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Research Focus

Featured Faculty

RobertDeschenes

Robert Deschenes, Ph.D.

Professor, COLLEGE OF MEDICINE MOLECULAR MEDICINE
  • The Deschenes research group and collaborators are currently focused in two general areas. The first deals with the posttranslational modification and the subcellular localization of cancer signal transduction proteins. The second deals with stress signaling and the characterization of histidine kinases.
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Education Programs

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Post Docs

LisaKirouac

Lisa Kirouac

Graduate Research Assistant, COLLEGE OF MEDICINE MOLECULAR MEDICINE
  • Our lab studies the pathogenesis of Alzheimer's disease (AD). Specifically, we are interested in the molecular mechanisms that lead to the aberrant cell cycle that is observed in the AD brain. We have found that the amyloid precursor protein (APP), a central protein in AD, is modified and pathogenically processed in a cell-cycle specific manner. Furthermore, we have found that APP induces expression of proteins such as ras and gamma-synuclein, which are involved in cellular proliferation. The aim of my research is to elucidate the mechanisms by which APP induces the expression of these proliferation-associated proteins and determine how it leads to neurodegeneration and cognitive decline.
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Ph.D. Students

JonathanSabbagh

Jonathan Sabbagh, PhD

Postdoctoral Scholar Research, COLLEGE OF MEDICINE MOLECULAR MEDICINE
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