BIOGRAPHICAL SKETCH

Advisory Boards

1997 – 2002                Society for Prevention Research

2002 – Present            National Institute for Early Education Research

2003-Present              National Advisory Council, Suicide Prevention Action Network (SPAN-USA)

A.   Selected publications ( Since 2007 in chronological order).

 Brown CH, Kellam SG, Ialongo N, Poduska J, Ford C. (2007). Prevention of Aggressive Behavior through Middle School using a 

First Grade Classroom-Based Intervention. In Tsuang MT, Lyons MJ, Stone WS (Eds). Recognition and Prevention of Major 

Mental and Substance Abuse Disorders (American Psychopathological Association Series) Arlington, VA: American Psychiatric

Publishing, Inc, pp. 347-370.

Brown CH, Guo J, Singer T, Downes K, and Brinales JM. (in press). Examining the Effects of School-based Drug Prevention 

Programs on Drug Use in Rural Settings: Methodology and Initial Findings.  To appear in J Rural Health.

Kellam SG, Brown CH, Poduska J, et al.  (In press, 2007) Effects of a universal classroom behavior management program in first 

and second grades on young adult behavioral, psychiatric, and social outcomes.  To appear in Drug and Alcohol Dependence.

Gibbons RD, Brown CH, Hur K, Marcus S, Bhaumik DK, and Mann JJ (2007).  The relationship between antidepressants and 

suicide: Results of analysis of the Veterans Health Administration Datasets.  Amer J Psychiatry, 164: 1044-1049.

Brown, C. H, Costigan, T. E., & Kendziora, K. (2008). Data analytic frameworks: Analysis of variance, latent growth and 

hierarchical models.  In Nezu & Nezu (Eds) Evidence-Based Outcome Research: A Practical Guide to Conducting 

Randomized Clinical Trials for Psychosocial Interventions (pp. 285-313). London: Oxford University Press, 285-313.

Gibbons RD, Brown CH, Hur K, Marcus S, Mann JJ, Erkens J,  and Herings R (2007).  Early Evidence on the Effects of the 

Regulators’ Suicidality Warnings on SSRI Prescription and Suicide in Children and Adolescents. 

Amer J Psychiatry, Amer J Psychiatry, 164: 1356-1363.

Brown CH, Wyman PA, Brinales JM, and Gibbons RD  (in press).  The role of randomized trials in testing interventions for 

the prevention of youth suicide.  To appear in International Journal of Psychiatry.

Dagne G. A., Brown C. H., and Howe G.W.  (in press 2007) Hierarchical modeling of sequential behavioral data: Log-linear 

extensions to study complex association patterns in mediation models. To appear in Psych Methods.

Poduska J, Kellam SG, Wang W, Brown CH, Ialongo N, Toyinbo P, Impact of the Good Behavior Game, a Universal 

Classroom–Based Behavior Intervention, on Young Adult Service Use for Problems with Emotions, Behavior, or Drugs or 

Alcohol.  To appear in Drug and Alcohol Dependence.

Peña JB, Wyman PA, and Brown CH.  Immigration generation status and suicide attempts among Latino adolescents in the 

United States.  Accepted for publication (with revisions) Prevention Science.

MacKinnon, D. P., Lockwood, C. M., Brown, C. H. & Hoffman, J. M.  (2007). The intermediate endpoint effect in logistic and probit 

regression.  Clinical Trials, 4, 499-513.

Gibbons RD, Brown CH, Mann JJ. (2007). SSRI prescribing rates and adolescent suicide: Is the black box hurting or helping?  

Psychiatric Times, 24.  Downloadable from http://www.psychiatrictimes.com/showArticle.jhtml?articleID=202101003&C.

Kellam SG, Brown CH, Poduska J, Ialongo N, Petras H, Wang W, Toyinbo P, Wilcox HC, Ford C, Windham A. Summary of 

Cohort 2 Analyses - Supplement to “Effects of a Universal Classroom Behavior Management Program in First and Second Grades 

on Young Adult Behavioral, Psychiatric, and Social Outcomes”. Drug and Alcohol Dependence Special Issue on 

Prevention (in press, 2007).

Petras H, Kellam SG, Brown CH, Muthén B, Ialongo N, Poduska J (in press, 2007).  Developmental Courses Leading to Antisocial 

Personality Disorder and Violent and Criminal Behavior: Effects by Young Adulthood of a Universal Preventive Intervention in First- and 

Second-Grade Classrooms.  To appear in Drug and Alcohol Dependence Special Issue on Prevention.

Wilcox HC, Kellam SG, Brown CH, Poduska J Ialongo NS, Wang W, and Anthony JC (in press, 2007).  The Impact of two Universal 

Randomized First and Second Grade Classroom-Based Interventions on Young Adult Suicide-Related Behaviors. To appear in Drug 

and Alcohol Dependence Special Issue on Prevention.

Wyman PA, Brown CH, Inman J, Cross W, Schmeelk-Cone K, Guo J, Peña J (accepted for publication).  Randomized Trial of a Gatekeeper 

Training Program for Suicide Prevention:  Impact on School Staff after One Year.  To appear in J Consulting and Clinical Psycholology.

