Dae Hyun Lee, MD

Assistant Professor, Department of Internal Medicine; Division of Cardiovascular Sciences

Contact Info

• Academic Email: daehyunlee@usf.edu

Biography

Dr. Dae Hyun Lee is a cardio-oncology and cardiology specialist in Tampa, Florida. He graduated from Inha University School of Medicine in 2012. He completed his Internal Medicine and Cardiovascular Disease Fellowship at the University of South Florida in 2023. He is board-certified in cardiovascular disease, cardio-oncology, comprehensive echocardiography, and nuclear cardiology. His core values include being a compassionate cardiologist whose most important priority is the well-being of his patients. He specializes in cardio-oncology, a subspecialty focusing on cardiovascular care in patients with cancer. He communicates closely with oncology doctors to plan for the best cardiovascular care for patients with cancer.

Research Interests

• Dr. Lee is an experienced researcher in cardiovascular medicine. His research focus is on cardio-oncology to prevent and treat harmful effects of cancer (from cancer, chemotherapy, radiation therapy, etc.) in the cardiovascular system. He has published over 40 peer-reviewed articles in numerous prestigious journals, including the Journal of American College of Cardiology (JACC), Blood Advances, Heart, and the Journal of Heart and Lung Transplant (JHLT). He recently received funding from “Casey DeSantis Florida Cancer Innovation Fund” from the Florida Department of Health.

