinflammation and Remyelination. Stem Cells Dev. , 2013.
  • Acosta SA, Tajiri N, Shinozuka K, Ishikawa H, Grimmig B, Diamond DM, Diamond D, Sanberg PR, Bickford PC, Kaneko Y, Borlongan CV. Long-term upregulation of inflammation and suppression of cell proliferation in the brain of adult rats exposed to traumatic brain injury using the controlled cortical impact model. PloS One. 8(1) : e53376, 2013.
  • Tajiri N, Kellogg SL, Shimizu T, Arendash GW, Borlongan CV. Traumatic brain injury precipitates cognitive impairment and extracellular Aβ aggregation in Alzheimer''s disease transgenic mice. PloS One. 8(11) : e78851, 2013.
  • Ishikawa H, Tajiri N, Shinozuka K, Vasconcellos J, Kaneko Y, Lee HJ, Mimura O, Dezawa M, Kim SU, Borlongan CV. Vasculogenesis in experimental stroke after human cerebral endothelial cell transplantation. Stroke; a journal of cerebral circulation. 44(12) : 3473-81, 2013.
  • Tajiri N, Kaneko Y, Shinozuka K, Ishikawa H, Yankee E, McGrogan M, Case C, Borlongan CV. Stem cell recruitment of newly formed host cells via a successful seduction? Filling the gap between neurogenic niche and injured brain site. PloS One. 8(9) : e74857, 2013.
  • Ishikawa H, Tajiri N, Vasconcellos J, Kaneko Y, Mimura O, Dezawa M, Borlongan CV. Ischemic stroke brain sends indirect cell death signals to the heart. Stroke; a journal of cerebral circulation. 44(11) : 3175-82, 2013.
  • Takahashi Y, Yasuhara T, Kumamoto S, Yoneda K, Tanoue T, Nakahara M, Inoue T, Hijikata Y, Lee T, Borlongan CV, Ogawa K, Nishida K. Laterality of cervical disc herniation. European Spine Journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 22(1) : 178-82, 2013.
  • Acosta SA, Diamond DM, Wolfe S, Tajiri N, Shinozuka K, Ishikawa H, Hernandez DG, Sanberg PR, Kaneko Y, Borlongan CV. Influence of post-traumatic stress disorder on neuroinflammation and cell proliferation in a rat model of traumatic brain injury. PloS One. 8(12) : e81585, 2013.
  • Acosta SA, Franzese N, Staples M, Weinbren NL, Babilonia M, Patel J, Merchant N, Simancas AJ, Slakter A, Caputo M, Patel M, Franyuti G, Franzblau MH, Suarez L, Gonzales-Portillo C, Diamandis T, Shinozuka K, Tajiri N, Sanberg PR, Kaneko Y, Miller LW, Borlongan CV. Human Umbilical Cord Blood for Transplantation Therapy in Myocardial Infarction. Journal of Stem Cell Research & Therapy. (4) : supplement, 2013.
  • Yasuhara T, Agari T, Kameda M, Kondo A, Kuramoto S, Jing M, Sasaki T, Toyoshima A, Sasada S, Sato K, Shinko A, Wakamori T, Okuma Y, Miyoshi Y, Tajiri N, Borlongan CV, Date I. Regenerative medicine for epilepsy: from basic research to clinical application. International Journal of Molecular Sciences. 14(12) : 23390-401, 2013.
  • Kaneko Y, Tajiri N, Yu S, Hayashi T, Stahl CE, Bae E, Mestre H, Franzese N, Rodrigues A, Rodrigues MC, Ishikawa H, Shinozuka K, Hethorn W, Weinbren N, Glover LE, Tan J, Achyuta AH, van Loveren H, Sanberg PR, Shivsankar S, Borlongan CV. Nestin overexpression precedes caspase-3 upregulation in rats exposed to controlled cortical impact traumatic brain injury. Cell Medicine. 4(2) : 55-63, 2012.
  • Rodrigues MC, Hernandez-Ontiveros DG, Louis MK, Willing AE, Borlongan CV, Sanberg PR, Voltarelli JC, Garbuzova-Davis S. Neurovascular aspects of amyotrophic lateral sclerosis. International Review of Neurobiology. 102: 91-106, 2012.
  • Borlongan CV, Glover LE, Sanberg PR, Hess DC. Permeating the blood brain barrier and abrogating the inflammation in stroke: implications for stroke therapy. Current Pharmaceutical Design. 18(25) : 3670-6, 2012.
  • Glover LE, Tajiri N, Lau T, Kaneko Y, van Loveren H, Borlongan CV. Immediate, but not delayed, microsurgical skull reconstruction exacerbates brain damage in experimental traumatic brain injury model. PloS One. 7(3) : e33646, 2012.
  • Tajiri N, Lau T, Glover LE, Shinozuka K, Kaneko Y, van Loveren H, Borlongan CV. Cerebral aneurysm as an exacerbating factor in stroke pathology and a therapeutic target for neuroprotection. Current Pharmaceutical Design. 18(25) : 3663-9, 2012.
