Burt Anderson, Ph.D.

Infectious Disease Researcher

Associate Professor, Department of Medical Microbiology and Immunology

Assistant Professor, Department of Medical Microbiology and Immunology

Supervisory Research Microbiologist, Viral and Rickettsial Zoonoses Branch

Adjunct Assistant Professor, Dept. of Biology

Microbiologist, Staphylococcus and Streptococcus Unit and Sexually Transmitted Diseases Lab Program

Contact Info 12901 Bruce B. Downs Blvd
MDC7
Tampa FL 33612

Academic Email: banderso@usf.edu

Academic Phone:(813) 974-2608

View My C.V.

Education

Interdisciplinary and Emerging Signature Programs

• Allergy, Immunology & Infectious Disease

Research Interests

• The primary focus of our laboratory is how facultative intracellular bacteria control expression of genes required for virulence. We currently study how Bartonella henselae regulates expression of genes required to mediate the unique vascular proliferation that is observed in patients infected with this bacterium. More recently we have focused on the role of sRNAs in gene regulatory circuits required for virulence in B. henselae.

Memberships

• Member (Florida Center of Excellence Center for Biomolecular Identification and Targeted Therapeutics, 2007 - Present)
• Member and Journal Club Coordinator (SIPAIID, 2005 - Present)
• President (American Society of Rickettsiology, 2001 - 2003)
• Member (H. Lee Moffitt Cancer Center and Research Institute, 1997 - Present)
• Member (American Society for Microbiology, 1986 - Present)

