PhD Students & Faculty
Jiajia Yang
Contact Info
USF Health Heart Institute, 560 Channelside Dr
Tampa FL 33602
Academic Email: jiajiayang@usf.edu
Interdisciplinary and Emerging Signature Programs
- Cardiovascular Sciences
Research Interests
- We use patient-specific induced pluripotent stem cells (iPSCs) to model hereditary cardiac disease in a dish. Peripheral mononuclear blood cells from patients' blood samples were isolated and reprogrammed into iPSCs to be further differentiated into cardiomyocytes, cardiac fibroblasts and endothelial cells. We perform RNA-seq, electrophysiology and molecular study to discover the precise mechanisms of how genetic variation causes disease particular to the patient. Using iPSC system, we can identify therapeutic targets and test responses of different medications with the ultimate goal of achieving personalized medicine for patients with genetic arrhythmia and cardiomyopathy.