Recent Publications

• Lee DH, Usmani A, Ravichandran V, Wicks T, Wu R, Wolf-Doty T, Dumitru I, Berman P, Oliveira GH, Mackie B. Relationship between blood and tissue-based rejection-related transcripts in heart transplantation J Heart Lung Transplant. 43(3) : 359-368, 2024.
• Scoma CB, Lee DH, Money D, Eichelberger G, Usmani A, Cohen AJ, Fernandez J The Impact of Midodrine On Guideline-Directed Medical Therapy in Patients Admitted with Systolic Heart Failure J Cardiovasc Pharmacol. , 2023.
• Lee DH, Eichelberger GS, Patel V, Chhaya R, Khadilkar A, Bishop J, Bezerra H, Oliveira G, Matar F, Fernandez J Referral for Cardiac Amyloidosis in Patients Who Underwent Transcatheter Aortic Valve Replacement: Results of the Quality Outcome Project Cureus. 15(9) : e45024, 2023.
• Lee DH, Kumar A, Mohammed T, Peres LC, Alsina M, Bachmeier C, Blue BJ, Brayer J, Chandrasekhar S, Grajales Cruz A, De Avila G, Elmariah H, Faramand R, Freeman C, Jain M, Khadka S, Khimani F, Liu H, Nishihori T, Oswald LB, Castaneda Puglianini OA, Sha Cardiac events after standard of care idecabtagene vicleucel for relapsed and refractory multiple myeloma Blood Adv. 7(16) : 4247-4257, 2023.
• Lee DH, Chandrasekhar S, Jain MD, Mhaskar R, Reid K, Lee SB, Corallo S, Hidalgo-Vargas MJ, Kumar A, Chavez J, Shah B, Lazaryan A, Khimani F, Nishihori T, Bachmeier C, Faramand R, Fradley MG, Jeong D, Oliveira GH, Locke FL, Davila ML, Alomar M Cardiac and inflammatory biomarker differences in adverse cardiac events after chimeric antigen receptor T-Cell therapy: an exploratory study Cardiooncology. 9(1) : 18, 2023.
• Lee DH, Jain M, Lazaryan A, Locke FL, Jeong D, Alomar M Case of Myocarditis After Chimeric Antigen Receptor T Cells With Intracardiac Lymphoma JACC Case Rep. 8: 101634, 2023.
• Money DB, Lee DH, Hadar A, Doherty J, Malanga C, Serino A, Cohen AJ Amiodarone for the Treatment of Arrhythmias in COVID-19 Patients Does Not Increase the Risk of Pulmonary Fibrosis: A Retrospective Cohort Study Cureus. 15(1) : e34109, 2023.
• Halade GV, Lee DH Inflammation and resolution signaling in cardiac repair and heart failure EBioMedicine. 79: 103992, 2022.
• Lee DH, Money DB, Deshpande A, Samuels B A Case of Abiraterone-Related Hypokalemia Leading to Torsades de Pointes and Cardiac Arrest Cureus. 14(3) : e23678, 2022.
• Lee DH, Hawk F, Seok K, Gliksman M, Emole J, Rhea IB, Viganego F, Welter-Frost A, Armanious M, Shah B, Chavez JC, Pinilla-Ibarz J, Schabath MB, Fradley M Association between ibrutinib treatment and hypertension Heart. 108(6) : 445-450, 2022.
• Lee DH, Patel RH, Mehra I, Shenoy R, Nanjappa S, Greene J A Case Series of Elizabethkingia meningosepticum Bacteremia in the Cancer Population Cureus. 13(10) : e18627, 2021.
• Lee DH, Kasprowicz T, Morales A, Sotolongo I, Fernandez J, Korabathina R A Case of Infiltrative Cardiomyopathy Secondary to Primary Hyperoxaluria Type 2 - Utilization of Multimodality Imaging Cureus. 13(9) : e17914, 2021.
• Chandrasekhar S, Lee DH, Patel N, Bassily E, Chen A A Case of Rapid Development of Methicillin‑Resistant Staphylococcus aureus Mechanical Aortic Root Abscess Despite Appropriate Antibiotic Use Cureus. 13(8) : e17494, 2021.
• Lee DH, Kambhampati S, Mohammed M, Goli R, Thiemann D, Lawson B, Resar J, Mohanty B Efficacy of Coronary Computed Tomography Angiography for the De Novo Detection of Chronic Total Occlusion Prior to Coronary Angiography: A Preliminary and Retrospective Study Int J Angiol. 29(4) : 223-228, 2020.
• Lee DH, Kumar A, Radoianu N, Ehren L, Bassil C A Case of Diffuse and Nodular Glomerulosclerosis in Waldenstrom's Macroglobulinemia Cureus. 12(9) : e10694, 2020.
• Lee DH, Armanious M, Huang J, Jeong D, Druta M, Fradley MG Case of pembrolizumab-induced myocarditis presenting as torsades de pointes with safe re-challenge J Oncol Pharm Pract. 26(6) : 1544-1548, 2020.
• Pineda-Gayoso R, Alomar M, Lee DH, Fradley MG Cardiovascular Toxicities of Bruton's Tyrosine Kinase Inhibitors Curr Treat Options Oncol. 21(8) : 67, 2020.
• Fradley MG, Welter-Frost A, Gliksman M, Emole J, Viganego F, Lee DH, Shah B, Chavez JC, Pinilla-Ibarz J, Schabath MB Electrocardiographic Changes Associated With Ibrutinib Exposure Cancer Control. 27(1) : 1073274820931808, 2020.
