Faculty

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MichelMurr

Michel Murr, MD

Professor, College Of Medicine Molecular Pharmacology & Physiology

Professor, College Of Medicine Surgery

Chief of Surgery, Surgery

Director of Bariatric Surgery, Department Of Surgery

Chief of Surgery, Surgery, Tampa General Hospital

Director of Bariatric Surgery, Department of Surgery, Tampa General Hospital

Contact Info 5 TGH Circle
HMT Suite 410
Tampa, FL 33606

Academic Email: mmurr@health.usf.edu

Academic Phone: (813) 847-4730

Education

  • MD, American University Of Beirut, 1982

Interdisciplinary and Emerging Signature Programs

  • Other

Research Interests

  • My clinical research covers a wide area of outcomes after bariatric surgery and emerging technology for the treatment of diabetes and obesity
  • My lab research efforts are focused on an animal model of obesity and the molecular mechanism of diabetes and obesity; we are seeking answers that will lead to drug discovery and thereby translate into clinical protocol and cutting edge medicine

Recent Publications

  • Dayicioglu D Tugertimur B Munzenmaier K Khan M Smith P Murr MM Kumar A Khakpour N. Outcomes of Breast Reconstruction after Mastectomy Using and Massive Weight Loss. Ann Plast Surg. 76: S286-9, 2016.
  • Alvey N Ching YH Karlonski RA Dalvi RA Murr MM Mangar D Caporessi EM. Systemic intra-operative lidocaine infusion for post-op pain in obese patients. A randomized placebo controlled study. Case Studies in Surg. 2(4) : 10-16, 2016.
  • Patel RS Carter G El Bassit G Patel AA Cooper DR Murr MM Patel NA. ADSC from lean and obese humans show depot specific differences in stem cell markers, exosome contents and senescence: role of PKCδ in adipose stem cell niche. Stem Cell Investig.. 31(3) : 2, 2016.
  • Taitano AA, Markow M, Finan JE, Wheeler DE, Gonzalvo JP, Murr MM. Bariatric surgery improves histological features of nonalcoholic fatty liver disease and liver fibrosis. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 19(3) : 429-36; discussion 436-7, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25537957
  • Morris A Patel R Carter G Murr MM Cooper D Patel N. LncRNA NEAT1 secreted by adipose derived stems cells from obese subjects regulates alternative splicing of PKCδVIII in ovarian cancer cells. Int J Molecular Science. , 2015.
  • Murr MM. Is Glucagon-like peptide-1 for real? Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 10(5) : 786, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24935178
  • Eid JJ, Radecke JM, Murr MM. Gastrointestinal bleeding from the excluded stomach: a proposed algorithmic approach to management. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 11(1) : e11-4, 2014. http://www.ncbi.nlm.nih.gov/pubmed/25449066
  • Watson JE, Patel NA, Carter G, Moor A, Patel R, Ghansah T, Mathur A, Murr MM, Bickford P, Gould LJ, Cooper DR. Comparison of Markers and Functional Attributes of Human Adipose-Derived Stem Cells and Dedifferentiated Adipocyte Cells from Subcutaneous Fat of an Obese Diabetic Donor. Advances in wound care. 3(3) : 219-228, 2014. http://www.ncbi.nlm.nih.gov/pubmed/24669358
  • Carter G, Patel R, Apostolatos A, Murr M, Cooper DR, Patel NA. Protein kinase C delta (PKCδ) splice variant modulates senescence via hTERT in adipose-derived stem cells. Stem cell investigation. 1: 3, 2014. http://www.ncbi.nlm.nih.gov/pubmed/27358850
  • Peng Y, Murr MM. Roux-en-Y gastric bypass improves hepatic mitochondrial function in obese rats. Surgery for Obesity and Related Diseases : Official journal of the American Society for Bariatric Surgery. 9(3) : 429-35, 2013. http://www.ncbi.nlm.nih.gov/pubmed/21890425
  • Sahebzamani FM, Berarducci A, Murr MM. Malabsorption anemia and iron supplement induced constipation in post-Roux-en-Y gastric bypass (RYGB) patients. Journal of the American Association of Nurse Practitioners. 25(12) : 634-40, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24170670
  • Carter G, Apostolatos A, Patel R, Mathur A, Cooper D, Murr M, Patel NA. Dysregulated Alternative Splicing Pattern of PKCδ during Differentiation of Human Preadipocytes Represents Distinct Differences between Lean and Obese Adipocytes. ISRN obesity. 2013: 161345, 2013. http://www.ncbi.nlm.nih.gov/pubmed/24533217
  • Peng Y, Rideout D, Rakita S, Lee J, Murr M. Diet-induced obesity associated with steatosis, oxidative stress, and inflammation in liver. Surgery for Obesity and Related Diseases : Official journal of the American Society for Bariatric Surgery. 8(1) : 73-81, 2012. http://www.ncbi.nlm.nih.gov/pubmed/21978752
