Clinical trials that seek to improve treatment outcomes in patients with colon and rectal cancer, inflammatory bowel disease, surgical Infection.
Memberships
Fellow (American Society of Colon and Rectal Surgeons, 1994 - Present)
Fellow (American College of Surgeons, 1993 - Present)
Recent Publications
Gao X, DeSantis AJ, Enten GA, Weche M, Marcet JE, Majetschak M. Heteromerization between α -adrenoceptor and chemokine (C-C motif) receptor 2 biases α -adrenoceptor signaling: Implications for vascular function.FEBS letters. 596(20) : 2706-2716, 2022.
Garcia-Aguilar J, Patil S, Gollub MJ, Kim JK, Yuval JB, Thompson HM, Verheij FS, Omer DM, Lee M, Dunne RF, Marcet J, Cataldo P, Polite B, Herzig DO, Liska D, Oommen S, Friel CM, Ternent C, Coveler AL, Hunt S, Gregory A, Varma MG, Bello BL, Carmichael JC, Krauss J, Gleisner A, Paty PB, Weiser MR, Nash GM, Pappou E, Guillem JG, Temple L, Wei IH, Widmar M, Lin S, Segal NH, Cercek A, Yaeger R, Smith JJ, Goodman KA, Wu AJ, Saltz LB. Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy.Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40(23) : 2546-2556, 2022.
Silinsky JD, Marcet JE, Anupindi VR, Karkare SU, Shah DR, Mack RJ, McCallum SW, Du W, Freyer A, Black LK. Preoperative intravenous meloxicam for moderate-to-severe pain in the immediate post-operative period: a Phase IIIb randomized clinical trial in 55 patients undergoing primary open or laparoscopic colorectal surgery with bowel resection and/or anastomosis.Pain management. 11(1) : 9-21, 2021.
Satava RM, Stefanidis D, Levy JS, Smith R, Martin JR, Monfared S, Timsina LR, Darzi AW, Moglia A, Brand TC, Dorin RP, Dumon KR, Francone TD, Georgiou E, Goh AC, Marcet JE, Martino MA, Sudan R, Vale J, Gallagher AG. Response to the Comment on "Proving the Effectiveness of the Fundamentals of Robotic Surgery (FRS) Skills Curriculum: A Single-blinded, Multispecialty, Multi-institutional Randomized Control Trial: Not Only Surgeon''s Manual Skills..."Annals of surgery. 274(6) : e847-e848, 2021.
Satava RM, Stefanidis D, Levy JS, Smith R, Martin JR, Monfared S, Timsina LR, Darzi AW, Moglia A, Brand TC, Dorin RP, Dumon KR, Francone TD, Georgiou E, Goh AC, Marcet JE, Martino MA, Sudan R, Vale J, Gallagher AG. Proving the Effectiveness of the Fundamentals of Robotic Surgery (FRS) Skills Curriculum: A Single-blinded, Multispecialty, Multi-institutional Randomized Control Trial.Annals of surgery. 272(2) : 384-392, 2020.
Sands BE, Sandborn WJ, Panaccione R, O''Brien CD, Zhang H, Johanns J, Adedokun OJ, Li K, Peyrin-Biroulet L, Van Assche G, Danese S, Targan S, Abreu MT, Hisamatsu T, Szapary P, Marano C. Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis.The New England journal of medicine. 381(13) : 1201-1214, 2019.
Bergese SD, Melson TI, Candiotti KA, Ayad SS, Mack RJ, McCallum SW, Du W, Gomez A, Marcet JE. A Phase 3, Randomized, Placebo-Controlled Evaluation of the Safety of Intravenous Meloxicam Following Major Surgery.Clinical pharmacology in drug development. 8(8) : 1062-1072, 2019.
Karlnoski R, Abboud EC, Thompson P, Oxner AZ, Sinnott JT, Marcet JE. Reduction in Central Line-Associated Bloodstream Infections Correlated With the Introduction of a Novel Silver-Plated Dressing for Central Venous Catheters and Maintained for 6 Years.Journal of intensive care medicine. 34(7) : 544-549, 2019.
Marco MR, Zhou L, Patil S, Marcet JE, Varma MG, Oommen S, Cataldo PA, Hunt SR, Kumar A, Herzig DO, Fichera A, Polite BN, Hyman NH, Ternent CA, Stamos MJ, Pigazzi A, Dietz D, Yakunina Y, Pelossof R, Garcia-Aguilar J. Consolidation mFOLFOX6 Chemotherapy After Chemoradiotherapy Improves Survival in Patients With Locally Advanced Rectal Cancer: Final Results of a Multicenter Phase II Trial.Diseases of the colon and rectum. 61(10) : 1146-1155, 2018.
