Morsani College of Medicine

Current Clinical Research Unit Studies 

The Clinical Research Unit has experience in phase II, III and IV, adult and pediatric clinical trials. The Division’s Clinical Research Unit provides quality research in a variety of clinical areas. Current studies include the following:   

 

Our doctors are looking for children with atopic dermatitis to help test the effectiveness of a new, injectable medication or placebo for the treatment of atopic dermatitis when paired with topical steroid treatment.

  If you are interested in this study, please contact:

Tiffani Kaage, CCRC

813-631-4024 ext. 200

tiffanik@usf.edu

ASTHMA 

If you are interested in participating in an ASTHMA study, please email or call: 

 

Study Coordinator: Catherine Renee Smith, CMA (AAMA), CCRC

 (813) 631-4024 Ext. 207

AllergyCRU@usf.edu

 

PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma)

Our doctors are looking for people diagnosed with asthma to understand how to treat different types of severe asthma, by using precision medicine. 

ALLERGIC FUNGAL RHINOSINUSITIS

Our doctors are evaluating the ability of dupilumab to reduce the need for rescue therapy with systemic corticosteroids (SCS) or surgery of AFRS in patients with AFRS who previously have had surgery for AFRS.

To qualify individuals must be:

  • ≥12 years of age
  • Been diagnosed with Allergic Fungal Rhinosinusitis with Nasal Polyps
  • Have had sino-nasal surgery 
  • Body weight ≥ 30 kg

All study-related care is provided.

Compensation for time and travel may be available for qualified participants.

Principal Investigator: Seong Cho, MD

 

Additional qualification may apply.  If you are interested in this study, please contact:

Tiffani Kaage, Study Coordinator

tiffanik@usf.edu 

813-631-4024 x 200

ALLERGIC RHINITIS

Our doctors are looking for children allergic to dust mites to investigate a sublingual tablet for the treatment of allergic rhinitis.

  • Ages: 5 to 11
  • Weight of ≥ 33 lbs (15 kg)
  • Diagnosis of dust mite allergy for ≥ 12 months with symptoms despite current treatment
  • Duration: 52 weeks
  • Patients who qualify will be compensated for time and travel
  • Principal Investigator: Richard F. Lockey, MD

If you are interested in this study, please contact:

Catherine Renee Smith, CMA (AAMA), CCRC
(813) 631-4024 Ext. 207
catherinesmith@usf.edu

CHRONIC RHINITIS

Our physician, Dr. Seong Cho, is conducting a research study evaluating the efficacy of dupilumab in patients with chronic rhinosinusitis without nasal polyps.  

To qualify you must:

  • Be 18 years or older
  • Have been diagnosed with sinusitis
  • Absence of nasal polyps
  • Suffer from at least two of the following symptoms:

o Nasal blockage/obstruction/congestion

o Nasal discharge (anterior/posterior nasal drip)

o Facial pain/pressure

o Reduction or loss of smell

 

Participation in this research study may last up to 52 weeks.

All study-related care is provided.

Compensation for time and travel is available.

Principal Investigator: Seong Cho, MD

 

If you are interested in this study, please contact:

Tiffani Kaage, Study Coordinator

tiffanik@usf.edu  |  813-631-4024 x 200

 

CHRONIC URTICARIA (Hives)

Our doctors are looking for adolescents and adults with chronic hives despite the use of antihistamines to evaluate a new, investigational injectable medication or placebo for the treatment of this condition.

If you are interested in this study, please contact:

Catherine Renee Smith, CMA (AAMA), CCRC

(813) 631-4024 Ext. 207

catherinesmith@usf.edu

COVID-19

This study is designed with two principal aims:

  1. To estimate the proportions of systemic allergic reactions to the Pfizer-BioNTech COVID-19 Vaccine and the Moderna COVID-19 Vaccine in a HA/MCD population.
  2. If the risk in the HA/MCD is demonstrable, to determine whether the proportions are higher in the HA/MCD compared to a non-atopic population.

Individuals who meet all of the following criteria are eligible for enrollment as study participants:

  • Able to understand and provide informed consent
  • Age 18 to 69 years of age
  • Females of childbearing potential must have a negative pregnancy test prior to the first vaccination and placebo administration

High-Allergy and Mast Cell Disorder (HA/MCD) group:  

Individuals who meet at least one of the following criteria are eligible for enrollment in the HA/MCD group:

  • History of a severe allergic reaction to food(s), allergen immunotherapy, or insect venom(s) with use of epinephrine within the last 5 years
  • History of documented, immediate allergic reactions to 2 or more unrelated drugs within the last 5 years
  • A clinical history of an immediate reaction to a drug or vaccine within the last 5 years
  • History of a physician-diagnosed mast cell disorder    

Non-atopic group:  

Individuals who meet all of the following criteria are eligible for enrollment in the non-atopic group:

  • 1. No history of allergic disorders, including allergic asthma, rhinitis, conjunctivitis, atopic dermatitis, chronic spontaneous urticaria, or angioedema
  • 2. No history of allergic reactions to foods or insect venoms
  • 3. No history of allergic reactions to drugs or vaccines

Principal Investigator: Thomas B. Casale, MD

 Patients who qualify will be compensated for time and travel.

  

If you are interested in this study, please contact:

Catherine Renee Smith, CMA (AAMA), CCRC

(813) 631-4024 Ext. 207

catherinesmith@usf.edu

 

 

HEREDITARY ANGIOEDEMA

Our doctors are looking for people with hereditary angioedema (HAE) being treated with TAKHZYRO (lanadelumab) for a registry study.

  • Ages: 18 and up
  • Diagnosis of Type I or Type II HAE currently being treated with TAKHZYRO (lanadelumab)
  • Duration: 36 months
  • Additional study information available at https://clinicaltrials.gov/ct2/show/NCT03845400
  • Patients who qualify will be compensated for time and travel
  • Principal Investigator: Richard F. Lockey, MD

If you are interested in this study, please contact:

Catherine Renee Smith, CMA (AAMA), CCRC
(813) 631-4024 Ext. 207
catherinesmith@usf.edu

Volunteer

For more information please complete the following form: