Angel Luciano, MD

College Of Medicine Pediatrics

ECMO Medical Director, Pediatrics, University of South Florida/Tampa General Hospital

Contact Info 1 Tampa General Circle
Suite F170
Tampa, FL 33606

Academic Email:

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  • Post doctoral fellowship, Immunology, Case Western Reserve University, 2008
  • MD, Medicine, University Of Puerto Rico, 2001

Research Interests

  • Neonatal immunology and clinical outcomes


  • American Association for the Advancement of Science (AAAS) (Member, 2013 - Present)
  • Society for Pediatric Research (Member, 2011 - Present)
  • American Academy of Pediatrics (Fellow, 2004 - Present)

Recent Publications

  • Remon JI, Amin SC, Mehendale SR, Rao R, Luciano AA, Garzon SA, Maheshwari A. Depth of bacterial invasion in resected intestinal tissue predicts mortality in surgical necrotizing enterocolitis. Journal of perinatology : official journal of the California Perinatal Association. , 2015.
  • Thais Queliz Peña and Angel A. Luciano. Cord Blood T Lymphocytes Homeostasis and Prenatal Inflammation: A Proposed Model of Poor Clinical Outcomes Ann Pediatr Child Health. 1(2) : 1006, 2014.
  • Groer M, AA Luciano , Dishaw LJ, Ashmeade TL, Gilbert JA and Miller E. Development of the Preterm Infant Gut Microbiome: A Research Priority. Microbiome. 2(38) , 2014.
  • Angel A. Luciano, Ileana M. Arbona-Ramirez, Rene Ruiz, Braulio J. Llorens-Bonilla, Denise G. Martinez-Lopez, Nicholas Funderburg, Morna J. Dorsey. Alterations in Regulatory T Cell Subpopulations Seen in Preterm Infants PLoS ONE. 5(9) : e95867, 2014.
  • Martinez-Lopez DG, Funderburg NT, Cerissi A, Rifaie R, Aviles-Medina L, Llorens-Bonilla BJ, Sleasman J, Luciano AA. Lipopolysaccharide and soluble CD14 in cord blood plasma are associated with prematurity and chorioamnionitis. Pediatric research. , 2013.
  • Sugimoto J, Romani AM, Valentin-Torres AM, Luciano AA, Ramirez Kitchen CM, Funderburg N, Mesiano S, Bernstein HB. Magnesium decreases inflammatory cytokine production: a novel innate immunomodulatory mechanism Journal of Immunology. 12(188) : 6338-46, 2012.
  • Rodriguez B, Bazdar DA, Funderburg N, Asaad R, Luciano AA, Yadavalli G, Kalayjian RC, Lederman MM, Sieg SF. Frequencies of FoxP3+ naive T cells are related to both viral load and naive T cell proliferation responses in HIV disease. Journal Leuk Biol. 3(90) : 621-8, 2011.
  • Luciano AA, Yu H, Jackson LW, Wolfe LA, Bernstein HB. Preterm labor and chorioamnionitis are associated with neonatal T cell activation. PloS ONE. 2(6) : e16698, 2011.
  • Crespo M, Martinez DG, Cerissi A, Rivera-Reyes B, Bernstein HB, Lederman MM, Sieg SF, Luciano AA. Neonatal T-cell maturation and homing receptor responses to Toll-like receptor ligands differ from those of adult naive T cells: relationship to prematurity. Pediatric Research. 2(71) : 136-43, 2011.
  • Funderburg NT, Mayne E, Sieg SF, Asaad R, Jiang W, Kalinowska M, Luciano AA, Stevens W, Rodriguez B, Brenchley JM, Douek DC, Lederman MM. Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation. Blood. 2(115) : 161-7, 2010.
  • Funderburg N, Luciano AA, Jiang W, Rodriguez B, Sieg SF, Lederman MM. Toll-like receptor ligands induce human T cell activation and death, a model for HIV pathogenesis. PloS one. 4(3) : e1915, 2008.
  • Luciano AA, Lederman MM, Valentin-Torres A, Bazdar DA, Sieg SF. Impaired induction of CD27 and CD28 predicts naive CD4 T cell proliferation defects in HIV disease. Jounral of Immunology. 6(179) : 3543-9, 2007.
  • Ryan ET, Crean TI, Kochi SK, John M, Luciano AA, Killeen KP, Klose KE, Calderwood SB. Development of a DeltaglnA balanced lethal plasmid system for expression of heterologous antigens by attenuated vaccine vector strains of Vibrio cholerae. Infec Immun. 1(68) : 221-6, 2000.