Center for Environmental/Occupational Risk Analysis & Management

Research & Publications

CEORAM is committed to research and scientific inquiry related to issues of environmental and occupational health. Whether you are a potential student, a potential research collaborator, or in need of research consultation, we invite you to review current and past research initiatives conducted by the Center.

Current Research Initiatives

Pharmacological Modulation of Chemical and Drug Induced Nephro- and Hepatotoxicity

This ongoing project investigates the action of Poly (ADP-ribose) polymerase (PARP) inhibitors in blocking or attenuating drug and chemical-induced hepatotoxicity in both in vivo and in vitro models. The goals of this project are to evaluate the mechanism of PARP activation and the resulting cellular toxicity, to evaluate the extent to which various nephro- and hepatotoxicants induce toxicity by the mechanism of PARP activation, and to investigate the efficacy of PARP inhibitors in blocking or attenuating the toxic effects of PARP induction. This research has received funding from the United States Department of Defense.

Principal Investigator: Dr. Raymond D. Harbison
Co-Investigators: Dr. Marie Bourgeois, Dr. Giffe Johnson

Pesticide Biomonitoring in Florida Agricultural Workers

This project aims to collect pilot data on the various classes of pesticides found in biological samples provided by Florida farm workers following pesticide application. The goals of this project include determining the types and concentrations of pesticides in the serum of applicators shortly after pesticide application; assessing the use of personal protective equipment among these applicators; and strengthening the relationship between the project team and the Farmworker Association of Florida. The outcomes of this project will help evaluate the safety of agricultural workers working with pesticides and help determine the needs of future training and research. This work is being funded through a grant from the University of Kentucky Southeast Center for Agricultural Health and Injury Prevention and the NIOSH Sunshine ERC here at USF.

