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Molecular Medicine

Molecular Medicine

Nicholas Burdash, Ph.D.

Nicholas Burdash, Ph.D.

Professor, Molecular Medicine

Professor & Chairman, Department of Microbiology & Immunology

Associate Director, Microbiology and Diagnostic Immunology

Professor, Laboratory Medicine

Associate Professor, Laboratory Medicine

Assistant Director, Diagnostic Immunology

Assistant Director, Clinical Microbiology

Chief of Research and Development, Division of Clinical Microbiology

Assistant Professor of Laboratory Medicine, Department of Laboratory Medicine

Assistant Professor, Department of Microbiology

Contact Info 12901 Bruce B. Downs Blvd.
Tampa FL 33612

Academic Email:

Academic Phone:(813) 974-7016

View My C.V.


  • PHD, Microbiology, Ohio State University, 1969

Interdisciplinary and Emerging Signature Programs

  • Allergy, Immunology & Infectious Disease

Research Interests

  • Immunological aspects of infectious disease
  • Selected articles
  • Rogers, J., Perkins, I., van Olphen, A. Burdash, N., Klein, T.W. and Friedman, H. Epigallocatechin Gallate Modulates Cytokine Production by Bone Marrow Derived Dendritic Cells Stimulated with Lipopolysaccharide or Muramylpeptide, or Infected with Legionella pneumophila, Exp Biol Med, 9:645-651, 2005.
  • Rogers, J., Perkins, I., van Olphen, A., Burdash, N., Klein, T.W., and Freidman, H. Legionella Infection of Bone Marrow Dendritic Cells Induces Modulation by Catechins. Chap 78. In Legionella: State of the Art 30 Years after its Recognition, Ed. Cianciooto, N.P., ASM Press, Washington, D.C. 2006.
  • Mamata,Y., Hakki, A., Newton, C., Burdash, N., Klein, T.W., and Friedman, H. Differential Effects of Chlamydia pneumonia infection on cytokine levels in human T lymphocyte and monocyte-derived cell cultures. Int J Med Micro, doi:10.1016/ijmm.2006.11.004, 2007
  • Rogers, J., Hakki, A., Perkins, I., Newton, C., Widen, R., Burdash, N. Klein, T., and Friedman, H. Legionella pneumphila Infection Up-regulates Dendritic Cell TLR 2/4 Expression and Key Maturation Markers. Inf & Immun 75:3205-3208, 2007
  • Rogers,J., Friedman, H., Hakki, A., Boyd, T., Perkins, I., Widen, R., Burdash, N., and Klein, TW. Major Green Tea Catechin Inhibits Cell Maturation and TLR2/TLR4 Expression Induced by Legionella pneumophila Infection, Submitted to Int J of Med Micro

