Dr. Cheng an Associate Professor in Department of Pharmaceutical Science, College of Pharmacy at the University of South Florida (USF). He received his first Ph.D. degree in computational medicinal chemistry in the Chinese Academy of Science in 2003. He obtained his second Ph.D. in computational biophysics in 2010 at the University of Virginia. He has also postdoc training at the University of Illinois at Urbana Champaign and Yale University. His research interests are in the areas of drug discovery and development using computational methods (including molecular docking, pharmacophore mapping, and machine learning). More specifically, his lab uses genomic data and chemoinformatics approaches to identify already approved drugs to treat a different disease (drug repurposing). Additionally, his lab uses genomic data and FDA Adverse Event Reporting System (FAERS) to investigate possible drug-drug interactions. Dr. Cheng has published over 60 research papers in prestigious journals including Nature, Neuron, J. Am. Chem. Soc, and J. Med. Chem. His work has been more than 2,300 times. Presently, Dr. Cheng is the editor-in-chief of the Open Bioinformatics Journal (Bentham Publisher) and has been serving as an editorial board member of several journals.
Y. Xu, L. Tanon-Reyes, F. Cheng, C. Bi, N. Ye, G. Wu. VGSCW: Second generation vector graph toolkit of genome synteny and collinearity. Genomics (2019).
M. Pham, F. Cheng, K. Ramachandran. A Comparison Study of Algorithms to Detect Drug-Adverse Event Associations: Frequentist, Bayesian, and Machine-Learning Approaches. Drug safety, 1-8 (2019).
N.W. Carris, A. Tsalatsanis, S.M. Tipparaju, F. Cheng, R.R. Magness, A. Kumar. Metformin’s impact on statin-associated muscle symptoms: An analysis of ACCORD study data and research materials from the NHLBI Biologic Specimen and Data Repository Information Coordinating Center. Diabetes, Obesity and Metabolism, 20:8 (2018)
C. Wang, Y. Xu, X. Wang, L. Zhang, S. Wei, Q. Ye, Y. Zhu, H. Yin, M. Nainwal, L. Tanon-Reyes, F. Cheng, T. Yin, N. Ye. Gesture: an online hand-drawing tool for gene expression pattern search. PeerJ, 6 (2018).
Y. Hu, Z. Fang, Y. Yang, D. Rohlsen-Neal, F. Cheng, J. Wang. Analyzing the genes related to nicotine addiction or schizophrenia via a pathway and network based approach. Scientific reports, 8 (1) (2018).
X. Wang, F. Cheng, D. Rohlsen, C. Bi, C. Wang, Y. Xu, S. Wei, Q. Ye, T. Yin, N. Ye. Organellar genome assembly methods and comparative analysis of horticultural plants. Horticulture research, 5 (1) (2018).
Y.Y. Luo, X.Y. Xiong, F. Cheng, Y.C. Gong, Z.L. Li, Y.P. Li. The targeting properties of folate-conjugated pluronic F127/poly (lactic-co-glycolic) nanoparticles. International journal of biological macromolecules, 105, 711-719 (2017).
J. Tur, S.L. Badole, F. Cheng, A. Das, R.C. Kukreja, S.M. Tipparaju. Corticosteroids and aldose reductase inhibitor Epalrestat modulates cardiac action potential via Kvβ1. 1 (AKR6A8) subunit of voltage-gated potassium channel. Molecular and cellular biochemistry, 436 (1-2) (2017).
N.W. Carris, F. Cheng, W.N. Kelly. The changing cost to prevent diabetes: A retrospective analysis of the Diabetes Prevention Program. Journal of the American Pharmacists Association, 57 (6) (2017).
X.Y. Xiong, X. Pan, L. Tao, F. Cheng, Z.L. Li, Y.C. Gong, Y.P. Li. Enhanced effect of folated pluronic F87-PLA/TPGS mixed micelles on targeted delivery of paclitaxel. International journal of biological macromolecules, 103 (2017).