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* (Molecular Medicine Faculty Profile)

Eric Lewandowski

Eric Lewandowski, PhD

Senior Research Scientist, College of Medicine Molecular Medicine

Contact Info

Education

  • PhD, Medical Sciences, University of South Florida*, 2015
  • MS, Medical Science, University of South Florida, 2008
  • BS, Microbiology and Cell Science, University of Florida, 2007

Research Interests

  • Our lab focuses on structure based drug design through the use of X-ray crystallography and molecular docking.
  • My research is focused on discovering novel inhibitors of the protein monofunctional transglycosylase (MTG). MTG catalyzes the second to last step of bacterial cell wall formation and has only one known inhibitor, but unfortunately it is ineffective in humans. By combining fragment based molecular docking with protein X-ray crystallography I hope to discover novel inhibitors against MTG and other transglycosylases involved in bacterial cell wall formation. These novel inhibitors could lead to a new class of antibiotic that would ultimately be effective against bacteria that are resistant to many currently available drugs.