Principal Investigator: Dr. Giffe T. Johnson

Recent Publications

Presentations

  • CEORAM is committed to presenting the research of our students and faculty at regional, national, and international scientific conventions. For recent presentations, a poster is available for you to review by clicking the link.
  • Ann Jurkowski, Charles L. Blake, Giffe T. Johnson, and Raymond D. Harbison. Exposure Associated with Power Stripping of Asbestos Containing Insulation from Electrical Cable. Society of Toxicology, 2013 San Antonio
  • SC Harbison, GT Johnson, JD McCluskey, P Xu, J White, S Mohammed, J Wolfson, RD Harbison. Pulmonary Function Testing in Emergency Responders. Society of Toxicology, 2013 San Antonio
  • Robin DeHate, Brian Skelly, Ushang P Desai, Giffe T Johnson, Raymond D Harbison. Managing Public Health Risks Using Air Monitoring at a Former Manufactured Gas Plant (MGP) Site. Society of Toxicology, 2013. San Antonio
  • Blake, C.L., M. Stubbs, G. T. Johnson, and R. D. Harbison. Evaluation of asbestos exposure associated with asbestos containing gauze pads. Society of Toxicology, 2012 San Francisco.
  • LeBeau, A. G. Johnson, J. McCluskey, and R. Harbison. Evaluation of urinary pesticide biomarkers among children and adolescents. Society of Toxicology, 2012 San Francisco.
  • Harbison, S.C., Johnson G.T., J. McCluskey, P. Xu, J. White, S. Mohammed, J. Wolfson, and R.D. Harbison. Pulmonary function testing in utility workers. Society of Toxicology, 2012 San Francisco.
  • Johnson, G.T., J. White, C. Younger, and R.D. Harbison. Characterization of Veterans Poisonings in the State of Florida. Society of Toxicology, 2012 San Francisco.
  • Johnson GT, Harbison SC, McCluskey JD, Xu P, Thomas L, Goldman S, and Harbison RD. Pulmonary function testing in boat manufacturing workers. Society of Toxicology, 2011 Washington DC.
  • DeHate RB, Skelly B, Johnson GT, and Harbison RD. Assessment of public health risks associated with naphthalene entering residences and commercial space from vapor intrusion at MGP sites. Society of Toxicology, 2011 Washington DC.
  • Blake CL, Harbison SC, Johnson GT, and Harbison RD. Asbestos exposure associated with fire sleeve materials. Society of Toxicology, 2011 Washington DC.
  • LeBeau A, Johnson G, McCluskey J, and Harbison R. Evaluation of Urinary Pesticide Biomarkers Among Residents of the United States. Society of Toxicology, 2010 Salt Lake City
  • J. McCluskey, S.C. Harbison, D. Sava, and R.D. Harbison Hepatoprotective Effects of Selected Water Soluble PARP1 Inhibitors.pdf Society of Toxicology, 2009. Baltimore MD
  • R. DeHate, G. Johnson, R. Harbison. Evaluation of the Public Health Risks Associated with former Manufactured Gas Plants (MGP). Society of Toxicology, 2009. Baltimore MD
  • Malek Khlifi, M.D., Leslie Zun, M.D., Giffe Johnson, Ph.D., Raymond D. Harbison, Ph.D. Etiological Characterization of Emergency Department Acute Poisoning.pdf Society of Toxicology, 2009. Baltimore MD
  • G. Johnson, S.C. Harbison, J. McCluskey, and R. Harbison Characterization of Cancer Risk Associated with Measured Airborne Benzene Levels in the State of Florida.pdf Society of Toxicology March, 2008 Seattle WA
  • Sava, V., R. Harbison, J. Sanchez-Ramos. Effects of diethyl maleate preconditioning on the expression of DNA repair genes in midbrain elicited by Ochratoxin-A. Society of Toxicology, 2008.
  • Charles L. Blake, G. Scott Dotson, Giffe Johnson, Raymond D. Harbison Exposure to Asbestos within the Automotive Repair Industry Beyond Brake Components.pdf. Society of Toxicology March, 2007 Charlotte NC
  • Grivas, P.C., K.W. Hall, C. Muro-Cacho, and R.D. Harbison: Aminophylline-induced inhibition of carbon-tetrachloride-induced hepatotoxicity. Society of Toxicology, 2006
  • BLAKE, C., C. S. DOTSON, AND R. D. Harbison: Assessment of asbestos exposure among automotive mechanics servicing and handling asbestos containing gaskets.pdf. Society of Toxicology, 2006.
  • Hall, K., P. Grivas, C. Muro-Cacho., and R. D. Harbison. 6(5H) Phenanthridinone alteration of bromobenzene-induced hepatotoxicity. Society of Toxicology, 2006.
  • Lumpkin, M.H., V. Runnion, R. Liackfield, S. Paul, and R.D. Harbison. Simulation and assessment of occupational exposures to isocyanates and VOCs during application of a urethane product suite under worst-case conditions. Society of Toxicology, 2005.
  • Silver, D. and R.D. Harbison. Occupational exposure to ultrafine particles and polycyclic aromatic hydrocarbons from candle emissions. Society of Toxicology, 2005.
  • Hall, K., C. Muro-Cacho, and R.D. Harbison. Nicotinimide alteration of bromobenzene-induced hepatotoxicity. Society of Toxicology, 2005.
  • Banasik, M., T. Stedeford, C. Muro-Cacho, and R. Harbison. Overactivation of poly (ADP-ribose) polymerase-1 accompanies carbon tetrachloride-induced centrilobular necrosis. Society of Toxicology 78:310, 2004.
  • Harbison, R., M. Banasik, T. Stedeford, N. Matoh, S. Tanaka, M. Takehashi, and K. Ueda. Neuroprotective effects of CYP2D6 overexpression in differentiated PC12 Cells. Society of Toxicology 78:346, 2004.
  • SILVER, D AND R. D. HARBISON. Occupational Exposure to Ultrafine Particles and Polycylic Aromatic Hydrocarbons from Candle Emissions. American Association for Aerosol Research (AAAR) October 04-08, 2004.
  • Banasik, M., S. P. Su, D. Mosquera, T. Stedeford and R. D. Harbison: Phenanthridinone attenuates the hepatotoxicity of carbon tetrachloride. Society of Toxicology 72:360, 2003.
  • Francois, M.R., P. Grivas, and R.D. Harbison: Predicting risk of hospital admissions using an air pollution model. Society of Toxicology 72:186, 2003.
  • Banasik, M., D. Vanorden, C, Blake, and R.D. Harbison: Automobile brake maintenance and airborne chrysotile fiber exposure. Society of Toxicology 72:183-184, 2003.
  • Mosquera, D.J., T. Stedeford, M. Banasik, C. Muro-Cacho, and R.D. Harbison: Adrenergic modulation of ethylene dibromide-induced toxicity. Society of Toxicology 72:347, 2003.
  • Scharf, J. M. Martinez, T. Stedeford, G. Hahn, and R. Harbison. Assessment of the skin absorption of malathion. Society of Toxicology 72:390, 2003.
  • Sava, V., D. Mosquera, S. Song, K. Calero, R. Harbison, F. Carozo-Pelaez, and J. SANCHEZ-RAMOS. Distribution of oxidative DNA damage and oxyguanosine glycosylase activities across brain regions of mice injected with a single dose of rubratoxin-B. Neuroscience, 2003.
  • DeHate, R, K. Waggoner, S. Oluwole, R. Francois, and R.D. Harbison: A methodology for a public health biomonitoring program. American Public Health Association, 2003.
  • Tabone, R.D. and R.D. Harbison. The influence of risk communication on risk perceptions. Society of Toxicology 66:487, 2002.
  • Francois, M.R., J. Studnicki, and R.D. Harbison. Defining a methodology to assess the environmental health status of a community. Society of Toxicology 66:488, 2002.
  • Stedeford, T., F. Cardozo-Palaez, G.E. Luzardo, D. Mosquera, M. Banasik, and R.D. Harbison. Strain-specific differences in superoxide dismutase and 8-oxoguanosine DNA-glycosylase capacity of male c57BL/J, BALB/C, and ICR mice. Society of Toxicology 66:769, 2002.
  • Thrasher, C., R. Lee, R, DeHate, and R.D. Harbison. OUTBREAK: A model for identifying bioterrorism attacks. Association of Schools of Public Health, Environmental Health Conference, September, 2002.
  • Blake, C.L., D.J. Silver, and R.D. Harbison. Assessment of the public health risks associated with candle emissions. Society of Toxicology 60: 198, 2001.