Type-1 Diabetes

The TrialNet clinical research group was created to study the natural history of, perform multi-center randomized, controlled, clinical trials of prevention and early intervention of and investigate the genomics of Type 1 Diabetes. The primary objective of TrialNet is to conduct studies designed to evaluate novel approaches to the prevention and amelioration of T1D by disrupting the disease process. The TrialNet studies provide an opportunity to fill important gaps in our understanding of the etiology of the events leading to T1D by studying a variety of aspects of the disease process, from studying high-risk individuals and relatives to a systematic screening of candidate environmental and genetic factors. The TrialNet studies will apply "cutting edge" molecular immunologic and genetic techniques to samples collected in high-risk individuals. In addition, samples collected by TrialNet will create a valuable resource for investigators proposing innovative hypotheses concerning candidate environmental and genetic factors.

Sites Include:

  • Benaroya Research Institute at Virginia Mason, Seattle WA
  • Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, CO
  • University of California, San Francisco, San Fransisco, CA
  • Stanford University Medical Center, Stanford, CA
  • University of Texas, Southwestern Medical Center at Dallas, Dallas, TX
  • University of Minnesota, Minneapolis, MN
  • Riley Hospital for Children, Indiana University, Indianapolis, IN
  • Naomi Berrie Diabetes Center, Columbia University, New York, NY
  • Yale University School of Medicine, New Haven, CT
  • Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA
  • University of Florida, Gainesville, FL
  • University of Miami, School of Medicine, Miami, FL
  • The Hospital for Sick Children, Toronto, Ontario, CA
  • University of Turku, Department of Pediatrics, Turku, Finland
  • University of Bristol, Bristol, UK
  • Vita-Salute San Raffaele University, Milan, Italy
  • Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria


To view all TrialNet studies, please visit: