Dennis K. Ledford

Dennis K. Ledford, MD

Professor, College of Medicine Pediatrics

Professor, College of Medicine Internal Medicine

Contact Info 13000 Bruce B Downs Blvd
VAR 111D
Tampa FL 33612

Academic Email: dledford@health.usf.edu

Academic Phone:(813) 972-7631

View My C.V.

Education

  • MD, University of Tennessee, 1976

Memberships

  • American Academy of Allergy Asthma and Immunology (Past-President, 2011 - Present)

Recent Publications

  • Ledford DK. Henoch-Schönlein Purpura and Influenza Vaccine. The journal of allergy and clinical immunology. In practice. 5(1) : 210, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28065339
  • Tabatabaian F, Ledford DK, Casale TB. Biologic and New Therapies in Asthma. Immunology and allergy clinics of North America. 37(2) : 329-343, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28366480
  • Saco TV Glaum MC Ledford DK Lockey RF, . Onset of psoriatic arthritis associated with multiple wasp stings. Ann Allergy Asthma Immunol.. 118(2) : 227-228. doi: 10.1016/j.anai.2016.10.022., 2017.
  • Ledford DK, Akin C. Tryptase Increase without Mastocytosis or Anaphylaxis. The journal of allergy and clinical immunology. In practice. 5(3) : 869, 2017. http://www.ncbi.nlm.nih.gov/pubmed/28483325
  • Ledford DK. Omalizumab and Allergic Reactions. The journal of allergy and clinical immunology. In practice. 4(1) : 187-8, 2017. http://www.ncbi.nlm.nih.gov/pubmed/26772933
  • Ledford DK, Wenzel S. Severe Asthma with Joint Pain, Thrombophilia, and Irritable Bowel Syndrome. The journal of allergy and clinical immunology. In practice. 4(5) : 1011-2, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27587324
  • Ledford DK. Hypogammaglobulinemia without Infection. The Journal of Allergy and Clinical Immunology. In practice. 4(4) : 790, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27393787
  • Ledford DK. Reply. The Journal of Allergy and Clinical Immunology. In practice. 4(1) : 189-90, 2016. http://www.ncbi.nlm.nih.gov/pubmed/26772934
  • Ledford DK. Skin Tests and In Vitro Tests for Insect Allergy. The Journal of Allergy and Clinical Immunology. In practice. 4(3) : 562-3, 2016. http://www.ncbi.nlm.nih.gov/pubmed/27157941
  • D'Amato G, Holgate ST, Pawankar R, Ledford DK, Cecchi L, Al-Ahmad M, Al-Enezi F, Al-Muhsen S, Ansotegui I, Baena-Cagnani CE, Baker DJ, Bayram H, Bergmann KC, Boulet LP, Buters JT, D'Amato M, Dorsano S, Douwes J, Finlay SE, Garrasi D, Gómez M, Haahtela T, Halwani R, Hassani Y, Mahboub B, Marks G, Michelozzi P, Montagni M, Nunes C, Oh JJ, Popov TA, Portnoy J, Ridolo E, Rosário N, Rottem M, Sánchez-Borges M, Sibanda E, Sienra-Monge JJ, Vitale C, Annesi-Maesano I. Meteorological conditions, climate change, new emerging factors, and asthma and related allergic disorders. A statement of the World Allergy Organization. The World Allergy Organization journal. 8(1) : 25, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26207160
  • Ledford DK. Optimal asthma diagnosis: A destination or a process? The Journal of allergy and clinical immunology. 136(3) : 654-5, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26100083
  • Tankersley MS, Ledford DK. Stinging insect allergy: state of the art 2015. The Journal of Allergy and Clinical Immunology. In practice. 3(3) : 315-22; quiz 323, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25956310
  • Lieberman P, Nicklas RA, Randolph C, Oppenheimer J, Bernstein D, Bernstein J, Ellis A, Golden DB, Greenberger P, Kemp S, Khan D, Ledford D, Lieberman J, Metcalfe D, Nowak-Wegrzyn A, Sicherer S, Wallace D, Blessing-Moore J, Lang D, Portnoy JM, Schuller D, Spector S, Tilles SA. Anaphylaxis-a practice parameter update 2015. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 115(5) : 341-84, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26505932
