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AlexeiEvsikov

Alexei Evsikov, PhD

Assistant Professor, COLLEGE OF MEDICINE MOLECULAR MEDICINE
  • The focus of our research program is to understand three seemingly disparate levels of biological organization during gametogenesis and early development: the molecular signatures for totipotency at the beginning of life, their variation among species, and their involvement as mechanisms of evolutionary change. We use comparative genomics and wet-lab approaches to understand how and why speciation primarily affects reproduction and its functions. Our approach provides a conceptual framework for personalized genomic medicine in human reproductive health.
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Ph.D. Students

BoskoStojanovski

Bosko Stojanovski

Technical and Paraprofessional, COLLEGE OF MEDICINE MOLECULAR MEDICINE
  • Research in our lab is aimed at studying the enzymological aspects of heme biosynthesis, particularly the initial enzyme of the pathway, 5-aminolevulinate synthase (ALAS), and the final enzyme, ferrochelatase. The main aim of my project is understanding how specific structural region of ALAS affect the enzymatic mechanism, kinetics, and conformational dynamics. Another area of interest is the characterization of the folding pathway of ALAS to its native state, as well as understanding the biochemical and biophysical properties of any stable, partially folded intermediates.
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LeonidBreydo

Leonid Breydo, Ph.D.

Research Associate, COLLEGE OF MEDICINE MOLECULAR MEDICINE
  • misfolding and aggregation of intrinsically disordered proteins
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