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Wayne Cruse, MD

Professor, College Of Medicine Surgery

Juan Bolivar Endowed Chair in Surgical Oncology, Surgery

Senior Member, Cutaneous Oncology Program

Professor, Department Of Oncologic Sciences

Juan Bolivar Endowed Chair in Surgical Oncology, Surgery, University of South Florida

Senior Member, Cutaneous Oncology Program, Moffitt Cancer Center & Research Institute

Contact Info Tampa General Hospital
1 Tampa General Circle - G214
Tampa, FL 33606

Academic Email: wcruse@health.usf.edu

Academic Phone: (813) 844-8546

View My C.V.


  • MD, Medicine, University Of Louisville, 1972

Research Interests

  • melanoma, Merkel cell carcinoma, basal cell cancer, squamous cell cancer, angiosarcoma, sentinel lymph node surgery, cancer reconstruction, reconstruction after micrographic surgey, burn care, wound care, Moffitt Cancer Center and Research Institute,. wound care


  • American Association of Plastic Surgeons (member, 1995 - Present)
  • Society of Surgical Oncology (member, 1995 - Present)
  • American Society of Plastic Surgeons (member, 1981 - Present)
  • American Burn Association (member, 1979 - Present)

Recent Publications

  • Yacoub A, Soni KK, Mojica L, Mai J, Morano J, Cruse CW, Sandin RL, Nanjappa S, Bohra C, Gajanan G, Greene JN. Primary Gangrenous Cutaneous Mold Infections in a Patient With Cancer and Neutropenia. Cancer control : journal of the Moffitt Cancer Center. 23(3) : 265-71, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27556666
  • Strom T, Carr M, Zager JS, Naghavi A, Smith FO, Cruse CW, Messina JL, Russell J, Rao NG, Fulp W, Kim S, Torres-Roca JF, Padhya TA, Sondak VK, Trotti AM, Harrison LB, Caudell JJ. Radiation Therapy is Associated with Improved Outcomes in Merkel Cell Carcinoma. Annals of surgical oncology. 23(11) : 3572-8, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27251134
  • Franz O, Smith MBBS1; Binglin Yue MS2; Suroosh S, Marzban MD3; Brooke L, Walls MD4; Michael Carr MS3; Ryan S, Jackson MD5; Christopher A, Puleo PA-C1; Tapan Padhya MD5; C, Wayne Cruse MD1; Ricardo J, Gonzalez MD1; Amod A, Sarnaik MD1; Michael J, Schell PhD2; Ronald C, DeConti MD1; Jane L, Messina MD16; Vernon K, Sondak MD1; Jonathan S, Zager MD1, . Both Tumor Depth and Diameter Are Predictive of Sentinel Lymph Node Status and Survival in Merkel Cell Carcinoma. Cancer.. : ; www.wileyonlinelibrary.com, 2015.
  • Yamamoto M Fisher KH Wong JY Koscso JM Konstantinovic MA Govsyeyev N Messina JL Sarnaik AA Cruse CW Gonzalez RJ Sondak VK Zager JS, Sentinel Lymph Node Biopsy is Indicated for Patients with Thick Clinically Lymph-Node Negative Melanoma. Cancer.. 121(10) : 1628-36, 2015.
  • Doepker MP Yamamoto M Fisher KJ Nethers KW Harb JN Applebaum MA Patel N Cruse WC Gonzalez RJ Sarnaik AA Sondak VK Zager JS. Is a Wider Margin (2 cm vs 1cm) for a 1.0 -2.0 mm Thick Melanoma Necessary? World Congress of Lymphology Annual Meeting.. , 2015.
  • Ching JA Curtis HL Braue JA Kudchadkar RR Mendoza TI Messina JL Cruse CW Smith DJ Jr Harrington MA. The Impact of Neoadjuvant Hedgehog Inhibitor Therapy on the Surgical Treatment of Extensive Basal Cell Carcinoma. Ann Plast Surg.. 74(4) : S193-7, 2015.
  • Han D Han G Zhao X Rao NG Messina JL Marzban SS Sarnaik AA Cruse CW Sondak VK Zager JS. Clinicopathologic Predictors of Survival in Patients with Desmoplastic Melanoma. PloS One.. 10(3) : e0119716. Doi: 10.1371/journal.pone.0119716. eCollection 2015., 2015.
  • Doepker MP Patel N Yamamoto M Djulbegovic M J Montilla-Soler Eikman E Gonzalez RJ Cruse CW Sarnaik AA Sondak VK Zager JS, . Single photon emission computed tomography (SPECT) compared with conventional planar lymphoscintigraphy (LS) for preoperative sentinel node localization in cutaneous malignancies. American College of Surgeons – Surgical Forum.. , 2015.
  • Strom T Caudell JJ Han D Zager JS Yu D Cruse CW Marzban SS Messina JL Trotti AM Sondak VK Rao NG, . Radiotherapy Influences Local Control in Patients with Desmoplastic Melanoma. Cancer.. 120(9) : 1369-78, 2014.
  • Smith DJ Karlnoski RA Patel A Cruse CW Brown KS Robson MC. The Treatment of Partial-Thickness Bums with a Hydroconductive Wound Dressing: Clinical and Mechanistic Effects. Surnical Science. 4: 268-72, 2013.
  • Troy J, Karlnoski R, Downes K, Brown KS, Cruse CW, Smith DJ, Payne WG. The Use of EZ Derm® in Partial-Thickness Burns: An Institutional Review of 157 Patients. Eplasty. 13: e14, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23573334
  • Kartnoski R Cruse CW Brown KS Sprenker CJ Smith DJ. Use of Drawtex In Thennal Injuries. Wounds.(Supplement). 32(9) : 17-18, 2012.
  • Deneve JL, Messina JL, Marzban SS, Gonzalez RJ, Walls BM, Fisher KJ, Chen YA, Cruse CW, Sondak VK, Zager JS. Merkel cell carcinoma of unknown primary origin. Annals of Surgical Oncology. 19(7) : 2360-6, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22271206
  • Han D, Yu D, Zhao X, Marzban SS, Messina JL, Gonzalez RJ, Cruse CW, Sarnaik AA, Puleo C, Sondak VK, Zager JS. Sentinel node biopsy is indicated for thin melanomas ≥0.76 mm. Annals of Surgical Oncology. 19(11) : 3335-42, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22766986
  • Schleich AR, Schweiger H, Becsey A, Cruse CW. Survival after severe intrathoracic electrical injury. Burns : Journal of the International Society for Burn Injuries. 36(5) : e61-4, 2010. http://www.ncbi.nlm.nih.gov/pubmed/19819635
  • Pu LL, Wells KE, Cruse CW, Shons AR, Reintgen DS. Prevalence of additional positive lymph nodes in complete lymphadenectomy specimens after positive sentinel lymphadenectomy findings for early-stage melanoma of the head and neck. Plastic and reconstructive surgery. 112(1) : 43-9, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12832875
  • Pu LL, Cruse CW, Wells KE, Cantor A, Glass LF, Messina JL, Reintgen DS. Lymphatic mapping and sentinel lymph node biopsy in patients with melanoma of the lower extremity. Plastic and reconstructive surgery. 104(4) : 964-9, 1999. http://www.ncbi.nlm.nih.gov/pubmed/10654734
  • Reintgen D, Albertini J, Milliotes G, Marshburn J, Cruse CW, Rapaport D, Berman C, Glass F, Fensske N, Einstein AB, Lyman G. Investment in new technology research can save future health care dollars. The Journal of the Florida Medical Association. 84(3) : 175-81, 1997. http://www.ncbi.nlm.nih.gov/pubmed/9143169
  • Kamath D, Rapaport D, DeConti R, Cruse CW, Wells K, Glass F, Messina J, Fenske N, Brobeil A, Berman C, Puleo C, Reintgen D. Redefining cutaneous lymphatic flow: the necessity of preoperative lymphoscintigraphy in the management of malignant melanoma. The Journal of the Florida Medical Association. 84(3) : 182-7, 1997. http://www.ncbi.nlm.nih.gov/pubmed/9143170
  • Wells KE, Rapaport DP, Cruse CW, Payne W, Albertini J, Berman C, Lyman GH, Reintgen DS. Sentinel lymph node biopsy in melanoma of the head and neck. Plastic and reconstructive surgery. 100(3) : 591-4, 1997. http://www.ncbi.nlm.nih.gov/pubmed/9283554
  • Glass LF, Messina JL, Cruse W, Wells K, Rapaport D, Miliotes G, Berman C, Reintgen D, Fenske NA. The use of intraoperative radiolymphoscintigraphy for sentinel node biopsy in patients with malignant melanoma. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 22(8) : 715-20, 1996. http://www.ncbi.nlm.nih.gov/pubmed/8780765
  • Glass LF, Fenske NA, Messina JL, Cruse CW, Rapaport DP, Berman C, Puleo CA, Heller R, Miliotes G, Albertini J. The role of selective lymphadenectomy in the management of patients with malignant melanoma. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 21(11) : 979-83, 1995. http://www.ncbi.nlm.nih.gov/pubmed/7582838
  • Wang X, Heller R, VanVoorhis N, Cruse CW, Glass F, Fenske N, Berman C, Leo-Messina J, Rappaport D, Wells K. Detection of submicroscopic lymph node metastases with polymerase chain reaction in patients with malignant melanoma. Annals of surgery. 220(6) : 768-74, 1994. http://www.ncbi.nlm.nih.gov/pubmed/7986144
  • Wells KE, Cruse CW, Baker JL, Daniels SM, Stern RA, Newman C, Seleznick MJ, Vasey FB, Brozena S, Albers SE. The health status of women following cosmetic surgery. Plastic and reconstructive surgery. 93(5) : 907-12, 1994. http://www.ncbi.nlm.nih.gov/pubmed/8134482
  • Wells KE, Cruse CW, Daniels S, Berman C, Norman J, Reintgen DS. The use of lymphoscintigraphy in melanoma of the head and neck. Plastic and reconstructive surgery. 93(4) : 757-61, 1994. http://www.ncbi.nlm.nih.gov/pubmed/8134434
  • Reintgen D, Cruse CW, Wells K, Berman C, Fenske N, Glass F, Schroer K, Heller R, Ross M, Lyman G. The orderly progression of melanoma nodal metastases. Annals of surgery. 220(6) : 759-67, 1994. http://www.ncbi.nlm.nih.gov/pubmed/7986143
  • Cruse CW, Radocha RF. Squamous cell carcinoma of the lip. Plastic and reconstructive surgery. 80(6) : 787-91, 1987. http://www.ncbi.nlm.nih.gov/pubmed/3685181
  • Simpson LA, Cruse CW. Gasoline immersion injury. Plastic and reconstructive surgery. 67(1) : 54-7, 1981. http://www.ncbi.nlm.nih.gov/pubmed/7443860