Our Mission

Research Focus

Featured Faculty

BurtAnderson

Burt Anderson, Ph.D.

Professor, COLLEGE OF MEDICINE MOLECULAR MEDICINE
  • The primary focus of our laboratory is how facultative intracellular bacteria control expression of genes required for virulence. We currently study how Bartonella henselae regulates expression of genes required to mediate the unique vascular proliferation that is observed in patients infected with this bacterium. In addition, we are studying gene regulatory circuits required for virulence in Francisella tularensis.
Read More...

Education Programs

Ph.D. Program Master's Program Graduate Certificates Apply Now

Ph.D. Students

  • Our lab is focused on understanding palmitoylation, a post-translational modification of Ras (an oncogene implicated in ~30% of all cancers, and up to 90% in specific cancer types) involved in its localization to the plasma membrane where Ras elicits a majority of its activity.
  • My project focuses on understanding the regulation of Ras palmitoylation in three ways. Initially, I used a candidate based approach to screen for the enzyme responsible for Ras depalmitoylation. More recently, I have been screening mutants of the enzyme that palmitoylated Ras to see the effect of the mutations on activity, and finally, I will perform high-throughput inhibitor screens in an attempt to identify inhibitors of palmitoylation.
Read More...

Post Docs

LeonidBreydo

Leonid Breydo, Ph.D.

Research Associate, COLLEGE OF MEDICINE MOLECULAR MEDICINE
  • misfolding and aggregation of intrinsically disordered proteins
Read More...