Jo B, Asparouhov T, Muthén BO, Ialongo N, and Brown CH (accepted for publication.) Cluster randomized trials with treatment noncompliance.  

To appear in Psych Methods.

Brown CH, Wang W, Kellam SG, Muthén BO et al., (in press 2007).  Methods for Testing Theory and Evaluating Impact in Randomized Field 

Trials: Intent-to-Treat Analyses for Integrating the Perspectives of Person, Place, and Time.  To appear in J Drug and Alcohol Dependence 

Special Issue on Prevention.

B.   Current and Recent Research Support.

Methodology for Mental Health and Drug Abuse Prevention and Early Intervention.  R01MH40859. Funded by NIMH and NIDA.  P.I. C Hendricks Brown (2005 – 2009).  This is a competing continuation of the primary R01 that has supported the Prevention Science and Methodology Group (Designs and Analyses for Mental Health Preventive Trials MH40859).  These aims extend the current work by developing an integrated set of new statistical models, Multilevel Growth Mixture Models, that incorporate person-level, time, and context in the same methodology.  We also present new statistical designs for randomized field trials and incorporate nonlinear “additive” models.  A second aim focuses on designs and analyses for low baserate disorders, including suicide, psychosis, and drug abuse/dependence.  The third aim will focus on the designs and analyses specifically appropriate for implementing interventions with communities.  We will develop new designs for implementation trials, including trials outside a trial and trials after a trial.

Prevention Services for Schools for Early Drug Abuse Risk. Funded by NIDA 1R01DA015409, P.I. Sheppard Kellam, Co-PI, C. Hendricks Brown, Jeanne Poduska, John Reid (Current Funding 2002 – 2007).  This involves a third generation preventive field trial of a classroom-based intervention aimed at early risk factors for substance abuse.  Both first-grade children and their teachers are randomized to intervention or standard classrooms in first grade.  The intervention aims at enhancing reading, through improved curriculum, training, and coaching, at aggressive/disruptive behavior through the Good Behavior Game and other classroom management techniques, and through a parent-teacher partnership.  There are three phases to this study, an effectiveness trial for the first cohort, which is followed through third grade, a sustainability trial examining impact in second and third cohorts, and a scalability trial examining how impact is affected when the intervention is expanded to whole schools.

RCT of Gatekeeper Training for Suicide Prevention.  Funded by NIMH. R34MH071189-01 PI Peter Wyman, Co-PI C. Hendricks Brown (2004 – 2007).  This R34 application to the National Institute of Mental Health is for testing with a randomized school-based trial a model of gatekeeper training of all staff in 32 middle and high schools in a school district in Georgia.  The QPR training program is provided in a wait-listed design to all schools.  Working closely with the school’s Prevention Intervention Center, we will evaluate whether more children with suicidal ideation and behaviors are identified, get professionally assessed and enter treatment.  Levels of suicidal ideation in 8^th and 10^th grades are also examined.

Developing Center On Public Health And Population Interventions For The Prevention Of Suicide.  Funded by NIMH.  P.I., Eric Caine, Co-PI and Methodology Core Co-Director, C Hendricks Brown (2004 – 2009).  This application represents a collective vision for public health and population-oriented approaches to preventing suicide and attempted suicide, and the morbidity arising from myriad associated risk factors.  The PHP-Center develops new theories of prevention, using novel research designs and measures, and extend the application of new theoretical and analytic approaches to suicide prevention and intervention research, and, carry out high quality investigations that move forward efforts to reduce the mortality and morbidity of suicide, attempted suicide, and related antecedent conditions. 

ASU Prevention Research Center for Families in Stress.  Funded by NIMH.  P30MH068685, PI Irwin Sandler, Co-I, C Hendricks Brown. (2005-2009).

The Center focuses on preventive interventions for children who are at risk for developing mental health problems because of exposure to high stress situations; parental divorce, parental death and inner city, Mexican American children in transition to high school. The overall objective of the application is to make the transition from University based studies of the efficacy of preventive interventions to the effectiveness of programs as implemented in community agencies. Concepts and methods from service marketing, quality management and educational design are used to redesign the programs so that they can be readily implemented in community agencies. The Research Methods Core develops collaborative workgroups of methodologists and substantive researchers to focus on five methodological issues: measurement, variability in outcomes, implementation and compliance with interventions, multilevel data, and economic analysis.

Community Development Teams to Scale-Up MTFC in California  Funded by NIMH. R01MH076158, PI Patricia Chamberlain, Co-PI C Hendricks Brown(2006 – 2010).  In this application, we propose to test the effectiveness of the Community Development Team (CDT), a theory-driven model to promote the adoption, implementation, and sustainability of one such intervention (Multidimensional Treatment Foster Care; MTFC) in California counties that are not already using MTFC. To examine the effectiveness of the CDT intervention, counties will be randomly assigned to the CDT plus Standard Implementation of MTFC (CDT) condition, or to the Standard Implementation of MTFC only (SI) condition. The CDT intervention model was developed in an effort to engage and support evidence-based programming throughout the state. We will test whether a set of fixed contextual factors moderate the hypothesized intervention effect. Additionally, we will examine whether changes in a set of dynamic contextual factors mediate the association between random assignment and the intervention effects.