  • Bachert C, Larché M, Bonini S, Canonica GW, Kündig T, Larenas-Linnemann D, Ledford D, Neffen H, Pawankar R, Passalacqua G. Allergen immunotherapy on the way to product-based evaluation-a WAO statement. The World Allergy Organization journal. 8(1) : 29, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26417398
  • Ledford D, Orange J. Sinonasal Papillomas and Natural Killer-Cell Deficiency. The Journal of Allergy and Clinical Immunology. In practice. 3(4) : 647, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26164582
  • Choo E, Ledford D. Eosinophilic granulomatosis with polyangiitis (Churg-Strauss vasculitis). The Journal of Allergy and Clinical Immunology. In practice. 3(3) : 466-7; quiz 468, 2015. http://www.ncbi.nlm.nih.gov/pubmed/25956318
  • Choo E, Ledford D. Tracheobronchomalacia and Hyperdynamic Airway Collapse. The Journal of Allergy and Clinical Immunology. In practice. 3(4) : 644-5; quiz 646, 2015. http://www.ncbi.nlm.nih.gov/pubmed/26164581
  • Dennis K. Ledford, Sally E. Wenzel, Richard F. Lockey. Aspirin or Other Nonsteroidal Inflammatory Agent Exacerbated Asthma Journal of Allergy and Clinical Immunology: In Practice. 2(6) : 653-657, 2014.
  • Yáñez A, Cho SH, Soriano JB, Rosenwasser LJ, Rodrigo GJ, Rabe KF, Peters S, Niimi A, Ledford DK, Katial R, Fabbri LM, Celedón JC, Canonica GW, Busse P, Boulet LP, Baena-Cagnani CE, Hamid Q, Bachert C, Pawankar R, Holgate ST. Asthma in the elderly: what we know and what we have yet to know. The World Allergy Organization journal. 7(1) : 8, 2014. http://www.ncbi.nlm.nih.gov/pubmed/25152804
  • Mark C. Glaum, Eileen Rifkin, Jia-Wang Wang, Richard F. Lockey, Dennis K. Ledford. Real-Time PCR Quantification Of Virginia Live Oak (Quercus virginiana) Pollen (meeting abstract) Journal of Allergy and Clinical Immunology. 133(2) : AB18, 2014.
  • Lockey RF, Talreja N, Ledford DK. Asthma diagnosis and treatment - 1018. Effect of inhaled corticosteroids with long-acting beta2 agonists vs. inhaled corticosteroids alone on asthma control in children: results from national ashtma survey. The World Allergy Organization journal. 6 Suppl 1: P18, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23819646
  • Cowan, Gregory Michael, Neetu Talreja, Jennifer E. Fergeson, Mary Jelks, Dennis K. Ledford, and Richard F. Lockey. The Effect of Local Temperature, Wind Velocity and Rain On Aerobiology Sampling; Ten Year Study (2001-2011), Sarasota, Fl (meeting abstract) Journal of Allergy and Clinical Immunology. 131(2) : AB79, 2013.
  • Ledford DK, Lockey RF. Asthma and comorbidities. Current opinion in allergy and clinical immunology. 13(1) : 78-86, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23222157
  • Akdis CA, Bachert C, Cingi C, Dykewicz MS, Hellings PW, Naclerio RM, Schleimer RP, Ledford D. Endotypes and phenotypes of chronic rhinosinusitis: a PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. The Journal of allergy and clinical immunology. 131(6) : 1479-90, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23587334
  • Passalacqua G, Baena-Cagnani CE, Bousquet J, Canonica GW, Casale TB, Cox L, Durham SR, Larenas-Linnemann D, Ledford D, Pawankar R, Potter P, Rosario N, Wallace D, Lockey RF. Grading local side effects of sublingual immunotherapy for respiratory allergy: speaking the same language. The Journal of allergy and clinical immunology. 132(1) : 93-8, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23683513
  • Kaplan A, Ledford D, Ashby M, Canvin J, Zazzali JL, Conner E, Veith J, Kamath N, Staubach P, Jakob T, Stirling RG, Kuna P, Berger W, Maurer M, Rosén K. Omalizumab in patients with symptomatic chronic idiopathic/spontaneous urticaria despite standard combination therapy. The Journal of Allergy and Clinical Immunology. 132(1) : 101-9, 2013. http://www.ncbi.nlm.nih.gov/pubmed/23810097
  • Simons FE, Ardusso LR, Bilò MB, Dimov V, Ebisawa M, El-Gamal YM, Ledford DK, Lockey RF, Ring J, Sanchez-Borges M, Senna GE, Sheikh A, Thong BY, Worm M. 2012 Update: World Allergy Organization Guidelines for the assessment and management of anaphylaxis. Current opinion in allergy and clinical immunology. 12(4) : 389-399, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22744267