Recent Publications

  • Rogers J, Hakki A, Perkins I, Newton C, Widen R, Burdash N, Klein T, Friedman H. Legionella pneumophila infection up-regulates dendritic cell Toll-like receptor 2 (TLR2)/TLR4 expression and key maturation markers. Infection and immunity. 75(6) : 3205-8, 2007.
  • Mamata Y, Hakki A, Newton C, Burdash N, Klein TW, Friedman H. Differential effects of Chlamydia pneumoniae infection on cytokine levels in human T lymphocyte- and monocyte-derived cell cultures. International journal of medical microbiology : IJMM. 297(2) : 109-15, 2007.
  • Rogers J, Perkins I, van Olphen A, Burdash N, Klein TW, Friedman H. Epigallocatechin gallate modulates cytokine production by bone marrow-derived dendritic cells stimulated with lipopolysaccharide or muramyldipeptide, or infected with Legionella pneumophila. Experimental biology and medicine (Maywood, N.J.). 230(9) : 645-51, 2005.
  • Thrush DN, Austin D, Burdash N. Cardiopulmonary bypass temperature does not affect postoperative euthyroid sick syndrome? Chest. 108(6) : 1541-5, 1995.
  • Bosek V, Janssen WE, Burdash N, Nolan J, Patel M. General anesthesia and bone marrow harvesting procedure have no effect on the concentration of CD34 stem cells in peripheral venous blood. Bone marrow transplantation. 13(4) : 498, 1994.
  • Burdash N, Fernandes JJ. Hepatitis testing update. The Journal of the American Osteopathic Association. 92(8) : 1028, 1037-8, 1992.
  • Burdash N, Fernandes JJ. Group A Streptococcus detection: office versus reference laboratory. The Journal of the American Osteopathic Association. 92(2) : 231-3, 1992.
  • Burdash N, Fernandes J. Lyme borreliosis: detecting the great imitator. The Journal of the American Osteopathic Association. 91(6) : 573-4, 577-8, 1991.
  • Mathur S, Burdash NM, Williamson HO. White cell subpopulations in autoimmune infertile men and their wives with cytotoxic sperm antibodies. Autoimmunity. 6(3) : 183-93, 1990.
  • Uri JV, Bendas CM, Burdash N. Phosphorus/phosphonic acid-containing antimicrobial antibiotics (a review). Acta microbiologica Hungarica. 35(3) : 221-57, 1988.
  • Uri JV, Burdash N, Bendas CM. The aminothiazol-oxyimino cephalosporin antibiotics with quaternary ammonium substituents at the 3-position (a review). Acta microbiologica Hungarica. 35(4) : 327-59, 1988.
  • Burdash NM, Hinds KK, Finnerty JA, Manos JP. Evaluation of the syphilis Bio-EnzaBead assay for detection of treponemal antibody. Journal of clinical microbiology. 25(5) : 808-11, 1987.
  • Clarke MC, Carr R, Burdash NM, Chen ZY, Ainsworth SK. A comparison of three anti-double stranded DNA antibody assays on sera from SLE and other diseases. Diagnostic immunology. 4(6) : 288-93, 1986.
  • Self SE, Burdash NM, Ponzio AD, Lavia MF. Lymphocyte subsets in lymph node hyperplasias and B cell neoplasms as determined by fluoresceinated antibodies and flow cytometry. Annals of the New York Academy of Sciences. 468: 195-210, 1986.
  • West TE, Cantey JR, Burdash NM, Apicella MA. Enzyme-linked immunosorbent assay for detection of immunoglobulin G and M antibodies to teichoic acid in intravascular staphylococcal disease. European journal of clinical microbiology. 4(3) : 286-90, 1985.
  • Burdash NM, Welborn AL, Teti G, Bannister ER, Manos JP. Identification of gram-negative bacilli using the Autobac IDX. Diagnostic microbiology and infectious disease. 3(1) : 59-64, 1985.
  • Katikaneni LD, La Via MF, Burdash NM. Lymphocyte phenotype changes in congenital and acquired perinatal cytomegalovirus infections. Diagnostic immunology. 3(1) : 38-42, 1985.
  • La Via MF, Hurtubise PE, Parker JW, Rubin RH, Burdash NM, Spencer-Green G, Bishop DA, Dziurzynski B. T-lymphocyte subset phenotypes: a multisite evaluation of normal subjects and patients with AIDS. Diagnostic immunology. 3(2) : 75-82, 1985.
