Current Trials Open to Enrollment

Adult Trials:

A 6-week trial of an investigational medication given IV as an add-on treatment for Major Depressive Disorder.   Individuals 18 to 65 years with Major Depression who are on an antidepressant and have experienced less than a 50% improvement in their depressive symptoms may be eligible.  This program has two extension studies available.  For more information contact Colleen Figueroa, BS at 813-974-9104cfiguero@health.usf.edu.

An evaluation of the effectiveness of intranasal esKetamine compared to placebo, when given in addition to antidepressant medication, in reducing symptoms of Major Depression, including suicidal ideations.  Study includes 5 days of inpatient psychiatric hospitalization.  Individuals 18-64 years of age with a diagnosis of Major Depression may be eligible.  For more information, contact Kathy Smith, RN at 813-974-7006, ksmith5@health.usf.edu.

A clinical research trial of Brexpiprazole compared to placebo for the treatment of Bipolar Disorder.  Individuals 18-65 years of age, diagnosed with Bipolar disorder currently experiencing Manic or Mixed symptoms who are willing to be hospitalized for up to 14 days may be eligible to participate.  An outpatient, open-label extension study is available.  For more information, contact Kathy Smith, RN at 813-974-7006, ksmith5@health.usf.edu.  


Children & Adolescent Trials:

A 10-week study of an investigational medication for treatment of Major Depression in adolescents, 12-17 years of age.   For more information contact Colleen Figueroa, BS at 813-974-9104 , cfiguero@health.usf.edu.

A 12-week study of an investigational non-stimulant medication compared to placebo for the treatment of Attention Deficit/Hyperactivity Disorder (ADHD) in children ages 6-11 years, and in adolescents ages 12-17 years.  For more information contact Colleen Figueroa, BS at 813-974-9104, cfiguero@health.usf.edu.

A 10-week study of lisdexamfetamine dimesylate (Vvyanse) in children, ages 4-5 years, with Attention Deficit/Hyperactivity Disorder (ADHD).  An open-label extension study is also available.  For more information contact Colleen Figueroa, BS at 813-974-9104, cfiguero@health.usf.edu.


Seniors (Age 65+) Trials:

A 50-week study for individuals’ ages 60 to 90 years, with mild or moderate Alzheimer’s disease who complain of disrupted sleep or multiple awakenings at night.  For more information, contact Kathy Smith, RN at 813-974-7006, ksmith5@health.usf.edu.

 

Please contact us at 813-974-1404 to learn more about clinical research trials at USF Psychiatry. 
All study related visits, procedures, and study-medications are provided.