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ChadDickey

Chad Dickey, Ph.D.

Assoc Professor, COLLEGE OF MEDICINE MOLECULAR MEDICINE
  • Human cells, including neurons in the brain, contain thousands of proteins that must work in concert to produce or perform our actions. Breathing, running, talking, remembering….all of these things are coordinated by thousands of proteins every second in our cells. This is what we work on in the lab. Hidden among those thousands of proteins is a group of sentinels called chaperones that, by definition, ensure propriety of all of these other proteins in the cell. Without chaperones, nothing would work properly. In fact, our lab and others have begun to show that many if not all of human disease is in some way affected by chaperones. There are approximately 150 chaperones in humans and each of these could be a drug target for human diseases. In particular, our lab has focused on a group of more than 15 neurological degenerative diseases collectively termed “tauopathies", the most common being Alzheimer’s disease. We have also seen our work move into glaucoma and depression.
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JaredTur

Jared Tur

Graduate Research Assistant, COLLEGE OF MEDICINE MOLECULAR MEDICINE
  • The Tipparaju lab focuses on voltage-gated potassium channel subunits (Kvβ1 and 2) within the heart. Currently we are investigating the molecular and physiological roles of Kvβ1.1 and Kvβ2 subunits within the heart. We utilize both en vivo, including a genetically deleted mouse model and en vitro models to study the overall molecular and physiological roles.
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