PhD, Biomedical Science, University of Florida, 2010
BS, Neuroscience, University of Pittsburgh, 2005
Interdisciplinary and Emerging Signature Programs
Allergy, Immunology & Infectious Disease
Cardiovascular Sciences
Cellular and Molecular Biology
Neuroscience
Research Interests
My laboratory uses in vitro and in vivo models of acute CNS injury to investigate novel cell signaling mechanisms contributing to axonal and neuronal damage in the brain. We use transgenic mice, lentivirus-based approaches, and experimental small-molecule drugs to study potential neuroprotective therapies. Germane to specific targets of interest, we are currently funded by the National Institute of Neurological Disorders and Stroke (NINDS) on a project to elucidate the role of the pro-death splicing factor RNA binding motif 5 (RBM5) in traumatic brain injury (TBI). In addition, my laboratory is developing potential strategies to enhance the neuroprotective efficacy of therapeutic hypothermia (TH). Namely, we are investigating methods to optimize the induction of cold-shock proteins (CSPs) and cold-stress hormones (CSHs), to increase the benefits of cerebroprotective cooling.
Recent Publications
Jackson TC, Herrmann JR, Garman RH, Kang RD, Vagni VA, Gorse K, Janesko-Feldman K, Stezoski J, Kochanek PM Hypoxia-ischemia-mediated effects on neurodevelopmentally regulated cold-shock proteins in neonatal mice under strict temperature controlPediatric Research. , 2022.
Farooq J Snyder K, Janesko-Feldman K, Gorse K, Vagni V, Kochanek PM, Jackson T RNA Binding Motif 5 Gene Deletion Modulates Cell Signaling in a Sex-Dependent Manner but not Hippocampal Cell DeathJ Neurotrauma. , 2022.
Jackson T, C, Gorse K, Herrmann J, R, et al, . Hippocampal and Prefrontal Cortical Brain Tissue Levels of Irisin and GDF15 Receptor Subunits in ChildrenMol Neurobiol. , 2021.
Jeremy R, Herrmann
Ericka L, Fink
Anthony Fabio
Alicia K, Au
Rachel P, Berger
Keri Janesko-Feldman
Robert S, B, Clark
Patrick M, Kochanek
Travis C, Jackso. Serum levels of the cold stress hormones FGF21 and GDF-15 after cardiac arrest in infants and children enrolled in single center therapeutic hypothermia clinical trialsAdvanced Online Publication. , 2021.
Travis C, Jackson Keri Janesko-Feldman Shaun W Carlson Shawn E Kotermanski Patrick M Kockanek. Robust RBM3 and β-klotho expression in developing neurons in the human brainSage Journals. , 2019.
