Dr. Emmanuel is Chairman and Professor of Pediatrics and Public Health. She is also on the faculty of the USF Department of Mental Health Law and Policy. She received her B.S. from the University of Notre Dame, and her M.D. from the University of Florida in Gainesville. She completed her pediatric residency at USF, where she also served as chief resident. After completing an infectious disease fellowship at USF in 1989 she joined the faculty. She served as Chief of Pediatric Infectious Disease from 1993 to 2012, when she was named the Lewis A. Barness Chair of Pediatrics. From 2007 to 2012, she was the Associate Dean for Clinical Research at the Morsani College of Medicine, and was founding Director of USF Health's Clinical and Translational Science Institute.
Dr. Emmanuel has been the Medical Director for Clinical Research at Tampa General Hospital since 2009 and since 1994, the Medical Director of the Pediatric/Adolescent HIV Program, She has participated in HIV policy making at the national level as a member of the Board of Directors of the HIV Medical Association and as a member of the Committee on Pediatric AIDS for the American Academy of Pediatrics. Her research focus is pediatric HIV/AIDs-specifically antiretroviral drug treatment for HIV, community-based methods of preventing perinatally-acquired HIV, and the long-term complications of HIV. Dr. Emmanuel has been the principal investigator for more than two dozen research studies related to HIV care and prevention.