Bernd Sokolowski, PhD
Professor, College Of Medicine Molecular Pharmacology & Physiology
Professor, College Of Medicine Otolaryngology
College Of Medicine Otolaryngology
Promotion and Tenure Committee, Department of Otolaryngology, University of South Florida - College of Medicine
Professor, Department of Otolaryngology, University of South Florida
Research Director, Department of Otolaryngology Head and Neck Surgery; (joint) Molecular Pharmacology and physiology, University of South Florida
Chairman, Research Committee., Department of Otolaryngology, University of South Florida
Assistant Professor, Department of Surgery; Division of Otolayngology; (joint) Department of Physiology & Biophysics, University of South Florida
Adjunct Faculty Committee., Department of Otolaryngology, University of South Florida
12901 Bruce B. Downs Blvd.
Otology Laboratory, MDC83
Academic Email: email@example.com
Academic Phone: (813) 974-5988
- PHD, Anatomy/Cell Biology, Georgetown University, 1985
- B.S., Zoology, University of Maryland, 1980
- M.A., Experimental Psychology, Towson University, 1978
- B.A., Psychology, University of Maryland, 1975
- Darville, LN.Sokolowski, BH. Bottom-up and shotgun proteomics to identify a comprehensive cochlear proteome. Journal of visualized experiments : JoVE. (85) , 2014. http://www.ncbi.nlm.nih.gov/pubmed/24638115
- Peng, Z.Sakai, Y.Kurgan, L.Sokolowski, B.Uversky, V. Intrinsic disorder in the BK channel and its interactome. PloS one. 9(4) : e94331, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24727949
- Ding, B.Frisina, RD.Zhu, X.Sakai, Y.Sokolowski, B.Walton, JP. Direct control of Na(+)-K(+)-2Cl(-)-cotransport protein (NKCC1) expression with aldosterone. American journal of physiology. Cell physiology. 306(1) : C66-75, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24173102
- Darville, LN.Sokolowski, BH. In-depth proteomic analysis of mouse cochlear sensory epithelium by mass spectrometry. Journal of proteome research. 12(8) : 3620-30, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23721421
- Sokolowski, S.Harvey, M.Sakai, Y.Jordan, A.Sokolowski, B. The large conductance calcium-activated K(+) channel interacts with the small GTPase Rab11b. Biochemical and biophysical research communications. 426(2) : 221-5, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22935415
- Sakai Y, Harvey M, Sokolowski BHA Identification and quantification of full-length BK channel variants in the developing mouse cochlea. J Neuroscience Research. (89) : 1747-1760, 2011.
- Sokolowski BHA, Orchard S, Harvey M, Sridhar S, Sakai Y Conserved BK interactions relevant to cell death and survival. PLoS ONE PLoS ONE. 12(6) , 2011.
- Sokolowski BHA, Orchard S Exploiting Protein Interaction Networks to Unravel Complex Biological Questions. Bioinformatics. IV(Book Chapter in Vienna, Austria in Press) : ISBN978-953-307-281-4, 2011.
- Harvey MC, Karolat J, Sakai Y, Sokolowski BHA PPTX a pentraxin domain-containing protein interacts with the T1 domain of Kv4. Neurosci Res.. 8(87) : 1841-1847, 2009.
- Sokolowski B, Duncan RK, Chen S, Karolat J, Kathiresan T, The large conductance Ca2+- activated K+ channel interacts with apolopoprotie ApoA1. Biochem Biophys Res Commun. 4(387) : 671-5, 2009.
- Kathiresan T, Orchard S, Harvey MC, Sokolowski BHA, A protein interaction network for the large conductance Ca2+ -activated K+ channel in the mouse cochlea. Mol Cell Proteomics. 8(8) : 1972-87, 2009.
- Kathiresan, T.Harvey, MC.Sokolowski, BH. The use of 2-D gels to identify novel protein-protein interactions in the cochlea. Methods in molecular biology (Clifton, N.J.). 493: 269-86, 2009. http://www.ncbi.nlm.nih.gov/pubmed/18839353
- Harvey, MC.Sokolowski, BH. In vivo verification of protein interactions in the inner ear by coimmunoprecipitation. Methods in molecular biology (Clifton, N.J.). 493: 299-310, 2009. http://www.ncbi.nlm.nih.gov/pubmed/18839355
- Sokolowski BHA, (ed) Humana Press/Springer Protocalls. Auditory/Vestibular Research, Methods and Protocol. (Book Chapter in New, NewYork) : 493:420, 2009.
- Levic S, Nie L, Harvey M, Sokolodki BHA, Yamoah EN Development and regeneration of hair cells share common functional features. Proc National Aaca Sci. 48(104) : 19108-19113, 2007.
- Gabashvili IS, Sokolowsk BHA, Morton CC, Giersch ABS Ion channel gene expression in the inner ear. JARO. 3(8) : 305-328, 2007.
- Sokolowski BHA Survey of inward currents acquired by the cochleovestibular
ganglion of the early-aged embryonic chick. J Neurosci Res.. 1(83) : 638-646, 2006.
