Welcome to the Department of
To Discover, apply and disseminate knowledge of the molecular basis of health and disease.
To Translate, this knowledge into innovative tools for the diagnosis, treatment and prevention of disease.
To Train, and mentor future scientists and health care professionals.
To Provide, a collegial and scholarly environment where students, faculty and staff thrive.
- The focus of our research program is to understand three seemingly disparate levels of biological organization during gametogenesis and early development: the molecular signatures for totipotency at the beginning of life, their variation among species, and their involvement as mechanisms of evolutionary change. We use comparative genomics and wet-lab approaches to understand how and why speciation primarily affects reproduction and its functions. Our approach provides a conceptual framework for personalized genomic medicine in human reproductive health.
- The Tipparaju lab focuses on voltage-gated potassium channel subunits (Kvβ1 and 2) within the heart. Currently we are investigating the molecular and physiological roles of Kvβ1.1 and Kvβ2 subunits within the heart. We utilize both en vivo, including a genetically deleted mouse model and en vitro models to study the overall molecular and physiological roles.