  • Borlongan CV, Rodrigues AA, Oliveira MC. Breaking the barrier in stroke: what should we know? A mini-review. Current Pharmaceutical Design. 18(25) : 3615-23, 2012.
  • Glover LE, Tajiri N, Weinbren NL, Ishikawa H, Shinozuka K, Kaneko Y, Watterson DM, Borlongan CV. A Step-up Approach for Cell Therapy in Stroke: Translational Hurdles of Bone Marrow-Derived Stem Cells. Translational Stroke Research. 3(1) : 90-8, 2012.
  • Toyoda T, Matsukawa N, Sagisaka T, Uematsu N, Kanamori T, Kato D, Mizuno M, Wake H, Hida H, Borlongan CV, Ojika K. Suppression of astrocyte lineage in adult hippocampal progenitor cells expressing hippocampal cholinergic neurostimulating Peptide precursor in an in vivo ischemic model. Cell Transplantation. 21(10) : 2159-69, 2012.
  • Rodrigues MC, Voltarelli J, Sanberg PR, Allickson JG, Kuzmin-Nichols N, Garbuzova-Davis S, Borlongan CV. Recent progress in cell therapy for basal ganglia disorders with emphasis on menstrual blood transplantation in stroke. Neuroscience and Biobehavioral Reviews. 36(1) : 177-90, 2012.
  • Sanberg PR, Eve DJ, Cruz LE, Borlongan CV. Neurological disorders and the potential role for stem cells as a therapy. British Medical Bulletin. 101: 163-81, 2012.
  • Antonucci I, Pantalone A, Tete S, Salini V, Borlongan CV, Hess D, Stuppia L. Amniotic fluid stem cells: a promising therapeutic resource for cell-based regenerative therapy. Current Pharmaceutical Design. 18(13) : 1846-63, 2012.
  • Arendash GW Mori T Dorsey M Gonzalez R Tajiri N Borlongan CV. Electromagnetic treatment to old Alzheimer''s mice reverses β-amyloid deposition, modifies cerebral blood flow, and provides selected cognitive benefit. PLoS One. 7(4) : e35751, 2012.
  • Borlongan CV. The blood brain barrier in stroke. Current Pharmaceutical Design. 18(25) : 3613-4, 2012.
  • Tajiri N, Acosta S, Glover LE, Bickford PC, Jacotte Simancas A, Yasuhara T, Date I, Solomita MA, Antonucci I, Stuppia L, Kaneko Y, Borlongan CV. Intravenous grafts of amniotic fluid-derived stem cells induce endogenous cell proliferation and attenuate behavioral deficits in ischemic stroke rats. PloS One. 7(8) : e43779, 2012.
  • Giunta B, Obregon D, Velisetty R, Sanberg PR, Borlongan CV, Tan J. The immunology of traumatic brain injury: a prime target for Alzheimer''s disease prevention. Journal of Neuroinflammation. 9: 185, 2012.
  • Kaneko Y, Cortes L, Sanberg C, Acosta S, Bickford PC, Borlongan CV. Dietary supplementations as neuroprotective therapies: focus on NT-020 diet benefits in a rat model of stroke. International Journal of Molecular Sciences. 13(6) : 7424-44, 2012.
  • Borlongan CV. Recent preclinical evidence advancing cell therapy for Alzheimer''s disease. Experimental Neurology. 237(1) : 142-6, 2012.
  • Garbuzova-Davis S, Hernandez-Ontiveros DG, Rodrigues MC, Haller E, Frisina-Deyo A, Mirtyl S, Sallot S, Saporta S, Borlongan CV, Sanberg PR. Impaired blood-brain/spinal cord barrier in ALS patients. Brain Research. 1469: 114-28, 2012.
  • Kaneko Y, Tajiri N, Shinozuka K, Glover LE, Weinbren NL, Cortes L, Borlongan CV. Cell therapy for stroke: emphasis on optimizing safety and efficacy profile of endothelial progenitor cells. Current Pharmaceutical Design. 18(25) : 3731-4, 2012.
  • Rodrigues MC, Dmitriev D, Rodrigues A, Glover LE, Sanberg PR, Allickson JG, Kuzmin-Nichols N, Tajiri N, Shinozuka K, Garbuzova-Davis S, Kaneko Y, Borlongan CV. Menstrual blood transplantation for ischemic stroke: Therapeutic mechanisms and practical issues. Interventional Medicine & Applied Science. 4(2) : 59-68, 2012.
  • Rodrigues MC, Rodrigues AA, Glover LE, Voltarelli J, Borlongan CV. Peripheral nerve repair with cultured schwann cells: getting closer to the clinics. The Scientific World Journal. 2012: 413091, 2012.
  • Kaneko Y, Tajiri N, Su TP, Wang Y, Borlongan CV. Combination treatment of hypothermia and mesenchymal stromal cells amplifies neuroprotection in primary rat neurons exposed to hypoxic-ischemic-like injury in vitro: role of the opioid system. PloS One. 7(10) : e47583, 2012.
  • Sanberg PR, Eve DJ, Metcalf C, Borlongan CV. Advantages and challenges of alternative sources of adult-derived stem cells for brain repair in stroke. Progress in Brain Research. 201: 99-117, 2012.
