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Laboratory Research

* (Byrd Research Faculty Directory Profile)

Xuewei Wang

Xuewei Wang, Ph.D.

Assistant Professor, Department of Molecular Medicine, Morsani College of Medicine

Contact Info

Education

  • PhD, Neurobiology, Peking University, 2016
  • BMed, Basic Medical Sciences, Peking University, 2009

Interdisciplinary and Emerging Signature Programs

  • Neuroscience

Recent Publications

  • Yang SG, Li CP, Wang XW, Huang T, Qian C, Li Q, Zhao LR, Zhou SY, Ding CY, Nie R, Saijilafu, Hong YC, Liu CM, Zhou FQ. Roles of Kdm6a and Kdm6b in Regulation of Mammalian Neural Regeneration. Advanced Science. 12, 2025.
  • Wang XW, Yang SG, Hu MW, Wang RY, Zhang C, Kosanam AR, Ochuba AJ, Jiang JJ, Luo X, Guan Y, Qian J, Liu CM, Zhou FQ. Histone methyltransferase Ezh2 coordinates mammalian axon regeneration via regulation of key regenerative pathways. Journal of Clinical Investigation. 134, 2024.
  • Zhang C, Huang Q, Ford NC, Limjunyawong N, Lin Q, Yang F, Cui X, Uniyal A, Liu J, Mahabole M, He H, Wang X, Duff I, Wang Y, Wan J, Zhu G, Raja SN, Jia H, Yang D, Dong X, Cao X, Tseng SC, He S, Guan Y. Human birth tissue products as a non-opioid medicine to inhibit post-surgical pain. eLife. 13, 2024.
  • Soucy JR, Aguzzi EA, Cho J, Gilhooley MJ, Keuthan C, Luo Z, Monavarfeshani A, Saleem MA, Wang XW, Wohlschlegel J; RReSTORe Consortium; Baranov P, Di Polo A, Fortune B, Gokoffski KK, Goldberg JL, Guido W, Kolodkin AL, Mason CA, Ou Y, Reh TA, Ross AG, Samuels BC, Welsbie D, Zack DJ, Johnson TV. Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium. Molecular Neurodegeneration. 18, 2023.
  • Yang SG, Wang XW, Qian C, Zhou FQ. Reprogramming neurons for regeneration: The fountain of youth. Progress in Neurobiology. 214, 2022.
  • Zheng Q, Xie W, Lückemeyer DD, Lay M, Wang XW, Dong X, Limjunyawong N, Ye Y, Zhou FQ, Strong JA, Zhang JM, Dong X. Synchronized cluster firing, a distinct form of sensory neuron activation, drives spontaneous pain. Neuron. 110, 2022.
  • Zhang C, Hu MW, Wang XW, Cui X, Liu J, Huang Q, Cao X, Zhou FQ, Qian J, He SQ, Guan Y. scRNA-sequencing reveals subtype-specific transcriptomic perturbations in DRG neurons of PirtEGFPf mice in neuropathic pain condition. eLife. 11, 2022.
  • Jia M, Wang X, Zhang H, Wang X, Ma H, Yang M, Li Y, Cui C. MicroRNA‐132 is involved in morphine dependence via modifying the structural plasticity of the dentate gyrus neurons in rats. Addiction Biology. 27, 2022.
  • Tower RJ, Li Z, Cheng YH, Wang XW, Rajbhandari L, Zhang Q, Negri S, Uytingco CR, Venkatesan A, Zhou FQ, Cahan P, James AW, Clemens TL. Spatial transcriptomics reveals a role for sensory nerves in preserving cranial suture patency through modulation of BMP/TGF-β signaling Proceedings of the National Academy of Sciences of the United States of America. 118, 2021.
  • Wang XW, Yang SG, Zhang C, Hu MW, Qian J, Ma JJ, Zhang Y, Yang BB, Weng YL, Ming GL, Kosanam AR, Saijilafu, Zhou FQ. Knocking Out Non-muscle Myosin II in Retinal Ganglion Cells Promotes Long-Distance Optic Nerve Regeneration. Cell Reports. 31, 2020.
  • Costa AR, Sousa SC, Pinto-Costa R, Mateus JC, Lopes CD, Costa AC, Rosa D, Machado D, Pajuelo L, Wang X, Zhou FQ, Pereira AJ, Sampaio P, Rubinstein BY, Mendes Pinto I, Lampe M, Aguiar P, Sousa MM. The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction eLife. 9, 2020.
  • Wang XW, Li Q, Liu CM, Hall PA, Jiang JJ, Katchis CD, Kang S, Dong BC, Li S, Zhou FQ. Lin28 Signaling Supports Mammalian PNS and CNS Axon Regeneration Cell Reports. 24, 2018.