  • Lötvall J, Pawankar R, Wallace DV, Akdis CA, Rosenwasser LJ, Weber RW, Wesley Burks A, Casale TB, Lockey RF, Papadopoulos NG, Fineman SM, Ledford DK. We call for iCAALL: International Collaboration in Asthma, Allergy and Immunology. Allergy. 67(4) : 449-50, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22414196
  • Ledford DK, Burks AW, Ballow M, Cox L, Wood RA, Casale TB. Statement regarding "The public health benefits of air pollution control". The Journal of allergy and clinical immunology. 130(1) : 24, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22742836
  • Lötvall J, Pawankar R, Wallace DV, Akdis CA, Rosenwasser LJ, Weber RW, Burks AW, Casale TB, Lockey RF, Papadopoulos NG, Fineman SM, Ledford DK. We call for iCAALL: International Collaboration for Asthma, Allergy and Immunology. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 108(4) : 215-6, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22469437
  • Lötvall J, Pawankar R, Wallace DV, Akdis CA, Rosenwasser LJ, Weber RW, Burks AW, Casale TB, Lockey RF, Papadopoulos NG, Fineman SM, Ledford DK. We call for iCAALL: International Collaboration in Asthma, Allergy and Immunology. The Journal of allergy and clinical immunology. 129(4) : 904-5, 2012. http://www.ncbi.nlm.nih.gov/pubmed/22365583
  • Phillips JF, Lockey RF, Fox RW, Ledford DK, Glaum MC. Systemic reactions to subcutaneous allergen immunotherapy and the response to epinephrine. Allergy and asthma proceedings : the official journal of regional and state allergy societies. 32(4) : 288-94, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21781404
  • Parkerson J, Ledford D. Mannitol as an indirect bronchoprovocation test for the 21st century. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 106(2) : 91-6, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21277509
  • Simons FE, Ardusso LR, Bilò MB, El-Gamal YM, Ledford DK, Ring J, Sanchez-Borges M, Senna GE, Sheikh A, Thong BY. World Allergy Organization anaphylaxis guidelines: summary. The Journal of allergy and clinical immunology. 127(3) : 587-93.e1-22, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21377030
  • Hanania NA, King MJ, Braman SS, Saltoun C, Wise RA, Enright P, Falsey AR, Mathur SK, Ramsdell JW, Rogers L, Stempel DA, Lima JJ, Fish JE, Wilson SR, Boyd C, Patel KV, Irvin CG, Yawn BP, Halm EA, Wasserman SI, Sands MF, Ershler WB, Ledford DK. Asthma in the elderly: Current understanding and future research needs--a report of a National Institute on Aging (NIA) workshop. The Journal of allergy and clinical immunology. 128(3 Suppl) : S4-24, 2011. http://www.ncbi.nlm.nih.gov/pubmed/21872730
  • Lieberman P, Nicklas RA, Oppenheimer J, Kemp SF, Lang DM, Bernstein DI, Bernstein JA, Burks AW, Feldweg AM, Fink JN, Greenberger PA, Golden DB, James JM, Kemp SF, Ledford DK, Lieberman P, Sheffer AL, Bernstein DI, Blessing-Moore J, Cox L, Khan DA, Lang D, Nicklas RA, Oppenheimer J, Portnoy JM, Randolph C, Schuller DE, Spector SL, Tilles S, Wallace D. The diagnosis and management of anaphylaxis practice parameter: 2010 update. The Journal of allergy and clinical immunology. 126(3) : 477-80.e1-42, 2010. http://www.ncbi.nlm.nih.gov/pubmed/20692689
  • Ledford DK. Omalizumab: overview of pharmacology and efficacy in asthma. Expert opinion on biological therapy. 9(7) : 933-43, 2009. http://www.ncbi.nlm.nih.gov/pubmed/19527111
