Biology of Degenerative Diseases Lab
Funding
Overview
Our work has been funded by the National Institutes of Health (NIH), the Department of Veterans Affairs, the Alzheimer’s Association, and USF Health.
Current Funding:
Florida Department of Health Ed and Ethel Moore Alzheimer's Disease Research Program
The major goal of this project is to determine if chaperones affect tau seeding and release.
NIH/National Institute of Mental Health (NIA) RF1 Award
The major goal of this study is to determine how small heat shock proteins regulate tau inside and outside of the tau to affect tau release, uptake, and neurotoxicity.
Department of Veterans Affairs (VA) Merit Award
The major goal of this project is to develop strategies to deplete FKBP51 while deepening our understanding of FKBP51 biology, with the long-range goal of enhancing the psychological resiliency of our soldiers.
Alzheimer’s Association AARG Award
The major goal of this study is to determine the contribution of neurotoxicity mediated through ER stress in tauopathy and to investigate how ER chaperones can regulate this process.