Advanced techniques such as X-ray crystallography and cryo-electron microscopy to elucidate the 3D structures of biological macromolecules.

Crystallography

Crystallization screening, crystal optimization, data collection strategy, phasing, refinement, and deposition.

Cryo-EM

Sample vitrification support, grid screening, data-collection coordination, image processing and model building.

Biophysics

Binding and stability assays (as available), ligand validation, and integration with computation/chemistry.