  • Peng Y, Sigua CA, Murr MM. Protein kinase C-zeta mediates apoptosis of mouse Kupffer cells via ERK-1/2: a novel mechanism. Surgery. 149(1) : 135-42, 2011. http://www.ncbi.nlm.nih.gov/pubmed/20570304
  • Fakhry TK, Murr MM. Role of endoscopy in evaluation and management of persistent gastrojejunostomy leaks after Roux-en-Y gastric bypass. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 7(2) : 232-4, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21130047
  • Nguyen NT, Dakin G, Needleman B, Pomp A, Mikami D, Provost DA, Scott DJ, Jones DB, Gallagher S, Gagner M, Murr M. Effect of staple height on gastrojejunostomy during laparoscopic gastric bypass: a multicenter prospective randomized trial. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 6(5) : 477-82, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20870179
  • Rafiei A Ajami H Fakhry T Murr MM. Overview of emerging concepts in metabolic surgery. Perm J. 3: 57-62, 2010.
  • Rideout D Peng Y Rakita S Desai K You M Murr MM. RYGB Alters TNF-alpha but not Adiponectin Signaling in the Immediate Postoperative Period in Obese Rats. Surg Obes Relat Dis. 6: 676-80, 2010.
  • Murr M, Rafiei A, Ajami H, Fakhry TK. Overview of emerging concepts in metabolic surgery. The Permanente journal. 14(3) : 57-62, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20844706
  • Gallagher SF, Haines KL, Osterlund L, Murr M, Downs JB. Life-threatening postoperative hypoventilation after bariatric surgery. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 6(1) : 102-4, 2010. http://www.ncbi.nlm.nih.gov/pubmed/19560977
  • Peng Y, Rideout DA, Rakita SS, Gower WR, You M, Murr MM. Does LKB1 mediate activation of hepatic AMP-protein kinase (AMPK) and sirtuin1 (SIRT1) after Roux-en-Y gastric bypass in obese rats? Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 14(2) : 221-8, 2010. http://www.ncbi.nlm.nih.gov/pubmed/19937189
  • Kuruba R, Jawad M, Karl RC, Murr MM. Technique of resection of esophageal adenocarcinoma after Roux-en-Y gastric bypass and literature review of esophagogastric tumors after bariatric procedures. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 5(5) : 576-81, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19640802
  • Ajami H, Bakhos W, Rafiei A, Dishjekenian M, Murr MM. Initial experience with two-incision laparoscopic adjustable gastric banding. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 5(6) : 666-9, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19640805
  • Shen Z, Ajmo JM, Rogers CQ, Liang X, Le L, Murr MM, Peng Y, You M. Role of SIRT1 in regulation of LPS- or two ethanol metabolites-induced TNF-alpha production in cultured macrophage cell lines. American journal of physiology. Gastrointestinal and liver physiology. 296(5) : G1047-53, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19299582
  • Berarducci A, Haines K, Murr MM. Incidence of bone loss, falls, and fractures after Roux-en-Y gastric bypass for morbid obesity. Applied nursing research : ANR. 22(1) : 35-41, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19171293
  • Peng Y, Sigua CA, Rideout D, Murr MM. Deletion of toll-like receptor-4 downregulates protein kinase C-zeta and attenuates liver injury in experimental pancreatitis. Surgery. 143(5) : 679-85, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18436016
  • Kaly P, Orellana S, Torrella T, Takagishi C, Saff-Koche L, Murr MM. Unrealistic weight loss expectations in candidates for bariatric surgery. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 4(1) : 6-10, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18201668

Awards/Honors

  • USF Research Day: Outstanding Resident Research (University of South Florida - 2009)
  • USF Research Day: Superior Presentation Award (Univeristy of South Florida - 2008)
  • USF Research Day: Superior Presentation Award (University of South Florida - 2006)
  • USF Research Day: Superior Presentation Award (University of South Florida - 2006)
  • USF Research Day: Superior Presentation Award (University of South Florida - 2005)
  • USF Research Day: Superior Presentation Award (University of South Florida - 2003)
  • USF Research Day: Superior Presentation Award (University of South Florida - 2002)
  • Traveler Award (Japan Surgical Society - 2001)
  • University of South Florida (OCO 2001 Award - 2001)
  • Research and Creative Scholarship Award (University of South Florida - 2001)
  • SSAT Career Development Award Grant (SSAT - 2001)
  • Resident Research Award (Iowa Academy of Surgery - 1992)
  • Resident Research Award (Iowa Academy of Surgery - 1991)