Recent Publications

• Okaro U, Addisu A, Casanas B, Anderson B. Bartonella Species, an Emerging Cause of Blood-Culture-Negative Endocarditis. Clinical microbiology reviews. 30(3) : 709-746, 2017.
• Tu N, Carroll RK, Weiss A, Shaw LN, Nicolas G, Thomas S, Lima A, Okaro U, Anderson B. A family of genus-specific RNAs in tandem with DNA-binding proteins control expression of the badA major virulence factor gene in Bartonella henselae. MicrobiologyOpen. , 2016.
• Tu N, Lima A, Bandeali Z, Anderson B. Characterization of the general stress response in Bartonella henselae. Microbial pathogenesis. 92: 1-10, 2016.
• Lima A, Cha BJ, Amin J, Smith LK, Anderson B. Zebrafish Embryo Model of Bartonella henselae Infection. Zebrafish. 11(5) : 434-46, 2014.
• Minnick MF, Anderson BE, Lima A, Battisti JM, Lawyer PG, Birtles RJ. Oroya fever and verruga peruana: bartonelloses unique to South America. PLoS neglected tropical diseases. 8(7) : e2919, 2014.
• Cormier R, Burda WN, Harrington L, Edlinger J, Kodigepalli KM, Thomas J, Kapolka R, Roma G, Anderson BE, Turos E, Shaw LN. Studies on the antimicrobial properties of N-acylated ciprofloxacins. Bioorganic & medicinal chemistry letters. 22(20) : 6513-20, 2012.
• Ramaraju P, Gergeres D, Turos E, Dickey S, Lim DV, Thomas J, Anderson B. Synthesis and antimicrobial activities of structurally novel S,S''-bis(heterosubstituted) disulfides. Bioorganic & medicinal chemistry letters. 22(11) : 3623-31, 2012.
• Gillaspie D, Perkins I, Larsen K, McCord A, Pangonis S, Sweger D, Seleem MN, Sriranganathan N, Anderson BE. Plasmid-based system for high-level gene expression and antisense gene knockdown in Bartonella henselae. Applied and environmental microbiology. 75(16) : 5434-6, 2009.
• Sammons-Jackson WL, McClelland K, Manch-Citron JN, Metzger DW, Bakshi CS, Garcia E, Rasley A, Anderson BE. Generation and characterization of an attenuated mutant in a response regulator gene of Francisella tularensis live vaccine strain (LVS). DNA and cell biology. 27(7) : 387-403, 2008.
• McCord AM, Cuevas J, Anderson BE. Bartonella-induced endothelial cell proliferation is mediated by release of calcium from intracellular stores. DNA and cell biology. 26(9) : 657-63, 2007.
• McCord AM, Resto-Ruiz SI, Anderson BE. Autocrine role for interleukin-8 in Bartonella henselae-induced angiogenesis. Infection and immunity. 74(9) : 5185-5190, 2006.
• Dabo SM, Confer AW, Saliki JT, Anderson BE. Binding of Bartonella henselae to extracellular molecules: identification of potential adhesins. Microbial pathogenesis. 41(1) : 10-20, 2006.
• Dabo SM, Confer AW, Anderson BE, Gupta S. Bartonella henselae Pap31, an extracellular matrix adhesin, binds the fibronectin repeat III13 module. Infection and immunity. 74(5) : 2513-21, 2006.
• McCord AM, Burgess AW, Whaley MJ, Anderson BE. Interaction of Bartonella henselae with endothelial cells promotes monocyte/macrophage chemoattractant protein 1 gene expression and protein production and triggers monocyte migration. Infection and immunity. 73(9) : 5735-5742, 2005.
• Riess T, Anderson B, Fackelmayer A, Autenrieth IB, Kempf VA. Rapid and efficient transposon mutagenesis of Bartonella henselae by transposome technology. Gene. 313: 103-109, 2003.
• Resto-Ruiz S, Burgess A, Anderson BE. The role of the host immune response in pathogenesis of Bartonella henselae. DNA and cell biology. 22(6) : 431-440, 2003.
• Resto-Ruiz SI, Schmiederer M, Sweger D, Newton C, Klein TW, Friedman H, Anderson BE. Induction of a potential paracrine angiogenic loop between human THP-1 macrophages and human microvascular endothelial cells during Bartonella henselae infection. Infection and immunity. 70(8) : 4564-4570, 2002.
• Ayoub EM, McBride J, Schmiederer M, Anderson B. Role of Bartonella henselae in the etiology of Henoch-Schönlein purpura. The Pediatric infectious disease journal. 21(1) : 28-31, 2002.
• Burgess AW, Paquet JY, Letesson JJ, Anderson BE. Isolation, sequencing and expression of Bartonella henselae omp43 and predicted membrane topology of the deduced protein. Microbial pathogenesis. 29(2) : 73-80, 2000.
• Minnick MF, Anderson BE. Bartonella interactions with host cells. Sub-cellular biochemistry. 33: 97-123, 2000.
• Wang Q, Vasey FB, Mahfood JP, Valeriano J, Kanik KS, Anderson BE, Bridgeford PH. V2 regions of 16S ribosomal RNA used as a molecular marker for the species identification of streptococci in peripheral blood and synovial fluid from patients with psoriatic arthritis. Arthritis and rheumatism. 42(10) : 2055-9, 1999.