  • Canonica GW, Bousquet J, Casale T, Lockey RF, Baena-Cagnani CE, Pawankar R, Potter PC, Bousquet PJ, Cox LS, Durham SR, Nelson HS, Passalacqua G, Ryan DP, Brozek JL, Compalati E, Dahl R, Delgado L, van Wijk RG, Gower RG, Ledford DK, Filho NR, Valovirta EJ, Yusuf OM, Zuberbier T, Akhanda W, Almarales RC, Ansotegui I, Bonifazi F, Ceuppens J, Chivato T, Dimova D, Dumitrascu D, Fontana L, Katelaris CH, Kaulsay R, Kuna P, Larenas-Linnemann D, Manoussakis M, Nekam K, Nunes C, O'Hehir R, Olaguibel JM, Onder NB, Park JW, Priftanji A, Puy R, Sarmiento L, Scadding G, Schmid-Grendelmeier P, Seberova E, Sepiashvili R, Solé D, Togias A, Tomino C, Toskala E, Van Beever H, Vieths S. Sub-lingual immunotherapy: World Allergy Organization Position Paper 2009. Allergy. 64 Suppl 91: 1-59, 2009. http://www.ncbi.nlm.nih.gov/pubmed/20041860
  • Lockey RF, Ledford DK. Allergens and allergen immunotherapy. Preface. Clinical allergy and immunology. 21: vii, 2008. http://www.ncbi.nlm.nih.gov/pubmed/18828494
  • Cole SL, Ledford DK, Lockey RF, Daas A, Kooper J. Primary gastrointestinal lymphangiectasia presenting as cryptococcal meningitis. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 98(5) : 490-2, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17521035
  • Chacko T, Ledford D. Peri-anesthetic anaphylaxis. Immunology and allergy clinics of North America. 27(2) : 213-30, vi, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17493499
  • Miller AC, Chacko T, Rashid RM, Ledford DK. Fever of unknown origin and isolated noncaseating granuloma of the marrow: could this be sarcoidosis? Allergy and asthma proceedings : the official journal of regional and state allergy societies. 28(2) : 230-5, 2007. http://www.ncbi.nlm.nih.gov/pubmed/17479610
  • Singam R, Jena PK, Behera S, Hellermann GR, Lockey RF, Ledford D, Mohapatra SS. Combined fluticasone propionate and salmeterol reduces RSV infection more effectively than either of them alone in allergen-sensitized mice. Virology journal. 3: 32, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16719922
  • Bielory L, Blaiss M, Fineman SM, Ledford DK, Lieberman P, Simons FE, Skoner DP, Storms WW. Concerns about intranasal corticosteroids for over-the-counter use: position statement of the Joint Task Force for the American Academy of Allergy, Asthma and Immunology and the American College of Allergy, Asthma and Immunology. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 96(4) : 514-25, 2006. http://www.ncbi.nlm.nih.gov/pubmed/16680921
  • Ramey JT, Ledford D. Daily corticosteroids were not better than as-needed corticosteroids in mild persistent asthma. ACP journal club. 143(3) : 60, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16262217
  • Bukstein DA, Jones CA, Ledford DK, Smith P, Wechsler ME, Urbano FL. Discussing the COSTS of asthma: controlling outcomes, symptoms, and treatment strategies. The American journal of managed care. 11(11 Suppl) : S318-S336; quiz S337-S339, 2005. http://www.ncbi.nlm.nih.gov/pubmed/16236015
  • Ledford DK. Is oral immunotherapy too good to be true? Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 92(1) : 1-2, 2004. http://www.ncbi.nlm.nih.gov/pubmed/14756456
  • Ledford D. Inadequate diagnosis of nonallergic rhinitis: assessing the damage. Allergy and asthma proceedings : the official journal of regional and state allergy societies. 24(3) : 155-62, 2003. http://www.ncbi.nlm.nih.gov/pubmed/12866317
  • Ramirez NC, Ledford DK. Immunotherapy for allergic asthma. The Medical clinics of North America. 86(5) : 1091-112, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12432871
  • Lilly CM, Churg A, Lazarovich M, Pauwels R, Hendeles L, Rosenwasser LJ, Ledford D, Wechsler ME. Asthma therapies and Churg-Strauss syndrome. The Journal of allergy and clinical immunology. 109(1) : S1-19, 2002. http://www.ncbi.nlm.nih.gov/pubmed/11799357
  • Ledford DK. Inflammation and asthma: here, there, everywhere. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 89(4) : 346-7, 2002. http://www.ncbi.nlm.nih.gov/pubmed/12392376

Awards/Honors

  • Best Allergist/Immunologist in Tampa Bay (Tampa Bay Magazine - 2015)
  • Professionalism Award (Graduating Medical Class 2015, MCOM - 2015)
  • Listed in the “America’s Top Doctors” Guide (America's Top Doctors - 2010)