  • Teti G, Burdash NM, Zamboni C, Fava C, Tomasello F, Mastroeni P. Evaluation of a rapid method to exclude the presence of certain enteric pathogens in stool specimens. Journal of clinical microbiology. 20(6) : 1049-52, 1984.
  • Lazarchick J, Genco PV, Hall SA, Ponzio AD, Burdash NM. Detection of platelet antibodies by flow cytometric analysis. Diagnostic immunology. 2(4) : 238-41, 1984.
  • Ponzio AD, Self SE, Runey DH, Burdash NM, La Via MF. Are lymphocyte subset determinations affected by storage conditions? Diagnostic immunology. 2(3) : 188-90, 1984.
  • West TE, Cantey JR, Apicella MA, Burdash NM. Detection of anti-teichoic acid immunoglobulin G antibodies in experimental Staphylococcus epidermidis endocarditis. Infection and immunity. 42(3) : 1020-6, 1983.
  • Burdash NM, Blackburn BB, Farrar WE. Meningococcal meningitis and complement (C6) deficiency. Journal of the South Carolina Medical Association (1975). 79(8) : 440-1, 1983.
  • West TE, Burdash NM, Boehm AM, West ME. Evaluation of a commercial counterimmunoelectrophoresis kit for detection of Staphylococcus aureus teichoic acid antibodies. Journal of clinical microbiology. 17(4) : 567-70, 1983.
  • Burdash NM, Manos JP, Bannister ER, Welborn AL. Acridine orange staining and radiometric detection of microorganisms in blood cultures. Journal of clinical microbiology. 17(3) : 463-5, 1983.
  • Burges GE, Holley HP, Burdash NM, Virella G. Immunological diagnosis of systemic candidiasis by counterimmunoelectrophoresis and quantitative immunofluorescence using purified antigens. Diagnostic immunology. 1(4) : 295-302, 1983.
  • Burdash NM, Smith KA, Welborn AL. Rapid detection of Haemophilus influenzae type b in cerebrospinal fluid by commercial coagglutination and latex agglutination kits. European journal of clinical microbiology. 1(3) : 131-3, 1982.
  • Burdash NM, West ME. Identification of Streptococcus pneumoniae by the Phadebact coagglutination test. Journal of clinical microbiology. 15(3) : 391-4, 1982.
  • Manos JP, Novy CM, Condon EV, Burdash NM. Mycobacterial disease and the acid-fast smear. Journal of the South Carolina Medical Association (1975). 78(1) : 41-3, 1982.
  • Burdash NM, West ME, Newell RT, Teti G. Group identification of streptococci. Evaluation of three rapid agglutination methods. American journal of clinical pathology. 76(6) : 819-22, 1981.
  • Burdash NM, West ME. Effect of refrigeration on inoculated Micro-ID strips. Journal of clinical microbiology. 14(3) : 350-1, 1981.
  • Burdash NM, Teti G, West ME, Bannister ER, Manos JP. Evaluation of an automated, computerized system (automicrobic system) for Enterobacteriaceae identification. Journal of clinical microbiology. 13(2) : 331-4, 1981.
  • Burdash N, Ponzio A, Papadopoulos V, Loadholt CB. Methods for immunoglobulin quantitation compared. Clinical chemistry. 27(2) : 345-7, 1981.
  • Burdash NM, Bannister ER, Manos JP, West ME. A comparison of four commercial systems for the identification of nonfermentative gram-negative bacilli. American journal of clinical pathology. 73(4) : 564-9, 1980.
  • Estes GB, Muñoz M, Burdash NM, Virella G. A quantitative immunofluorescence test for the detection of anti-Candida antibodies. Journal of immunological methods. 35(1-2) : 105-13, 1980.
  • Wilson GB, Newell RT, Burdash NM. Bovine dialyzable lymph node extracts have antigen-dependent and antigen-independent effects on human cell-mediated immunity in vitro. Cellular immunology. 47(1) : 1-18, 1979.
  • Roof BS, Weinstein R, Vujic I, Burdash NM. Immuno-heterogeneity of the calcitonins of hypercalcemia, breast and lung cancers and medullary carcinoma of thyroid. Biomedicine / [publiée pour l''A.A.I.C.I.G.]. 30(2) : 82-90, 1979.
  • Burdash NM, West ME, Bannister ER, Manos JP. An identification scheme for gram-negative nonfermentative bacilli. Health laboratory science. 15(2) : 95-103, 1978.
  • Burdash NM, Bennett CE, Glassman AB. Bacterial gram staining by conventional and strip methods. Health laboratory science. 14(4) : 282-3, 1977.