Bennett-Guerrero E, Minkowitz HS, Segura-Vasi AM, Marcet JE, White JA, Corey GR, Allenby KS. A randomized, double-blind, placebo controlled safety, tolerability, and pharmacokinetic dose escalation study of a gentamicin vancomycin gel in patients undergoing colorectal surgery.Perioperative medicine (London, England). 5: 17, 2016.
Garcia-Aguilar J, Renfro LA, Chow OS, Shi Q, Carrero XW, Lynn PB, Thomas CR, Chan E, Cataldo PA, Marcet JE, Medich DS, Johnson CS, Oommen SC, Wolff BG, Pigazzi A, McNevin SM, Pons RK, Bleday R. Organ preservation for clinical T2N0 distal rectal cancer using neoadjuvant chemoradiotherapy and local excision (ACOSOG Z6041): results of an open-label, single-arm, multi-institutional, phase 2 trial.The Lancet. Oncology. 16(15) : 1537-1546, 2015.
Garcia-Aguilar J, Chow OS, Smith DD, Marcet JE, Cataldo PA, Varma MG, Kumar AS, Oommen S, Coutsoftides T, Hunt SR, Stamos MJ, Ternent CA, Herzig DO, Fichera A, Polite BN, Dietz DW, Patil S, Avila K. Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.The Lancet. Oncology. 16(8) : 957-66, 2015.
Mellgren A Zutshi M Lucente VR Culligan P Fenner DE; TRANSFORM Study
Group. A posterior anal sling for fecal incontinence: results of a 152-patient prospective
multicenter studyAm J Obstet Gynecol. (15) : 01276-4, 2015.
Charlton ME, Mattingly-Wells LR, Marcet JE, McMahon Waldschmidt BC, Cromwell JW. Association between surgeon characteristics and their preferences for guideline-concordant staging and treatment for rectal cancer.American journal of surgery. 208(5) : 817-823, 2014.
Greene KA, Sanchez JE, Campbell ML, Marcet JE. Robot-assisted rectopexy and colpopexy for rectal prolapse.International Urogynecology Journal. 25(4) : 553-5, 2014.
Hartney M Liu Y Velanovich V Fabri P Marcet J Grieco M Huang S Zayas-Castro J. Bounceback branchpoints: using conditional inference trees to analyze readmissions.Surgery. 156(4) : 842-7, 2014.
Abboud EC, Legare TB, Settle JC, Boubekri AM, Barillo DJ, Marcet JE, Sanchez JE. Do silver-based wound dressings reduce pain? A prospective study and review of the literature.Burns : journal of the International Society for Burn Injuries. 40 Suppl 1: S40-7, 2014.
Abboud EC, Settle JC, Legare TB, Marcet JE, Barillo DJ, Sanchez JE. Silver-based dressings for the reduction of surgical site infection: review of current experience and recommendation for future studies.Burns : journal of the International Society for Burn Injuries. 40 Suppl 1: S30-9, 2014.
Cohen SM, Vogel JD, Marcet JE, Candiotti KA. Liposome bupivacaine for improvement in economic outcomes and opioid burden in GI surgery: IMPROVE Study pooled analysis.Journal of pain research. 7: 359-66, 2014.
Campbell ML, Abboud EC, Dolberg ME, Sanchez JE, Marcet JE, Rasheid SH. Treatment of refractory perianal fistulas with ligation of the intersphincteric fistula tract: preliminary results.The American surgeon. 79(7) : 723-7, 2013.
Sandborn WJ, Feagan BG, Rutgeerts P, Hanauer S, Colombel JF, Sands BE, Lukas M, Fedorak RN, Lee S, Bressler B, Fox I, Rosario M, Sankoh S, Xu J, Stephens K, Milch C, Parikh A. Vedolizumab as induction and maintenance therapy for Crohn''s disease.The New England journal of medicine. 369(8) : 711-21, 2013.
Marcet JE, Nfonsam VN, Larach S. An extended paIn relief trial utilizing the infiltration of a long-acting Multivesicular liPosome foRmulation Of bupiVacaine, EXPAREL (IMPROVE): a Phase IV health economic trial in adult patients undergoing ileostomy reversal.Journal of Pain Research. 6: 549-55, 2013.
Nfonsam V Mateka J Prather A Marcet J. Short-term outcomes of the surgical
management of acquired rectourethral fistulas: does technique matter?Research and Reports in Urology. 5: 47-51, 2013.
Candiotti KA Sands LR Lee E Bergese SD Harzman AE Marcet J Kumar A Haas E. Liposome Bupivacaine for Postsurgical Analgesia in Adult Patients Undergoing
Laparoscopic Colectomy: Results from Prospective Phase IV Sequential Cohort Studies
Assessing Health Economic Outcomes.Curr Ther Res Clin Exp. 76: 1-6, 2013.
