Development of new measurement of low-frequency hearing

• Lichtenhan, J.T., Cooper, N.P., Guinan, J.J. (2013). “A new auditory threshold estimation technique for low frequencies: Proof of concept” Ear & Hearing. 34, 42-51.

Surgical innovation

• Lichtenhan, J.T., Hartsock, J.J., Dornhoffer, J., Donovan, K.M., Salt, A.N. (2016). “Drug delivery into the cochlear apex: Improved control to sequentially affect finely spaced regions along the entire length of the cochlear spiral” Journal of Neuroscience Methods.1;273:201-209.

• Valenzuela, C.V., Lee, C., Buchman, C.A., Lichtenhan, J.T. (2020). “Revised surgical approach to induced endolymphatic hydrops in the guinea pig” Journal of Visualized Experiments. Jun 4;(160).

Endolymphatic Hydrops

• Lichtenhan, J.T., Lee, C., Wenrich, K.A., Dubaybo, F. Wilson, U.S. (2017). “The Auditory Nerve Overlapped Waveform (ANOW) detects small endolymphatic manipulations that may go undetected by conventional measurements” Frontiers in Neuroscience. 11:405.

• Lee, C., Valenzuela, C.V., Goodman, S.S., Kallogjeri, D., Buchman, C.A., Lichtenhan, J.T. (2020). “Early Detection of Endolymphatic Hydrops using the Auditory Nerve Overlapped Waveform (ANOW)” Neuroscience. 15;425:251-266.

• Guinan, J.J. Jr., Lefler, S.M., Buchman, C.A., Goodman, S.S., Lichtenhan, J.T. (2021). “Altered mapping of sound frequency to cochlear place in ears with endolymphatic hydrops provide insight into the pitch anomaly of diplacusis” Scientific Reports. 11(1):10380.

Autism and Hyperacusis

• Wilson, U.S., Sadler, K.M., Hancock, K.E., Guinan, J.J. Jr., Lichtenhan, J.T. (2017). “Efferent inhibition strength is a Physiological Correlate of Hyperacusis in Children with Autism Spectrum Disorder” Journal of Neurophysiology. 118(2):1164-1172.

• Lefler, S.M., Duncan, R.K., Goodman, S.S., Guinan, J.J. Jr., Lichtenhan, J.T. (2021). “Measurements from ears with endolymphatic hydrops and 2-Hydroxypropyl-Beta-Cyclodextrin provide evidence that loudness recruitment can have a cochlear origin” Frontiers in Surgery, section Otorhinolaryngology - Head and Neck Surgery. Oct 5;8:687490.

Medial Olivocochlear Efferent Reflex

• Lichtenhan, J.T., Wilson, U.S., Hancock, K.E., Guinan, J.J. (2016). “Medial Olivocochlear Efferent Reflex Inhibition of Human Cochlear Nerve Responses” Hearing Research. 333:216-24.

Understanding the cellular and spatial origin of neural and otoacoustic emission measurements along the cochlear length

• Lichtenhan, J.T., Hartsock, J.J., Gill, R.M., Guinan, J.J., Salt, A.N. (2014). “The Auditory Nerve Overlapped Waveform (ANOW) Originates in the Cochlear Apex” Journal of the Association for Research in Otolaryngology. 15(3):395-411.

• Lee, C., Guinan, J.J., Jr., Rutherford, M.A., Kaf, W.A., Kennedy, K.M., Buchman, C.A., Salt, A.N., Lichtenhan, J.T. (2019). “Cochlear compound action potentials from high-level tone bursts originate from wide cochlear regions that are offset toward the most sensitive cochlear region” Journal of Neurophysiology. 121(3):1018-1033.

• Goodman, S.S., Lee, C., Guinan, J.J. Jr., Lichtenhan, J.T. (2020). “The Spatial Origins of Cochlear Amplification Assessed by Stimulus-Frequency Otoacoustic Emissions” Biophysical Journal, 118(5):1183-1195.