Pulmonary, Critical Care & Sleep Medicine

Nirmal Sharma T-2367-2018

Nirmal Sharma, MD

Assistant Professor, Internal Medicine, Advanced Lung Diseases & Lung Transplantation

Contact Info 12901 Bruce B Downs Blvd
MDC 4009
Tampa FL

Academic Email: nirmalsharma@health.usf.edu

Academic Phone:(813) 974-5415

Education

  • Instructor, Lung Transplantation/ECMO, University of Alabama at Birmingham, 2017
  • Fellow, Pulmonary and Critical Care, University of Alabama at Birmingham, 2016
  • Resident, Internal Medicine, Albert Einstein College of Medicine(Jacobi), 2013
  • MBBS, Medicine, Stanley Medical College, 2008

Academic Philosophy

"Improving quality of care and patient outcomes through patient centered translational research."

Interdisciplinary and Emerging Signature Programs

  • Allergy, Immunology & Infectious Disease
  • Environmental & Global Health
  • Other
  • Pulmonary Physiology

Research Interests

  • Understanding the Role Lung Microbiome and Immune Regulation in Chronic Lung Allograft Dysfunction in Lung Transplant Recipients
  • Utilization and outcomes of Extracorporeal Life Support Technologies in Acute Lung Failure

Memberships

  • ELSO (Course Director, 2016 - Present)
  • ISHLT (Member/Associate Editor ISHLT links, 2015 - Present)
  • ATS (Member/MITT Committee, 2013 - Present)

