Morsani College of Medicine
Department of Molecular Medicine
Joint and Affiliate Faculty
Post-Doctorates / Research Associates
How To Apply
Master's of Science Program
Allergy, Immunology and Infectious Diseases
USF Health Byrd Alzheimer's Institute
Children's Research Institute (CRI)
Center for Drug Discovery and Innovation
H. Lee Moffitt Cancer Center
James A Haley Veteran's Hospital
Bay Pines VA Healthcare System
Professor, COLLEGE OF MEDICINE MOLECULAR MEDICINE
Research in the White laboratory is focused on how the malaria-related protozoa,
, grows and develops in its human host.
is an environmental pathogen of the central nervous system (class B bioterrorism agent), which causes an often fatal disease in people who are immunocompromised. Projects in our laboratory focus on how these parasites interact with their host cell to produce new progeny and establish persistent infections. Our studies employ a diverse and extensive array of genetic and biochemical approaches with special emphasis on whole-cell strategies that enable a global understanding of the biochemical pathways involved in parasite growth and development. From forward genetic approaches that allow essential protein factors to be identified by genetic complementation to cataloging gene clusters within the whole-cell transcriptome that are responsible for transduction of the parasite cell division cycle, we are uncovering novel pathways that hold the key to important parasite biology.
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Graduate Research Assistant, COLLEGE OF MEDICINE MOLECULAR MEDICINE
- Our lab focuses on the interactions of molecular chaperones with various proteins associated with neurodegenerative disorders. The main focus of the lab is exploring the relationship between the protein Tau and Alzheimer’s Disease, but we have also recently started to explore the relationship between Myocilin and the disease Glaucoma.
-My project focuses on understanding the relationship between Myocilin and the co-chaperone Grp-94 in the disease Glaucoma. Using novel Grp94 inhibitors, I will look at inhibiting Grp94’s interaction with myocilin leading to clearance from the eye, and a reduction of symptoms associated with Glaucoma.
Alzheimer's disease, drug discovery and general Neuroscience