Anthony DeSantis, MD

Assistant Professor, College of Medicine Surgery

Contact Info

• 1 Tampa General Circle, G-417
  Tampa FL
• Academic Email: adesanti@usf.edu

Education

Biography

Dr DeSantis is board certified in general surgery and surgical critical care. As an acute care surgeon at the University of South Florida, he specializes in trauma surgery, emergency general surgery, and critical care. He received his bachelor's degree from Florida State University, after which he was commissioned into the United States Marine Corps, where he served as an Infantry Officer with deployments to the middle east and the western pacific. Following his military service, he completed medical school and general surgery residency training at the University of South Florida, to include an additional two years as a post-doctoral research fellow studying hemorrhagic shock and resuscitation. Following residency, he then completed fellowship training in surgical critical care and acute care surgery at the R Adams Cowley Shock Trauma Center at the University of Maryland - Baltimore. He cares for patients at the University's primary teaching affiliate, Tampa General Hospital.

Recent Publications

• Burke EG, DeSantis AJ, et al. Mechanism-Stratified Complications After Operative Management of Low-Grade Colon Injuries Journal of Surgical Research. 321 : 452-460, 2026.
• DeSantis, Anthony J|Harfouche, Melike|Namias, Nicholas Are the life-saving interventions really life-saving? Trauma Surgery & Acute Care Open [23975776]. 10(Suppl 3), 2025.
• Fitzgerald CA, DeSantis AJ, et al. Primary repair versus resection for American Association for the Surgery of Trauma grades I and II colon injuries: Does the management approach really matter? An Eastern Association for the Surgery of Trauma multicenter trial. J Trauma Acute Care Surg.. (99) : 105-112, 2025.
• DeSantis AJ, Harfouche M, Namias N. Are the life-saving interventions really life-saving? Trauma Surg Acute Care Open. 10 : e001545, 2025.
• Sujka, J, DeSantis AJ, et al. Developing reliable surgery-specific entrustable professional activities (SSEPA) for the fourth year of medical school. Global Surg Educ. 3(108), 2024.
• Weche M, DeSantis AJ, McGee MY, Enten GA, Gao X, Majetschak M Effects of chemokine (C-C motif) receptor 2 and 3 antagonists in rat models of hemorrhagic shock PLoS One. 18(4) : e0284472, 2023.
• Gao X, DeSantis AJ, Enten GA, Weche M, Marcet JE, Majetschak M Heteromerization between α1B-adrenoceptor and chemokine (C-C motif) receptor 2 biases α1B-adrenoceptor signaling: Implications for vascular function FEBS Letters. 596(20) : 2706–2716, 2022.
• DeSantis AJ, Weche M, Enten GA, Gao X, Majetschak M The Chemokine (C-C Motif) Receptor 2 Antagonist INCB3284 Reduces Fluid Requirements and Protects from Hemodynamic Decompensation During Resuscitation From Hemorrhagic Shock Critical Care Explorations. 4(5) : e0701, 2022.