• Alvi RM, Frigault MJ, Fradley MG, Jain MD, Mahmood SS, Awadalla M, Lee DH, Zlotoff DA, Zhang L, Drobni ZD, Hassan MZO, Bassily E, Rhea I, Ismail-Khan R, Mulligan CP, Banerji D, Lazaryan A, Shah BD, Rokicki A, Raje N, Chavez JC, Abramson J, Locke FL, Cardiovascular Events Among Adults Treated With Chimeric Antigen Receptor T-Cells (CAR-T) J Am Coll Cardiol. 74(25) : 3099-3108, 2019.
• Lee DH, Chandrashekhar S, Fradley MG Electrophysiologic Complications in Cancer Patients Methodist Debakey Cardiovasc J. 15(4) : 282-288, 2019.
• Fradley MG, Gliksman M, Emole J, Viganego F, Rhea I, Welter-Frost A, Armanious M, Lee DH, Walko C, Shah B, Chavez JC, McLeod H, Pinilla-Ibarz J, Schabath MB Rates and Risk of Atrial Arrhythmias in Patients Treated With Ibrutinib Compared With Cytotoxic Chemotherapy Am J Cardiol. 124(4) : 539-544, 2019.
• Lee DH, Klinkova O, Kim JW, Nanjappa S, Greene JN A Case Series of Staphylococcus lugdunensis Infection in Cancer Patients at an Academic Cancer Institute in the United States Infect Chemother. 51(1) : 45-53, 2019.
• Lee DH, Moon ME, Go Y, Song J, Kim J, Kim C, Seo KH, Kim S, Kim J Appropriateness of task of public health doctors in South Korea Rural Remote Health. 18(4) : 4723, 2018.
• Denham JD, Lee DH, Castro M, Pandya S, Aslam S, Nanjappa S, Greene JN Two cases of disseminated infection following live organism anti-cancer vaccine administration in cancer patients Int J Infect Dis. 72: 1-2, 2018.
• Lee DH, Fradley MG Cardiovascular Complications of Multiple Myeloma Treatment: Evaluation, Management, and Prevention Curr Treat Options Cardiovasc Med. 20(3) : 19, 2018.
• Helmerhorst HJF, de Wilde RBP, Lee DH, Palmen M, Jansen JRC, van Westerloo DJ, de Jonge E Hemodynamic effects of short-term hyperoxia after coronary artery bypass grafting Ann Intensive Care. 7(1) : 20, 2017.
• Boels MG, Avramut MC, Koudijs A, Dane MJ, Lee DH, van der Vlag J, Koster AJ, van Zonneveld AJ, van Faassen E, Gröne HJ, van den Berg BM, Rabelink TJ Atrasentan Reduces Albuminuria by Restoring the Glomerular Endothelial Glycocalyx Barrier in Diabetic Nephropathy Diabetes. 65(8) : 2429-2439, 2016.
• Han S, Lee SJ, Kim KE, Lee HS, Oh N, Park I, Ko E, Oh SJ, Lee YS, Kim D, Lee S, Lee DH, Lee KH, Chae SY, Lee JH, Kim SJ, Kim HC, Kim S, Kim SH, Kim C, Nakaoka Y, He Y, Augustin HG, Hu J, Song PH, Kim YI, Kim P, Kim I, Koh GY Amelioration of sepsis by TIE2 activation-induced vascular protection Sci Transl Med. 8(335) : 335ra55, 2016.
• de Bruin RG, van der Veer EP, Prins J, Lee DH, Dane MJ, Zhang H, Roeten MK, Bijkerk R, de Boer HC, Rabelink TJ, van Zonneveld AJ, van Gils JM The RNA-binding protein quaking maintains endothelial barrier function and affects VE-cadherin and β-catenin protein expression Sci Rep. 6: 21643, 2016.
• Dane MJ, van den Berg BM, Lee DH, Boels MG, Tiemeier GL, Avramut MC, van Zonneveld AJ, van der Vlag J, Vink H, Rabelink TJ A microscopic view on the renal endothelial glycocalyx Am J Physiol Renal Physiol. 308(9) : F956-966, 2015.
• Kwon HN, Lee YJ, Kang JH, Choi JH, An YJ, Kang S, Lee DH, Suh YJ, Heo Y, Park S Prediction of glycated hemoglobin levels at 3 months after metabolic surgery based on the 7-day plasma metabolic profile PLoS One. 9(11) : e109609, 2014.
• Lee DH, Dane MJ, van den Berg BM, Boels MG, van Teeffelen JW, de Mutsert R, den Heijer M, Rosendaal FR, van der Vlag J, van Zonneveld AJ, Vink H, Rabelink TJ Deeper penetration of erythrocytes into the endothelial glycocalyx is associated with impaired microvascular perfusion PLoS One. 9(5) : e96477, 2014.
• Dane MJ, Khairoun M, Lee DH, van den Berg BM, Eskens BJ, Boels MG, van Teeffelen JW, Rops AL, van der Vlag J, van Zonneveld AJ, Reinders ME, Vink H, Rabelink TJ Association of kidney function with changes in the endothelial surface layer Clin J Am Soc Nephrol. 9(4) : 698-704, 2014.
• Boels MG, Lee DH, van den Berg BM, Dane MJ, van der Vlag J, Rabelink TJ The endothelial glycocalyx as a potential modifier of the hemolytic uremic syndrome Eur J Intern Med. 24(6) : 503-509, 2013.
• Wen H, Yang HJ, An YJ, Kim JM, Lee DH, Jin X, Park SW, Min KJ, Park S Enhanced phase II detoxification contributes to beneficial effects of dietary restriction as revealed by multi-platform metabolomics studies Mol Cell Proteomics. 12(3) : 575-586, 2013.
• Kang HK, Yoon MH, Lee DH, Chin HS Pharmacogenetic influence of LOC387715/HTRA1 on the efficacy of bevacizumab treatment for age-related macular degeneration in a Korean population Korean J Ophthalmol. 26(6) : 414-422, 2012.