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AOA 2015 Postgraduate Awards
Johnny Nguyen, MD
USF Health Morsani College of Medicine
Project Category: Research
Understanding the Relationship between Genetic Basis and Immunomodulation in Myelodysplastic Syndromes and Related Myeoloid Neoplasms: Focusing on p53, EZH2 and Some Dendritic Cell Markers
Ling Zhang, MD, mentor
Myelodysplastic syndromes (MDS) are a group of diverse clonal hematopoietic stem cell disorders characterized by ineffective hematopoiesis and an increased risk of progression to acute myeloid leukemia that occur in a variety of patient populations. Next-generation sequencing (NGS) has detected novel gene mutations and abnormalities that contribute to MDS. Our study focuses specifically on TP53 and EZH2 mutations and their application to clinical outcomes. We are also examining dendritic cells, which are antigen presenting cells that forms part of the cellular backbone structure of the bone marrow itself, in its relation to MDS.
AOA 2014 Carolyn L. Kuckein Student Research Fellowships
Class of 2015, USF Health Morsani College of Medicine
Comparing Whole Slide Digital Images versus Traditional Glass Slides in the Detection of Common
Microscopic Features Seen in Dermatitis
Mentor Drazen M. Jukic, MD, PhD
Councilor Patricia J. Emmanuel, MD