Davide Zella, PhD

Contact Info

• 3814 Spectrum Boulevard
  Tampa FL 33612
• Academic Email: dzella@usf.edu

Education

Research Interests

• Host-Microbiota interactions, Microbiome, Cancer Biology, Quantum Biology

Recent Publications

• Benedetti F, Silvestri G, Denaro F, Finesso G, Contreras-Galindo R, Munawwar A, Williams S, Davis H, Bryant J, Wang Y, Radaelli E, Rathinam CV, Gallo RC, Zella D Mycoplasma DnaK expression increases cancer development in vivo upon DNA damage Proceedings of the National Academy of Sciences of the United States of America. 121(10) , 2024.
• Benedetti F, Mongodin EF, Badger JH, Munawwar A, Cellini A, Yuan W, Silvestri G, Kraus CN, Marini S, Salemi M, Tettelin H, Gallo RC, Zella D. Bacterial DnaK reduces the activity of anti-cancer drugs cisplatin and 5FU Journal of Translational Medicine. 22(1) , 2024.
• Curreli S, Benedetti F, Yuan W, Munawwar A, Cocchi F, Gallo RC, Sherman NE and Zella D Characterization of the interactome profiling of Mycoplasma fermentans DnaK in cancer cells reveals interference with key cellular pathways Frontiers in Microbiology. 13, 2022.
• Benedetti F, Silvestri G, Saadat S, Denaro F, Latinovic OS, Davis H, Williams S, Bryant J, Ippodrino R, Rathinam CV, Gallo RC, Zella D. Mycoplasma DnaK increases DNA copy number variants in vivo Proceedings of the National Academy of Sciences of the United States of America. 120(30) , 2023.
• Benedetti F., Curreli S., Gallo R. C., Zella D. Exogenous bacterial DnaK increases protein kinases activity in human cancer cell lines Journal of Translational Medicine. 19(1) , 2021.
• Giovanetti M, Cella E, Benedetti F, Rife Magalis B, Fonseca V, Fabris S, Campisi G, Ciccozzi A, Angeletti S, Borsetti A, Tambone V, Sagnelli C, Pascarella S, Riva A, Ceccarelli G, Marcello A, Azarian T, Wilkinson E, de Oliveira T, Alcantara LCJ, Cauda R, Caruso A, Dean NE, Browne C, Lourenco J, Salemi M, Zella D, Ciccozzi M. SARS-CoV-2 shifting transmission dynamics and hidden reservoirs potentially limit efficacy of public health interventions in Italy Communications Biology. 4(1) , 2021.
• Benedetti F., Curreli S., Gallo R.C. and Zella D. Tampering of Viruses and Bacteria with Host DNA Repair: Implications for Cellular Transformation Cancers. 13(2) , 2021.
• Benedetti F, Snyder GA, Giovanetti M, Angeletti S, Gallo RC, Ciccozzi M, Zella D Emerging of a SARS-CoV-2 viral strain with a deletion in nsp1 Journal of Translational Medicine. 18(1) , 2020.
• 53. Pachetti M, Marini B, Benedetti F, Giudici F, Mauro, E, Storici P, Masciovecchio C, Angeletti S, Ciccozzi M, Gallo RC, Zella D, Ippodrino R Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant Journal of Translational Medicine. 18(1) , 2020.
• Denaro F, Benedetti F, Worthington MD, Scapagnini G, Krauss CC, Williams S, Bryant J, Davis H, Latinovic OS, Zella D. The HIV-1 Transgenic Rat: Relevance for HIV Noninfectious Comorbidity Research Microorganisms. 8(11) , 2020.
• Zella D, Curreli S, Benedetti F, Krishnan S, Cocchi F, Latinovic OS, Denaro F, Romerio F, Djavani M, Charurat ME, Bryant JL, Tettelin H, Gallo RC. Mycoplasma promotes malignant transformation in vivo, and its DnaK, a bacterial chaperone protein, has broad oncogenic properties Proceedings of the National Academy of Sciences of the United States of America. 115(51) , 2018.
• Zella D., Romerio F., Curreli S., Secchiero P., Zagury D. and Gallo R.C. IFN-alpha2b reduces IL-2 production and IL-2 receptor function in primary CD4+ T-cells J Immunol.. 164, 2000.