• Burgess AW, Anderson BE. Outer membrane proteins of Bartonella henselae and their interaction with human endothelial cells. Microbial pathogenesis. 25(3) : 157-64, 1998.
• Anderson BE, Neuman MA. Bartonella spp. as emerging human pathogens. Clinical microbiology reviews. 10(2) : 203-19, 1997.
• Arraga-Alvarado C, Montero-Ojeda M, Bernardoni A, Anderson BE, Parra O. [Human ehrlichiosis: report of the 1st case in Venezuela] Investigación clínica. 37(1) : 35-49, 1996.
• McDade JE, Anderson BE. Molecular epidemiology: applications of nucleic acid amplification and sequence analysis. Epidemiologic reviews. 18(1) : 90-7, 1996.
• Holmes AH, Greenough TC, Balady GJ, Regnery RL, Anderson BE, O''Keane JC, Fonger JD, McCrone EL. Bartonella henselae endocarditis in an immunocompetent adult. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 21(4) : 1004-7, 1995.
• Demers DM, Bass JW, Vincent JM, Person DA, Noyes DK, Staege CM, Samlaska CP, Lockwood NH, Regnery RL, Anderson BE. Cat-scratch disease in Hawaii: etiology and seroepidemiology. The Journal of pediatrics. 127(1) : 23-6, 1995.
• Sumner JW, Sims KG, Jones DC, Anderson BE. Protection of guinea-pigs from experimental Rocky Mountain spotted fever by immunization with baculovirus-expressed Rickettsia rickettsii rOmpA protein. Vaccine. 13(1) : 29-35, 1995.
• Waldvogel K, Regnery RL, Anderson BE, Caduff R, Caduff J, Nadal D. Disseminated cat-scratch disease: detection of Rochalimaea henselae in affected tissue. European journal of pediatrics. 153(1) : 23-7, 1994.
• Kakoma I, Hansen RD, Anderson BE, Hanley TA, Sims KG, Liu L, Bellamy C, Long MT, Baek BK. Cultural, molecular, and immunological characterization of the etiologic agent for atypical canine ehrlichiosis. Journal of clinical microbiology. 32(1) : 170-5, 1994.
• Sumner JW, Sims KG, Jones DC, Anderson BE. Ehrlichia chaffeensis expresses an immunoreactive protein homologous to the Escherichia coli GroEL protein. Infection and immunity. 61(8) : 3536-9, 1993.
• Anderson BE, Sims KG, Olson JG, Childs JE, Piesman JF, Happ CM, Maupin GO, Johnson BJ. Amblyomma americanum: a potential vector of human ehrlichiosis. The American journal of tropical medicine and hygiene. 49(2) : 239-44, 1993.
• Anderson BE, Greene CE, Jones DC, Dawson JE. Ehrlichia ewingii sp. nov., the etiologic agent of canine granulocytic ehrlichiosis. International journal of systematic bacteriology. 42(2) : 299-302, 1992.
• Anderson BE, Sumner JW, Dawson JE, Tzianabos T, Greene CR, Olson JG, Fishbein DB, Olsen-Rasmussen M, Holloway BP, George EH. Detection of the etiologic agent of human ehrlichiosis by polymerase chain reaction. Journal of clinical microbiology. 30(4) : 775-80, 1992.
• Regnery RL, Anderson BE, Clarridge JE, Rodriguez-Barradas MC, Jones DC, Carr JH. Characterization of a novel Rochalimaea species, R. henselae sp. nov., isolated from blood of a febrile, human immunodeficiency virus-positive patient. Journal of clinical microbiology. 30(2) : 265-74, 1992.
• Anderson BE, Dawson JE, Jones DC, Wilson KH. Ehrlichia chaffeensis, a new species associated with human ehrlichiosis. Journal of clinical microbiology. 29(12) : 2838-42, 1991.
• Dawson JE, Anderson BE, Fishbein DB, Sanchez JL, Goldsmith CS, Wilson KH, Duntley CW. Isolation and characterization of an Ehrlichia sp. from a patient diagnosed with human ehrlichiosis. Journal of clinical microbiology. 29(12) : 2741-5, 1991.
• Anderson BE, McDonald GA, Jones DC, Regnery RL. A protective protein antigen of Rickettsia rickettsii has tandemly repeated, near-identical sequences. Infection and immunity. 58(9) : 2760-9, 1990.

Positions Held

• Infectious Disease Researcher (VA Medical Center 1994 - 2008)
• Associate Professor (Department of Medical Microbiology and Immunology, College of Medicine 1999 - 2004)
• Assistant Professor (Department of Medical Microbiology and Immunology, College of Medicine 1994 - 1999)
• Supervisory Research Microbiologist (Viral and Rickettsial Zoonoses Branch, Centers for Disease Control 1984 - 1994)
• Adjunct Assistant Professor (Dept. of Biology, Georgia State University 1992 - 1994)
• Microbiologist (Staphylococcus and Streptococcus Unit and Sexually Transmitted Diseases Lab Program, Centers for Disease Control 1980 - 1984)

Awards/Honors

• BACP (Bacterial Pathogenesis) Study Section (NIH - 2014)
• BACP (Bacterial Pathogenesis) Study Section (NIH - 2013)
• BACP (Bacterial Pathogenesis) Study Section (NIH - 2012)
• President's Award for Faculty Excellence (USF - 2003)