  • West M, Burdash NM, Freimuth F. Simplified silver-plating stain for flagella. Journal of clinical microbiology. 6(4) : 414-9, 1977.
  • Arnaud P, Burdash NM, Wilson GB, Fudenberg HH. Alpha-1-antitrypsin (Pi) types in Down''s syndrome. Clinical genetics. 10(4) : 239-43, 1976.
  • Burdash NM, West ME, Bannister ER, Dyar C, Duncan RC. Evaluation of a dual-staining method for acid-fast bacilli. Journal of clinical microbiology. 2(2) : 149-50, 1976.
  • Burdash NM, Manos JP, Ross D, Bannister ER. Evaluation of the acid-fast smear. Journal of clinical microbiology. 4(2) : 190-1, 1976.
  • Burdash NM, West ME, Bannister ER. Automatic gram-staining with the microstainer II. Health laboratory science. 13(1) : 20-2, 1976.
  • Wilson GB, Burdash NM, Arnaud P, Monsher MT, Fudenberg HH. Carcinoembryonic antigen and cystic fibrosis protein in blood from cystic fibrosis homozygotes and heterozygote carriers. Scandinavian journal of immunology. 5(6-7) : 829-36, 1976.
  • Burdash NM, Blake JM, Hester LL. Immunoglobulin levels and liver function tests in normal and toxemic pregnancies. American journal of obstetrics and gynecology. 116(6) : 827-30, 1973.
  • Burdash NM, Ehrlich MA, Ehrlich HG, Parisi JT. Electron microscopy of Proteus vulgaris exposed to cephalothin. Journal of bacteriology. 95(5) : 1956-60, 1968.
  • Manos JP, Botting AJ, Burdash NM, Mason MH, West ME. Evaluation of a bioassay method for serum amikacin concentrations. Annals of clinical and laboratory science. 11(5) : 411-5
  • Burdash NM, Teti G, Papadopoulos V. The Crithidia luciliae and Farr assays for the detection of systemic lupus erythematosus. Annals of clinical and laboratory science. 13(1) : 49-54
  • Burdash NM, Brunson P, Fortuna P, West M, Bannister E. Identification of clinically significant anaerobic bacteria. Annals of clinical and laboratory science. 11(1) : 19-24
  • Brown EW, Burdash NM, Manos JP, Duncan RC. MIF-like activity in non-stimulated and virus infected cell cultures. Annals of clinical and laboratory science. 8(5) : 419-24
  • Burdash NM, Ponzio AD, Loadholt CB. A quantitative immunofluorescence assay for IgM rheumatoid factor. The Journal of rheumatology. 8(5) : 837-40
  • Fu ES, Norman JG, Scharf JE, Burdash N. Effect of type of anesthesia and lower-abdominal laparotomy in mice on the cytokine response to acute stress. Regional anesthesia. 21(5) : 470-3
  • Jacobs PF, Burdash NM, Manos JP, Duncan RC. Immunologic parameters in Down''s syndrome. Annals of clinical and laboratory science. 8(1) : 17-22
  • Teti G, Burdash NM, Corey K, Fava C. Detection of group B streptococci by agglutination testing from selective broth cultures. Annals of clinical and laboratory science. 15(4) : 292-8
  • Burdash NM, Teti G, Hund P. Streptococcal antibody tests in rheumatic fever. Annals of clinical and laboratory science. 16(2) : 163-70

Positions Held

  • Professor & Chairman (Department of Microbiology & Immunology, Philadelphia College of Osteopathic Medicine 1986 - 1990)
  • Associate Director (Microbiology and Diagnostic Immunology, Medical University of South Carolina 1981 - 1986)
  • Professor (Laboratory Medicine, Medical University of South Carolina 1985 - 1986)
  • Associate Professor (Laboratory Medicine, Medical University of South Carolina 1979 - 1985)
  • Assistant Director (Diagnostic Immunology, Medical University of South Carolina 1975 - 1981)
  • Assistant Director (Clinical Microbiology, Medical University of South Carolina 1976 - 1981)
  • Chief of Research and Development (Division of Clinical Microbiology, Medical University of South Carolina 1974 - 1979)
  • Assistant Professor of Laboratory Medicine (Department of Laboratory Medicine, Medical University of South Carolina 1974 - 1979)
  • Assistant Professor (Department of Microbiology, Medical University of South Carolina 1969 - 1974)