Sandborn WJ Feagan BG Rutgeerts P Hanauer S Colombel JF Sands BE Lukas M
Fedorak RN Lee S Bressler B Fox I Rosario M Sankoh S Xu J Stephens K Milch C
Parikh A, GEMINI 2 Study Group. Vedolizumab as induction and maintenance therapy
for Crohn''s disease.N Engl J Med. 369(8) : 711-21, 2013.
Sanchez JE, Marcet JE. Colorectal natural orifice transluminal endoscopic surgery (NOTES) and transvaginal/transrectal specimen extraction.Techniques in coloproctology. 17 Suppl 1: S69-73, 2013.
Campbell ML, Vadas KJ, Rasheid SH, Marcet JE, Sanchez JE. A reproducible ex vivo model for transanal minimally invasive surgery.JSLS : Journal of the Society of Laparoendoscopic Surgeons / Society of Laparoendoscopic Surgeons. 18(1) : 62-5, 2013.
Emtage JB, Parker J, Marcet JE, Finan J, Lockhart JL, Hernandez DJ. A large cellular angiofibroma of the male pelvis presenting with obstructive voiding: A case report and review of the literature.Canadian Urological Association journal = Journal de l''Association des urologues du Canada. 7(5) : E373-5, 2013.
Garcia-Aguilar J, Shi Q, Thomas CR, Chan E, Cataldo P, Marcet J, Medich D, Pigazzi A, Oommen S, Posner MC. A phase II trial of neoadjuvant chemoradiation and local excision for T2N0 rectal cancer: preliminary results of the ACOSOG Z6041 trial.Annals of surgical oncology. 19(2) : 384-91, 2012.
Spinelli N, Nfonsam V, Marcet J, Velanovich V, Frattini JC. Postoperative pneumoperitoneum after colorectal surgery: Expectant vs surgical management.World Journal of Gastrointestinal Surgery. 4(6) : 152-6, 2012.
Krieger BR, Davis DM, Sanchez JE, Mateka JJ, Nfonsam VN, Frattini JC, Marcet JE. The use of silver nylon in preventing surgical site infections following colon and rectal surgery.Diseases of the colon and rectum. 54(8) : 1014-9, 2011.
Davis DM, Marcet JE, Frattini JC, Prather AD, Mateka JJ, Nfonsam VN. Is it time to lower the recommended screening age for colorectal cancer?Journal of the American College of Surgeons. 213(3) : 352-61, 2011.
Garcia-Aguilar J, Chen Z, Smith DD, Li W, Madoff RD, Cataldo P, Marcet J, Pastor C. Identification of a biomarker profile associated with resistance to neoadjuvant chemoradiation therapy in rectal cancer.Annals of surgery. 254(3) : 486-92; discussion 492-3, 2011.
Graf W, Mellgren A, Matzel KE, Hull T, Johansson C, Bernstein M. Efficacy of dextranomer in stabilised hyaluronic acid for treatment of faecal incontinence: a randomised, sham-controlled trial.Lancet (London, England). 377(9770) : 997-1003, 2011.
Bennett-Guerrero E, Pappas TN, Koltun WA, Fleshman JW, Lin M, Garg J, Mark DB, Marcet JE, Remzi FH, George VV, Newland K, Corey GR. Gentamicin-collagen sponge for infection prophylaxis in colorectal surgery.The New England journal of medicine. 363(11) : 1038-49, 2010.
Rehg KL, Sanchez JE, Krieger BR, Marcet JE. Fecal diversion in perirectal fistulizing Crohn''s disease is an underutilized and potentially temporary means of successful treatment.The American surgeon. 75(8) : 715-8, 2009.
Nair RM, Siegel EM, Chen DT, Fulp WJ, Yeatman TJ, Malafa MP, Marcet J, Shibata D. Long-term results of transanal excision after neoadjuvant chemoradiation for T2 and T3 adenocarcinomas of the rectum.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 12(10) : 1797-805; discussion 1805-6, 2008.
Rezania D, Ouban A, Marcet J, Kelley S, Coppola D. CMV colitis mimicking recurrent inflammatory bowel disease: report of three cases.The American surgeon. 73(1) : 58-61, 2007.
Cromwell JW, Santiago LT, Marcet JE. Treatment of rectal cancer.The New England journal of medicine. 355(23) : 2487; author reply 2487-8, 2006.
Kelley ST, Coppola D, Yeatman T, Marcet J. Tumor response to neoadjuvant chemoradiation therapy for rectal adenocarcinoma is mediated by p53-dependent and caspase 8-dependent apoptotic pathways.Clinical colorectal cancer. 5(2) : 114-8, 2005.
Nasir A, Boulware D, Kaiser HE, Bodey B, Siegel S, Crawley S, Yeatman T, Marcet JE, Coppola D. Flat and polypoid adenocarcinomas of the colorectum: A comparative histomorphologic analysis of 47 cases.Human pathology. 35(5) : 604-11, 2004.
