1. Molecular mechanisms underlying learning-dependent modulation of ingestive behavior. Main goal of this project is to understand the complete mechanisms of the molecular events (e.g. networks of genes) in the brain (e.g. networks of neurons) that underlie hedonic coding, which will make it possible to pharmacologically increase the palatability of less caloric dense foods (e.g. low sugar/low fat).
2. NIH/NIA R03 AG064338-01A1: “Hyperoxia exposure in an aging model of Type-1 diabetes”. 05/15/2020 – 03/31/2022.
3. NIH/NIA R15 AG064674-01A1: “Hyperoxia-induced Kv channel regulation in an aging mouse model”. 05/01/2020 – 04/30/2023.
4. USF COVID-19 Rapid Response Research Proposal
IRESCV2 #100255: "Detrimental effects of hyperoxia on Covid-19 infected mice model" 05/28/2020 – 05/27/2021.
Awards/Honors
Fellow of Association of Biotechnology and Pharmacy (ABAP - 2009)
Memberships
Professional Member (AHA, 2011 - Present)
Member (SFN, 2009 - Present)
Member (AChems, 2009 - Present)
Recent Publications
Panguluri SK, Tur J, Fukumoto J, Deng W, Sneed KB, Kolliputi N, Bennett ES, Tipparaju SM. Hyperoxia-induced hypertrophy and ion channel remodeling in left ventricle.American journal of physiology. Heart and circulatory physiology. 304(12) : H1651-61, 2013.
Panguluri SK, Tur J, Chapalamadugu KC, Katnik C, Cuevas J, Tipparaju SM. MicroRNA-301a mediated regulation of Kv4.2 in diabetes: identification of key modulators.PloS one. 8(4) : e60545, 2013.
Panguluri SK, Kuwabara N, Kang Y, Cooper N, Lundy RF. Conditioned taste aversion dependent regulation of amygdala gene expression.Physiology & behavior. 105(4) : 996-1006, 2012.
Panguluri SK, Kakar SS. Using quantitative real-time reverse transcriptase polymerase chain reaction to validate gene regulation by PTTG.Methods in molecular biology (Clifton, N.J.). 815: 131-45, 2012.
Bhatnagar S, Panguluri SK, Kumar A. Gene profiling studies in skeletal muscle by quantitative real-time polymerase chain reaction assay.Methods in molecular biology (Clifton, N.J.). 798: 311-24, 2012.
Kumar S, Kumar A, Shah PP, Rai SN, Panguluri SK, Kakar SS. MicroRNA signature of cis-platin resistant vs. cis-platin sensitive ovarian cancer cell lines.Journal of ovarian research. 4(1) : 17, 2011.
Paul PK, Gupta SK, Bhatnagar S, Panguluri SK, Darnay BG, Choi Y, Kumar A. Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice.The Journal of cell biology. 191(7) : 1395-411, 2010.
Pathan FK, Venkata DA, Panguluri SK. Recent patents on antimicrobial peptides.Recent patents on DNA & gene sequences. 4(1) : 10-6, 2010.
Panguluri SK, Bhatnagar S, Kumar A, McCarthy JJ, Srivastava AK, Cooper NG, Lundy RF, Kumar A. Genomic profiling of messenger RNAs and microRNAs reveals potential mechanisms of TWEAK-induced skeletal muscle wasting in mice.PloS one. 5(1) : e8760, 2010.
Panguluri SK, Kakar SS. Effect of PTTG on endogenous gene expression in HEK 293 cells.BMC genomics. 10: 577, 2009.
Panguluri SK, Yeakel C, Kakar SS. PTTG: an important target gene for ovarian cancer therapy.Journal of ovarian research. 1(1) : 6, 2008.
Panguluri SK, Li B, Hormann RE, Palli SR. Effect of ecdysone receptor gene switch ligands on endogenous gene expression in 293 cells.The FEBS journal. 274(21) : 5669-89, 2007.
Panguluri SK, Kumar P, Palli SR. Functional characterization of ecdysone receptor gene switches in mammalian cells.The FEBS journal. 273(24) : 5550-63, 2006.
Panguluri SK, Sridhar J, Jagadish B, Sharma PC, Kumar PA. Isolation and characterization of a green tissue-specific promoter from pigeonpea [Cajanus cajan (L.) Millsp.].Indian journal of experimental biology. 43(4) : 369-72, 2005.
Bhalla R, Dalal M, Panguluri SK, Jagadish B, Mandaokar AD, Singh AK, Kumar PA. Isolation, characterization and expression of a novel vegetative insecticidal protein gene of Bacillus thuringiensis.FEMS microbiology letters. 243(2) : 467-72, 2005.