- Hotchkiss K, Harvey M,WProblem: Electrical activity in hair cells and neurons of the inner ear is necessary for the transduction and modulation of stimuli impinging on the cochlea and vestibular endorgans of the inner ear. The underlying bases of this activity are pore-forming proteins in the membrane of excitable cells that allow the influx and efflux of various ions including Na+, Ca2+, and K+, among others. These channels are critical to both electrical activity and the development of excitable cells since they may initiate long-term signals important in the maintenance and survival of these cells. We investigate the expression of Shaker and Shal potassium ion channel proteins in the vestibular endorgans of mammalian species including mouse and human.Sokolowski BHA Ion channels in the vestibular tissue of mouse and human. Otolaryngology Head and Neck Surgery. 6(32) : 916-92, 2005.
- Duzhyy DE, Harvey MC, Sokolowski BHA A secretory type protien interacts with an A type potassium channel. J.Biol Chem. 15(280) : 15165-15172, 2005.
- Sokolowki BHA, Harvey M, Venkataramu C, Duzhyy D Ptotein-protein interactions of Kvbeta subunit in the cochlea. J Neurosci Res.. 4(79) : 459-467, 2005.
- Sokolowki BHA, Sakai Y, Harvey MC, Duzhyy DE Identification and localization of an arachidonic acid sensitive potassium channel in the cochlea. J. Neurosci. (24) : 6265-6276, 2004.
- Sokolowski BHA Sensory Systems. In XPharm: The Comprehensive Pharmacology Reference (Eds. S.J. Enna, David B. Bylund), Elsevier, Inc., New York, NY.. , 2004.
- Duzhyy DE, Sokolwski BHA Cloning and Developmental expression of "Shaker" potassium channels in the cochlea of the chick. Mol Brain Res.. 121: 70, 2004.
- Rajeeven MS, Hu S., Sakai Y ,Sokolowsi BHA, Cloning and expression of "Shaker"a and b-subunits during inner ear development. Brain Res. Mol Brain Res.. (66) : 83-96, 1999.
- Sokolowski BHA, Csus' J, Hafez Ol Neurotrophic factors
modulate hair cells and their potassium currents in chick otocyst explants. Eur J Neurosci. (11) : 682-692, 1999.
- Sokolowsi BHA, Cunningham AM Patterns of synaptophysin expression during developement of the inner ear in the chick. J. Neurobial. 1(38) : 46-64, 1999.
- Sokolowski BHA Excitatory characterisitcs of cells during development of the inner ear. In Proceedings of the International Békésy Centenary Conference on Hearing and Related Sciences. 22(Book Chapter in Nyomdajaban 3526 Miskolc, Blaskovics) : 41-58, 1999.
- Sokolowski BHA Quantitative analysis of long-term survival and neuritogenesis in vitro: Cochlear vestibular ganglion of the chick embryo in BDNF, NT-3, NT-4/5 ND insulin. Exp. Neurol. 1(145) : 1-15, 1997.
- Sokolowski BHA, Cunnungham AM Sensory cells of the chick cochlea express synaptophysin. NeurosciLetts. (216) : 89-92, 1996.
- Sokolowski BHA, Stahl LM, Fuchs PA Morphological and physiological developement of vestibular hair cells in the organ-cultured otocyst of the chick. Dev Biol. 1(155) : 134-146, 1993.
- Fuchs PA,Sokolowski BHA The acquisition during developement of Ca-activated potassium currents by cochlear hait cells of the chick. Proc R Soc Lond B.. (241) : 122-126, 1990.
- Sokolowski BHA, Goldstein J, Sachs MB Auditory nerve rate-level functions for two-tone stimuli: Possible relation to basilar membrane non-linearity. Hear Research. (241) : 115-124, 1989.
- Sachs MB, Winslow RL, Sokolowski BHA A computational model for rate-level functions from cat auditory-nerve fibers. Hear Research. (41) : 61-70, 1989.
- Sokolowski BHA, Popper AN A transmission electron microscopic study of the cellular fine structure in the developing saccule of the toadfish. Opsanus tau.J Morphol. 1(198) : 49-69, 1988.
- Sokolowski BHA, Popper AN The gross and ultrastructural developement of the saccule of the embryonic and post-embryonic toadfish. Opsanus rau.J Morphol. (194) : 232-348, 1987.
- Sokolowski BHA Development of the Otolith in embryonic fishes with special references to the toadfish. Opsanus tau. Scam Electron Microsp. (IV) : 1635-1648, 1986.
- Committee to form Executive Committee on Research and Education (Department of Otolaryngology, University of South Florida 2009 - 2009)
- Associat Professor (tenure) (Department of Otolaryngology Head & Neck Surgery; Dept. Physiology and Biophysics, University of South Florida 1999 - 2006)
- Assistant Professor (Department of Otolaryngology Head & Neck Surgery, Dept.of Physiology & Biophysics, University of South Florida 1998 - 1999)
- Postdoctoral Fellow (Department of Physiology and Biophysics, University of Colorado, Health Sciences Center 1988 - 1991)
- Postdoctoral Fellow (Department of Biomedical Engineering, Center for Hearing Sciences, The Johns Hopkins University, School of Medicine 1985 - 1988)