  • Kaneko Y, Hayashi T, Yu S, Tajiri N, Bae EC, Solomita MA, Chheda SH, Weinbren NL, Parolini O, Borlongan CV. Human amniotic epithelial cells express melatonin receptor MT1, but not melatonin receptor MT2: a new perspective to neuroprotection. Journal of Pineal Research. 50(3) : 272-80, 2011.
  • Lulic D, Burns J, Bae EC, van Loveren H, Borlongan CV. A review of laboratory and clinical data supporting the safety and efficacy of cyclosporin A in traumatic brain injury. Neurosurgery. 68(5) : 1172-85; discussion 1185-6, 2011.
  • Manuelpillai, U.|Moodley, Y.|Borlongan, C.V.|Parolini, O. Amniotic membrane and amniotic cells: Potential therapeutic tools to combat tissue inflammation and fibrosis? Placenta. 32: S320-5, 2011.
  • Parolini O, Alviano F, Betz AG, Bianchi DW, Götherström C, Manuelpillai U, Mellor AL, Ofir R, Ponsaerts P, Scherjon SA, Weiss ML, Wolbank S, Wood KJ, Borlongan CV. Meeting report of the first conference of the International Placenta Stem Cell Society (IPLASS). Placenta. 32 Suppl 4: S285-90, 2011.
  • Osman MM, Lulic D, Glover L, Stahl CE, Lau T, van Loveren H, Borlongan CV. Cyclosporine-A as a neuroprotective agent against stroke: its translation from laboratory research to clinical application. Neuropeptides. 45(6) : 359-68, 2011.
  • Garbuzova-Davis S, Rodrigues MC, Hernandez-Ontiveros DG, Louis MK, Willing AE, Borlongan CV, Sanberg PR. Amyotrophic lateral sclerosis: a neurovascular disease. Brain Research. 1398: 113-25, 2011.
  • Borlongan CV, Weiss MD. Baby STEPS: a giant leap for cell therapy in neonatal brain injury. Pediatric Research. 70(1) : 3-9, 2011.
  • Allickson JG, Sanchez A, Yefimenko N, Borlongan CV, Sanberg PR. Recent Studies Assessing the Proliferative Capability of a Novel Adult Stem Cell Identified in Menstrual Blood. The Open Stem Cell Journal. 3(2011) : 4-10, 2011.
  • Eve DJ, Borlongan CV, Sanberg PR. A showcase of bench-to-bedside regenerative medicine at the 2010 ASNTR. The Scientific World Journal. 11: 1842-64, 2011.
  • Rodrigues MC, Glover LE, Weinbren N, Rizzi JA, Ishikawa H, Shinozuka K, Tajiri N, Kaneko Y, Sanberg PR, Allickson JG, Kuzmin-Nichols N, Garbuzova-Davis S, Voltarelli JC, Cruz E, Borlongan CV. Toward personalized cell therapies: autologous menstrual blood cells for stroke. Journal of Biomedicine & Biotechnology. 2011: 194720, 2011.
  • Park DH, Lee JH, Borlongan CV, Sanberg PR, Chung YG, Cho TH. Transplantation of umbilical cord blood stem cells for treating spinal cord injury. Stem Cell Reviews. 7(1) : 181-94, 2011.
  • Sanberg PR, Eve DJ, Willing AE, Garbuzova-Davis S, Tan J, Sanberg CD, Allickson JG, Cruz LE, Borlongan CV. The treatment of neurodegenerative disorders using umbilical cord blood and menstrual blood-derived stem cells. Cell Transplantation. 20(1) : 85-94, 2011.
  • Antonucci I, Stuppia L, Kaneko Y, Yu S, Tajiri N, Bae EC, Chheda SH, Weinbren NL, Borlongan CV. Amniotic fluid as a rich source of mesenchymal stromal cells for transplantation therapy. Cell Transplantation. 20(6) : 789-95, 2011.
  • Morimoto T, Yasuhara T, Kameda M, Baba T, Kuramoto S, Kondo A, Takahashi K, Tajiri N, Wang F, Meng J, Ji YW, Kadota T, Maruo T, Kinugasa K, Miyoshi Y, Shingo T, Borlongan CV, Date I. Striatal stimulation nurtures endogenous neurogenesis and angiogenesis in chronic-phase ischemic stroke rats. Cell Transplantation. 20(7) : 1049-64, 2011.
  • Borlongan CV. Bone marrow stem cell mobilization in stroke: a ''bonehead'' may be good after all! Leukemia. 25(11) : 1674-86, 2011.
  • Borlongan CV, Glover LE, Tajiri N, Kaneko Y, Freeman TB. The great migration of bone marrow-derived stem cells toward the ischemic brain: therapeutic implications for stroke and other neurological disorders. Progress in Neurobiology. 95(2) : 213-28, 2011.
  • Emerich DF Orive G Borlongan CV. Tales of Biomaterials, Molecules, and Cells for Repairing and Treating Brain Dysfunction. Curr Stem Cell Res Ther.. , 2011.