Recent Publications

  • Fukumoto J, Leung J, Cox R, Czachor A, Parthasarathy PT, Lagishetty V, Mandry M, Hosseinian N, Patel P, Perry B, Breitzig MT, Alleyn M, Failla A, Cho Y, Cooke AJ, Galam L, Soundararajan R, Sharma N, Lockey RF, Kolliputi N. Oxidative stress induces club cell proliferation and pulmonary fibrosis in Atp8b1 mutant mice. Aging. 11(1) : 209-229, 2019. http://www.ncbi.nlm.nih.gov/pubmed/30636723
  • Lal CV, Olave N, Travers C, Rezonzew G, Dolma K, Simpson A, Halloran B, Aghai Z, Das P, Sharma N, Xu X, Genschmer K, Russell D, Szul T, Yi N, Blalock JE, Gaggar A, Bhandari V, Ambalavanan N. Exosomal microRNA predicts and protects against severe bronchopulmonary dysplasia in extremely premature infants. JCI insight. 3(5) : 11234, 2018. http://www.ncbi.nlm.nih.gov/pubmed/29515035
  • Hough KP, Wilson LS, Trevor JL, Strenkowski JG, Maina N, Kim YI, Spell ML, Wang Y, Chanda D, Dager JR, Sharma NS, Curtiss M, Antony VB, Dransfield MT, Chaplin DD, Steele C, Barnes S, Duncan SR, Prasain JK, Thannickal VJ, Deshane JS. Unique Lipid Signatures of Extracellular Vesicles from the Airways of Asthmatics. Scientific reports. 8(1) : 10340, 2018. http://www.ncbi.nlm.nih.gov/pubmed/29985427
  • Sharma NS, Lal CV, Li JD, Lou XY, Viera L, Abdallah T, King R, Sethi J, Kanagarajah P, Restrepo-Jaramillo R, Sales-Conniff A, Wei S, Jackson PL, Blalock JE, Gaggar A, Xu X. The Neutrophil Chemoattractant Peptide Proline-Glycine-Proline Is Associated With Acute Respiratory Distress Syndrome (ARDS). American journal of physiology. Lung cellular and molecular physiology. , 2018. http://www.ncbi.nlm.nih.gov/pubmed/30091378
  • Garcia B, Sharma N, Johnson K, Salgado J, Wille K. Clinical Outcomes of Paramyxovirus Infections in Lung Transplant Recipients Treated With Oral Ribavirin: A Two-Center Case Series. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation. , 2017. http://www.ncbi.nlm.nih.gov/pubmed/29108516
  • Sharma NS, Wille KM, Athira S, Zhi D, Hough KP, Diaz-Guzman E, Zhang K, Kumar R, Rangarajan S, Eipers P, Wang Y, Srivastava RK, Rodriguez Dager JV, Athar M, Morrow C, Hoopes CW, Chaplin DD, Thannickal VJ, Deshane JS. Distal airway microbiome is associated with immunoregulatory myeloid cell responses in lung transplant recipients. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. , 2017. http://www.ncbi.nlm.nih.gov/pubmed/28756121
  • Sharma NS, Hartwig MG, Hayes D. Extracorporeal membrane oxygenation in the pre and post lung transplant period. Annals of translational medicine. 5(4) : 74, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28275619
  • Sharma NS, Wille KM, Bellot SC, Diaz-Guzman E. Automated Rotational Percussion Bed and Bronchoscopy Improves Respiratory Mechanics and Oxygenation in ARDS Patients Supported with Extracorporeal Membrane Oxygenation. ASAIO journal (American Society for Artificial Internal Organs : 1992). 62(3) : e27-9, 2016. http://www.ncbi.nlm.nih.gov/pubmed/26771392
  • Kulkarni T, Sharma NS, Diaz-Guzman E. Extracorporeal membrane oxygenation in adults: A practical guide for internists. Cleveland Clinic journal of medicine. 83(5) : 373-84, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27168514
  • Diaz-Guzman E, Sharma NS, Wille K, Hoopes CW. Use of a novel pulmonary artery cannula to provide extracorporeal membrane oxygenation as a bridge to lung transplantation. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 35(8) : 1051-3, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27377218
  • Chanda D, Kurundkar A, Rangarajan S, Locy M, Bernard K, Sharma NS, Logsdon NJ, Liu H, Crossman DK, Horowitz JC, De Langhe S, Thannickal VJ. Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary Fibrosis. Scientific reports. 6: 37445, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27869174
  • Sharma NS, Peters T, Kulkarni T, Hoopes CW, Bellot SC, Wille KM, Diaz-Guzman E. Flexible Bronchoscopy Is Safe and Effective in Adult Subjects Supported With Extracorporeal Membrane Oxygenation. Respiratory care. 61(5) : 646-51, 2016. http://www.ncbi.nlm.nih.gov/pubmed/26814220
  • Sharma NS, Wille KM, Zhi D, Thannickal VJ, Brodie DM, Hoopes CW, Diaz-Guzman E. Use of ECMO in the Management of Severe Acute Respiratory Distress Syndrome: A Survey of Academic Medical Centers in the United States. ASAIO journal (American Society for Artificial Internal Organs : 1992). 61(5) : 556-63, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25914957
  • Sharma NS, Wille KM, Diaz Guzman E. Extracorporeal membrane oxygenation after liver transplantation in a patient with hepatopulmonary syndrome and an atrial septal defect. The International journal of artificial organs. 38(3) : 170-2, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25837880
  • Sharma NS, Wille KM, Bellot SC, Diaz-Guzman E. Modern use of extracorporeal life support in pregnancy and postpartum. ASAIO journal (American Society for Artificial Internal Organs : 1992). 61(1) : 110-4, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25248040
  • Teerapuncharoen K, Sharma NS, Barker AB, Wille KM, Diaz-Guzman E. Successful Treatment of Severe Carbon Monoxide Poisoning and Refractory Shock Using Extracorporeal Membrane Oxygenation. Respiratory care. 60(9) : e155-60, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25922545
  • Wille KM, Sharma NS, Kulkarni T, Lammi MR, Barney JB, Bellot SC, Cantor RS, Naftel DC, Diaz-Guzman E, McGiffin DC. Characteristics of patients with pulmonary venoocclusive disease awaiting transplantation. Annals of the American Thoracic Society. 11(9) : 1411-8, 2014. http://www.ncbi.nlm.nih.gov/pubmed/25296345
  • Sharma N, Venado A, Morrison J. Protocol-based treatment of septic shock, fibrinolysis for submassive pulmonary embolism, and use of corticosteroids in acute exacerbations of chronic obstructive pulmonary disease requiring mechanical ventilation. American journal of respiratory and critical care medicine. 190(7) : 827-8, 2014. http://www.ncbi.nlm.nih.gov/pubmed/25271746
  • Sharma NS, Wille KM, Hoopes CW, Diaz-Guzman E. Acute demyelinating polyneuropathy after lung transplantation: guillain-barrĂ© syndrome or tacrolimus toxicity? Case reports in transplantation. 2014: 685010, 2014. http://www.ncbi.nlm.nih.gov/pubmed/25184071
  • Chopra A, Shim C, Sharma N, Gordon D, Tibb A. Primary salivary type lung tumor: Mucoepidermoid carcinoma. Respiratory medicine case reports. 9: 18-20, 2013. http://www.ncbi.nlm.nih.gov/pubmed/26029623

Positions Held

  • Instructor (Lung Transplantation, University of Alabama at Birmingham 2016 - 2017)

Awards/Honors

  • Provider of the Month (Tampa General Hospital - 2018)
  • Abstract Scholarship Award (American Thoracic Society - 2015)
  • Research Award (University of Alabama at Birmingham - 2015)
  • Fellow Tract Symposium Travel Award (American Thoracic Society - 2014)
  • Milford Fulop Research Award (Albert Einstein College of Medicine, Bronx, NY - 2013)
  • Best Outgoing Resident Award (Albert Einstein College of Medicine, Bronx, NY - 2013)
  • Leo. M. Davidoff Society Excellence in Teaching Award (Albert Einstein College of Medicine, Bronx, NY - 2012)