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Research Focus

Featured Faculty

KennethUgen

Kenneth Ugen, Ph.D.

Professor, COLLEGE OF MEDICINE MOLECULAR MEDICINE
  • My research focuses on applied and translational immunology
  • with the goal of developing and characterizing novel gene based
  • vaccines and therapies against infectious agents and cancer.
  • Previous funded work has centered on vaccine development
  • against neurodegenerative diseases such as Alzheimers Disease
  • as well as the development of vaccines and immunotherapeutics
  • against HIV. Current research emphasis is centering on methods
  • for delivering novel gene and peptide based therapies against cancer
  • Basic molecular and immunological methods are being used in the
  • lab to pursue these goals
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Education Programs

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Post Docs

LisaKirouac

Lisa Kirouac

Graduate Research Assistant, COLLEGE OF MEDICINE MOLECULAR MEDICINE
  • Our lab studies the pathogenesis of Alzheimer's disease (AD). Specifically, we are interested in the molecular mechanisms that lead to the aberrant cell cycle that is observed in the AD brain. We have found that the amyloid precursor protein (APP), a central protein in AD, is modified and pathogenically processed in a cell-cycle specific manner. Furthermore, we have found that APP induces expression of proteins such as ras and gamma-synuclein, which are involved in cellular proliferation. The aim of my research is to elucidate the mechanisms by which APP induces the expression of these proliferation-associated proteins and determine how it leads to neurodegeneration and cognitive decline.
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Ph.D. Students

JessicaChang

Jessica Chang, PhD

Postdoctoral Scholar Research, COLLEGE OF MEDICINE MOLECULAR MEDICINE
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